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A Phase II Study of Cyclosporine in the Treatment of Angioimmunoblastic T-Cell Lymphoma

RATIONALE: Cyclosporine may help the immune system slow the growth of angioimmunoblastic T-cell lymphoma. PURPOSE: This phase II trial is studying how well cyclosporine works in treating patients with recurrent or refractory angioimmunoblastic T-cell lymphoma.

Stanford is not currently accepting new patients for this trial. You may want to check to see if other locations are recruiting.



  • drug : cyclosporine

Phase: Phase 2


Ages Eligible For Study:

18 Years - N/A

Inclusion Criteria

- Diagnosis of angioimmunoblastic T-cell lymphoma (recurrent or refractory) based on histologic examination. - At least one objective measurable or evaluable disease parameter. - Have failed at least one type of treatment: chemotherapy, auto-transplant, or steroid treatment. Patients may not receive concurrent chemotherapy. - Eastern Cooperative Oncology Group (ECOG) performance status of 0-2. - Adequate renal function as indicated by creatinine <= 1.5 the upper limit of normal (ULN). - Adequate liver function as indicated by alkaline phosphatase, Aspartate Aminotransferase (AST), and Alanine Aminotransferase (ALT) <= 2x the upper limit of normal. - Total bilirubin <= 2x the upper limit of normal. - Age 18 or older.

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Contact information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Cancer Clinical Trials Office
Not Recruiting

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