Jennifer Sorrell, MD is originally from Rochester, New York. Dr. Sorrell is a pediatric dermatology specialist and joined our faculty in July of 2015. She received her BS from the University of Maryland at College Park in 2001 and earned her medical degree from Temple University School of Medicine in 2005. She completed her Pediatrics training and then Dermatology training at Northwestern University in 2008 and 2014 respectively. She completed a Pediatric Dermatology Fellowship at Columbia University in 2015. Dr. Sorrell is greatly interested in the complex mechanisms underlying inflammatory skin diseases, including atopic dermatitis and psoriasis. She is currently a member of the Society for Pediatric Dermatology, Women’s Dermatologic Society, American Academy of Pediatrics, and the American Academy of Dermatology.

Clinical Focus

  • Dermatology

Academic Appointments

Professional Education

  • Fellowship:Columbia University Medical Center (2015) NYUnited States of America
  • Board Certification: Pediatric Dermatology, American Board of Dermatology (2016)
  • Medical Education:Temple University School of Medicine Registrar (2005) PA
  • Board Certification: Dermatology, American Board of Dermatology (2014)
  • Residency:McGaw Medical Center of Northwestern University (2014) IL
  • Board Certification: Pediatrics, American Board of Pediatrics (2008)
  • Residency:McGaw Medical Center of Northwestern University (2008) IL


All Publications

  • Shedding Light on Alopecia Areata in Pediatrics: A Retrospective Analysis of Comorbidities in Children in the National Alopecia Areata Registry PEDIATRIC DERMATOLOGY Sorrell, J., Petukhova, L., Reingold, R., Christiano, A., Garzon, M. 2017; 34 (5): E271–E272


    Alopecia areata (AA) is a common autoimmune disease and it is challenging to predict which patients will have severe disease. The purpose of this retrospective study was to identify comorbidities in children enrolled in the National Alopecia Areata Registry. Atopic dermatitis was more common in patients with severe AA than in those with mild disease. The most common autoimmune comorbidities were vitiligo, psoriasis, thyroid disease, and juvenile idiopathic arthritis.

    View details for PubMedID 28884897

  • Score of Toxic Epidermal Necrosis Predicts the Outcomes of Pediatric Epidermal Necrolysis PEDIATRIC DERMATOLOGY Sorrell, J., Anthony, L., Rademaker, A., Belknap, S. M., Callahan, S., West, D. P., Paller, A. S. 2017; 34 (4): 433–37


    Epidermal necrolysis (Stevens-Johnson syndrome and toxic epidermal necrolysis) includes immune-mediated, life-threatening inflammatory blistering disorders that can affect children. The Score of Toxic Epidermal Necrosis (SCORTEN) tool has accurately predicted the outcome of these disorders in adults but has not been tested in children.We performed a retrospective chart review to compare the accuracy of the adult SCORTEN tool with that of two modifications tailored to children in predicting disease outcome.The longer the patient's median length of hospital stay was, the higher the adult and two proposed pediatric SCORTENs were. In addition, all patients who died had SCORTENs greater than 4.The pediatric-modified tools were not superior to the adult SCORTEN, which accurately predicted outcome.

    View details for DOI 10.1111/pde.13172

    View details for Web of Science ID 000405121100032

    View details for PubMedID 28508417

  • Use of Transparent Film Dressing for Dermoscopy of Mucosal Lesions PEDIATRIC DERMATOLOGY Sorrell, J., Lauren, C. T. 2016; 33 (1): 106-107


    Genital and mucosal nevi are not uncommonly encountered in children. These type of nevi highlight challenges in performing a thorough dermoscopic examination. Contact dermoscopy can provide additional information about a nevus that non-contact dermoscopy cannot. We propose applying a sterile transparent film dressing over the dermatoscope to act as a waterproof barrier that is also impermeable to bacteria and viruses. This provides a sanitary way to evaluate nevi in genital skin as well as on other mucosal surfaces.

    View details for DOI 10.1111/pde.12661

    View details for Web of Science ID 000373066300035

  • Eruptive Xanthomas Masquerading as Molluscum Contagiosum PEDIATRICS Sorrell, J., Salvaggio, H., Garg, A., Guo, L., Duck, S. C., Paller, A. S. 2014; 134 (1): E257-E260


    Eruptive xanthomas are cutaneous manifestations of hyperlipidemias in which lipids accumulate in large foam cells within the skin. They classically present as crops of 1- to 4-mm yellow-orange papules and are often associated with extreme hypertriglyceridemia. We describe a 12-year-old boy with autism who was thought to have widespread molluscum contagiosum for a year before dermatologic consultation was obtained. Recognition of eruptive xanthomas led to the discovery of massive hypertriglyceridemia (serum triglycerides 6853 mg/dL) and diabetes mellitus. Through medical intervention, including insulin and fenofibrate therapy, and dietary modification with weight loss, the xanthomas cleared during the subsequent months, and his serum triglyceride levels nearly normalized.

    View details for DOI 10.1542/peds.2013-2108

    View details for Web of Science ID 000338774800031

    View details for PubMedID 24918225

  • Life-threatening dermatologic adverse events in oncology ANTI-CANCER DRUGS Rosen, A. C., Balagula, Y., Raisch, D. W., Garg, V., Nardone, B., Larsen, N., Sorrell, J., West, D. P., Anadkat, M. J., Lacouture, M. E. 2014; 25 (2): 225-234


    The incidences of life-threatening toxicities such as Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are inconsistently reported. The potential association of anticancer agents with SJS or TEN has not been systematically investigated. We searched the literature (Ovid: 1950 to June 2013 and PubMed: 1948 to June 2013) using terms for SJS/TEN and anticancer therapies. Primary case reports, case series, and clinical trials were included. In addition, MedWatch, the Food and Drug Administration Adverse Event Reporting System (FAERS), was searched (1968 to August 2012) for SJS/TEN reports associated with anticancer therapies. Proportional reporting ratios (PRR>2, N>3), empirical Bayes geometric mean (EBGM>2, N>3), and lower 95% confidence interval (EBGM0.05>2) were used as thresholds to constitute a signal of association between SJS/TEN and anticancer drugs. There were 46 SJS and 37 TEN cases associated with 18 and 22 anticancer drugs in the literature, respectively. Among cases in the FAERS, significant signals were associated with SJS for bendamustine and with TEN for bendamustine, busulfan, chlorambucil, fludarabine, lomustine, and procarbazine. Several drugs reported in the published literature to be associated with SJS/TEN were not found to have significant signals in FAERS. Proactive pharmacovigilance to detect and define safety signals serves to aid oncology practitioners in the recognition of possible, yet uncommon, serious, and/or life-threatening skin reactions.

    View details for DOI 10.1097/CAD.0000000000000032

    View details for Web of Science ID 000329876400012

    View details for PubMedID 24108082

  • Topical Timolol 0.5% Gel-Forming Solution for Small Deep Facial Infantile Hemangiomas PEDIATRIC DERMATOLOGY Sorrell, J., Chamlin, S. L. 2013; 30 (5): 592-594


    We report three cases of successful treatment of proliferating deep infantile hemangiomas with topical timolol 0.5% gel-forming solution (GFS) used two to three times daily. We recommend considering timolol as an initial option for small, deep facial hemangiomas that are not causing functional compromise or complications but may have an unsatisfactory cosmetic appearance. In our experience, albeit limited, this is a safe alternative to watchful waiting.

    View details for DOI 10.1111/pde.12209

    View details for Web of Science ID 000324092500030

    View details for PubMedID 23889228

  • Dermatoscopic evolution of dysplastic nevi showing high-grade dysplasia in a metastatic melanoma patient on vemurafenib JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY Gerami, P., Sorrell, J., Martini, M. 2012; 67 (6): E275-E276

    View details for DOI 10.1016/j.jaad.2012.05.031

    View details for Web of Science ID 000312131200016

    View details for PubMedID 23158636

  • Update in Molecular Diagnostics in Melanocytic Neoplasms ADVANCES IN ANATOMIC PATHOLOGY Cooper, C., Sorrell, J., Gerami, P. 2012; 19 (6): 410-416


    Future classification systems for melanocytic neoplasms will likely include the integration of molecular aberrations. A number of studies have shown that many gene mutations and chromosomal copy number aberrations may correlate with characteristic clinical and morphologic features for melanocytic neoplasms. This review discusses newly described familial germline mutations such as the BRCA1-associated protein-1 familial melanoma syndrome, recently described somatic mutations, and chromosomal copy number aberrations recently described in melanoma. Further, we discuss how these specific molecular aberrations correlate with specific clinical and morphologic features in melanocytic neoplasm and their implications for prognosis and molecular diagnostics. In addition, we discuss state of the art advancements in molecular diagnostics for melanocytic neoplasms and newly developed fluorescence in situ hybridization assays including the utility of fluorescence in situ hybridization for 9p21 in spitzoid melanocytic neoplasms. Lastly, we discuss a phenomenon known as paradoxical activation of wild-type BRAF seen in patients treated with vemurafenib and some potential clinical presentations of this process.

    View details for DOI 10.1097/PAP.0b013e318271a5cb

    View details for Web of Science ID 000309968400006

    View details for PubMedID 23060066

  • Pathogenesis-Based Therapy Reverses Cutaneous Abnormalities in an Inherited Disorder of Distal Cholesterol Metabolism JOURNAL OF INVESTIGATIVE DERMATOLOGY Paller, A. S., van Steensel, M. A., Rodriguez-Martin, M., Sorrell, J., Heath, C., Crumrine, D., van Geel, M., Noda Cabrera, A., Elias, P. M. 2011; 131 (11): 2242-2248


    Identification of the underlying genetic, cellular, and biochemical basis of lipid metabolic disorders provides an opportunity to deploy corrective, mechanism-targeted, topical therapy. We assessed this therapeutic approach in two patients with Congenital Hemidysplasia with Ichthyosiform erythroderma and Limb Defects (CHILD) syndrome, an X-linked dominant disorder of distal cholesterol metabolism. On the basis of the putative pathogenic role of both pathway-product deficiency of cholesterol and accumulation of toxic metabolic intermediates, we assessed the efficacy of combined therapy with lovastatin and cholesterol. We also evaluated the basis for the poorly understood, unique lateralization of the cutaneous and bone malformations of CHILD syndrome by analyzing gene activation in abnormal and unaffected skin. Ultrastructural analysis of affected skin showed evidence of both cholesterol depletion and toxic metabolic accumulation. Topical treatment with lovastatin/cholesterol (but not cholesterol alone) virtually cleared skin lesions by 3 months, accompanied by histological and ultrastructural normalization of epidermal structure and lipid secretion. The unusual lateralization of abnormalities in CHILD syndrome reflects selective clearance of keratinocytes and fibroblasts that express the mutant allele from the unaffected side. These findings validate pathogenesis-based therapy that provides the deficient end product and prevents accumulation of toxic metabolites, an approach of potential utility for other syndromic lipid metabolic disorders.

    View details for DOI 10.1038/jid.2011.189

    View details for Web of Science ID 000296240100018

    View details for PubMedID 21753784

  • Oral Sucrose for Pain Relief in Young Infants with Hemangiomas Treated with Intralesional Steroids PEDIATRIC DERMATOLOGY Sorrell, J., Carmichael, C., Chamlin, S. 2010; 27 (2): 154-155


    Intralesional corticosteroids are one preferred method for treating small localized infantile hemangiomas because of efficacy in halting proliferation and minimal systemic side effects. Although often efficacious, this procedure is uncomfortable for infants. We describe the successful use of an oral 24% sucrose solution given via needleless syringe to the anterior tip of the tongue or in combination with a pacifier as an analgesic during intralesional injection of infantile hemangioma. Options for anesthesia in this young age group include topical prilocaine/lidocaine, injectable lidocaine, and parent soothing. Most often, topical or intralesional anesthesia is deferred when treating hemangiomas of infancy with intralesional corticosteroids. We use oral sucrose as a compassionate option.

    View details for DOI 10.1111/j.1525-1470.2010.01120.x

    View details for Web of Science ID 000276949400007

    View details for PubMedID 20537065

  • A 7-day-old Boy with a Congenital Vascular Nodule PEDIATRIC ANNALS Sorrell, J., Chamlin, S. L. 2010; 39 (2): 63-65

    View details for DOI 10.3928/00904481-20100120-04

    View details for Web of Science ID 000274638200004

    View details for PubMedID 20166633