An Investigational Drug, Crizotinib (PF-02341066), Is Being Studied In Tumors, Except Non-Small Cell Lung Cancer, That Are Positive For Anaplastic Lymphoma Kinase (ALK)

This is a Phase 1 trial evaluating the safety and efficacy of crizotinib in patients with tumors except non-small cell lung cancer that are positive for ALK.

Stanford is currently not accepting patients for this trial.

Intervention(s):

  • drug: Crizotinib

Eligibility


Inclusion Criteria:

   - histologically or cytologically proven diagnosis of malignancy other than NSCLC

   - positive for translocation or inversion event involving the ALK gene locus

   - positive for ALK amplification events

   - positive for ALK activating point mutations

Exclusion Criteria:

   - mutations of amplifications involving the c-Met gene but not the ALK gene

   - concurrent treatment on another therapeutic clinical trial

   - prior therapy specifically directed against ALK

Ages Eligible for Study

15 Years - N/A

Genders Eligible for Study

All

Not currently accepting new patients for this trial

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Alyson Falwell
650-736-4281
Not Recruiting

Our research team includes physicians, residents, medical students, research assistants, and volunteers. Our research topics include medical imaging, device validation,  mobile application development, and pharmaceutical trials.  

Some of the Neuro-Opthalmic concerns we investigate include Multiple Sclerosis, Optic Neuritis, IIH, and ICP.