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An Open-label, Multicenter Extension Study of GDC-0449 (Hedgehog Pathway Inhibitor) in Patients Treated With GDC-0449 in a Previous Genentech-sponsored Phase I or Phase II Cancer Study

This was a multicenter, open-label extension study. Patients who received vismodegib (GDC-0449) in a Genentech-sponsored study and who had completed the parent study or who continued to receive vismodegib at the time the parent study closed were eligible for continued treatment in this protocol.

Stanford is not currently accepting new patients for this trial. You may want to check to see if other locations are recruiting.



  • drug : bevacizumab
  • drug : Vismodegib
  • drug : FOLFOX
  • drug : FOLFIRI

Phase: Phase 2


Ages Eligible For Study:

18 Years - N/A

Inclusion Criteria

- Completed vismodegib treatment within 2-4 weeks in a Genentech-sponsored parent study or continued to receive vismodegib at the time the Genentech-sponsored parent study closed. - Expectation by the investigator that the participant may continue to benefit from additional vismodegib treatment.

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Contact information

Primary Contact:

Shruthi Rangaraj 6507217159

Stanford University School of Medicine 300 Pasteur Drive Stanford, CA 94305

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