Randomized Phase III Trial of Consolidation Therapy With Bortezomib (VelcadeŽ)-Lenalidomide (RevlimidŽ) -Dexamethasone (VRD) Versus Bortezomib (VelcadeŽ)-Dexamethasone (VD) for Patients With Multiple Myeloma Who Have Completed a Dexamethasone Based Induction Regimen
This randomized phase III trial is studying bortezomib, dexamethasone, and lenalidomide to see how well they work compared with bortezomib and dexamethasone in treating patients with multiple myeloma previously treated with dexamethasone. Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as dexamethasone, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Lenalidomide may stimulate the immune system in different ways and stop cancer cells from growing. It is not yet known whether giving bortezomib together with dexamethasone is more effective with or without lenalidomide in treating multiple myeloma.
Stanford is not currently accepting new patients for this trial. You may want to check clinicaltrials.gov to see if other locations are recruiting.
- drug : Bortezomib
- drug : Lenalidomide
- drug : Dexamethasone
- procedure : quality-of-life assessment
Phase: Phase 3
Ages Eligible For Study: