Stanford-HBMC Research Retreat

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Abstract B13

Alex Ladd, BS, MS

Presenter

Name Alex Ladd, BS, MS
Classification/School Student, Morehouse School of Medicine

Alex Ladd, BS, MS
Student, Morehouse School of Medicine

Abstract

Title Implementation of 3D printed vasculature in CABG procedure
Authors Alex Ladd, Joseph Woo
Abstract

Coronary artery disease is a common heart problem, in which blood vessels have difficulty delivering blood to the heart due to cholesterol buildup. A coronary artery bypass graft (CABG) surgery restores blood flow to an obstructed area and can help improve survival in patients with advanced coronary artery disease. Complications such as infections at the incision site can cause health risks that can endanger the patient. In the last few years, 3D bioprinting vasculature and organ tissues have been investigated because it offers the potential to create patient-specific tissue & personalized treatment plans. 3D bioprinting of vasculature could offer the chance to produce functional tissue to be used in a CABG surgery. This would eliminate the need for a second incision site. This experiment aims to create a bioink blend that will be biocompatible and biodegradable so that the printed scaffold can degrade and the perfused extracellular matrix (ECM) and smooth muscle cells(SMC) of the patient will remain an intact vessel. The results should yield a 1cm vessel of the patient's cells grown from the printed scaffold. 

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