The Stanford Global Cardiac Surgery Research laboratory focuses on closing the disparity gap in access to cardiac surgical care worldwide through research and sustainable interventions. We engage with partners in local communities, and prioritize the work that our colleagues and patients have identified. Our current research involves evaluating the cost-effectiveness of cardiac surgery in a global context in order to advocate for capacity-building in low-resource settings, as well as investigating the outcomes in women who get pregnant after valve replacement surgery. We also are training the next generation of surgeons and cardiac surgeons with the GlobalSurgBox, which is a portable and affordable surgical training kit that we have distributed to our partners in Kenya, Rwanda, and training programs throughout the United States. We translate our research into evidence-based practice and policy changes to provide the best care for this vulnerable patient population.