School of Medicine


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  • Yuan-Hung Lo

    Yuan-Hung Lo

    Postdoctoral Research Fellow, Hematology

    Bio I am currently working on several projects to understand the control of gastrointestinal and cancer stem cell biology, especially how critical intrinsic genetic mutations and extrinsic extracellular components within the microenvironment influence cell behaviors. Stem cells of the gastrointestinal tract give rise to the surface lining of the epithelium, and must continuously produce new cells to replace those shed into the lumen throughout the lifespan. When mutations accumulate in these stem cells, they can grow uncontrollably into benign polyps or malignant tumors. In Dr. Calvin Kuo’s laboratory, I have used transgenic mice and primary human organoids as the models. Human organoids provide a robust primary culture system to recapitulate 3D structure and multilineage differentiation, which represents an underutilized method for the study of stem cell and cancer biology. I have focused my efforts on establishing next generation CRISPR/Cas9 genome editing tools in these orgnaoids, and applying this powerful system to gain insight into how different signaling pathways can contribute to gastrointestinal stem cell activity and tumorigenesis .

  • Michitaka Nakano

    Michitaka Nakano

    Postdoctoral Research Fellow, Hematology

    Current Research and Scholarly Interests Understanding of tumor biology using cancer organoid from the clinical view point.

  • Ilana Rachel Yurkiewicz

    Ilana Rachel Yurkiewicz

    Postdoctoral Medical Fellow, Hematology

    Bio I am a fellow physician specializing in hematology and oncology. I spend my time directly caring for patients, advocating for them as a medical journalist, and researching ways to improve their lives.

    My research focus is in hematological malignancies. I explore questions relating to clinical outcomes, quality of life, end-of-life communication, and novel therapeutics in acute leukemias.

    As a writer, I strive to bridge the gaps between academic medicine and everyday lives. I am a former AAAS Mass Media Fellow, and as a medical student I created and wrote a blog column at Scientific American on the thoughts of a trainee. I now write the Hard Questions column at Hematology News. My writing has also appeared in Undark Magazine, Health Affairs, STAT News, Aeon Magazine, Science Progress, and The News & Observer and has been republished in The Atlantic and The Best American Science and Nature Writing 2019 anthology.

    I have an academic interest in bioethics. I interned with the Presidential Commission for the Study of Bioethical Issues, and I have done ethics research on return of incidental findings and physicians’ interpretations of code statuses. My ethics papers have been published in the New England Journal of Medicine, Penn Bioethics Journal, and Ivy Journal of Ethics.

    I’ve also done research in genomics and bioinformatics and the use of telemedicine to augment subspecialty care.

    Above all else, I am passionate about providing thoughtful, compassionate, and holistic care for my patients.

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