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An Open-Label, Dose-Escalation, Phase 1/2 Study of the Oral Formulation of IXAZOMIB (MLN9708), Administered Twice-weekly in Combination With Lenalidomide and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Requiring Systemic Treatment

This will be a phase 1/2, multicenter, open-label study using the oral formulation of IXAZOMIB administered twice weekly in combination with lenalidomide and low-dose dexamethasone. Both phases of the study will include patients who have newly diagnosed multiple myeloma and have not previously received systemic treatment. Both the phase 1 and the phase 2 portions of the study will include induction therapy consisting of 1 year of therapy followed by maintenance therapy that will continue until progressive disease or unacceptable toxicity. Maintenance therapy will be IXAZOMIB alone on Days 1,4,8, & 11 of a 21-day cycle.

Stanford is not currently accepting new patients for this trial. You may want to check to see if other locations are recruiting.



  • drug : IXAZOMIB + Lenalidomide + Dexamethasone

Phase: Phase 1/Phase 2


Ages Eligible For Study:

18 Years - N/A

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Contact information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Cancer Clinical Trials Office
Not Recruiting

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