Safety and Tolerability Study of SNS-314 for Advanced Solid Tumors

This is a study to assess the safety and tolerability of SNS-314 in advanced solid tumors in humans.

Stanford is currently not accepting patients for this trial.

Stanford Investigator(s):

Intervention(s):

  • drug: SNS-314

Eligibility


Inclusion Criteria:

   - Advanced solid tumor and that is measurable by a scan

Exclusion Criteria:

   - Uncontrolled or untreated central nervous system metastases

   - Cerebrovascular accident/transient ischemic attack up to 6 months before Cycle 1 Day 1

   - Any of the following cardiac conditions:

   - History of myocardial infarction, acute coronary syndromes up to 12 weeks before Cycle
   1 Day 1

   - Class III or IV heart failure up to 6 months before Cycle 1 Day 1

   - Baseline heart rate corrected QT interval (QTc)> 450 msec

   - History of ventricular arrhythmias up to 6 months before Cycle 1 Day 1

   - Use of medications that prolong the QTc interval and are associated with Torsades de
   Pointe (TdP)

   - Previous cancer treatment up to 21 days before first dose

   - Any investigational therapy up to 28 days before Cycle 1 Day 1

   - Known allergy to cyclodextrins

Please note: There are additional inclusion/exclusion criteria for this study. Please
contact the study center for additional information and to determine if all study criteria
are met.

Ages Eligible for Study

18 Years - N/A

Genders Eligible for Study

All

Our research team includes physicians, residents, medical students, research assistants, and volunteers. Our research topics include medical imaging, device validation,  mobile application development, and pharmaceutical trials.  

Some of the Neuro-Opthalmic concerns we investigate include Multiple Sclerosis, Optic Neuritis, IIH, and ICP.