Sanjiv Sam Gambhir, MD, PhD

Clinical Focus

• Nuclear Medicine
• Radiology
• PET Scan

Administrative Appointments

• Director, Canary Center for Cancer Early Detection at Stanford (2009 - present)
• Professor, Bioengineering (2005 - present)
• Director, Molecular Imaging Program at Stanford (MIPS) (2003 - present)
• Head, Division of Nuclear Medicine (2003 - present)
• Professor, Department of Radiology and Bio-X Program (2003 - present)

Honors and Awards

• Parmley Prize, American College of Cardiology Foundations (2009)
• Stanford University Endowed Professorship, Virginia and D. K. Ludwig Professor for Clinical Investigation in Cancer Research (2009)
• IOM member, Institute of Medicine of the National Academies. (2008)
• Tesla Medal, UK Royal College of Radiologists (2008)
• ASCI member, American Society of Clinical Investigation - honor society for physicans/scientists. (2008)

Professional Education

Postdoctoral Advisees

Benjamin Cosgrove, Anca Dragulescu-Andrasi, Hua Fan-Minogue, Eric Gonzalez, Ben Hackel, Henry Haeberle, Aileen Hoehne, Sharon Hori, Mei Huang, Nicholas Hughes, Ken Ito, Michelle James, Jesse Jokerst, Sri Rajasekhar Kothapalli, Pingchuan Li, Natesh Parashurama, Jennifer Prescher, John Ronald, Arghavan Salles, Bin Shen, Abhinav Singh, Bryan Smith, Cristina Zavaleta, Keren Ziv

Web Site Links

• Molecular Imaging Program at Stanford

Industry Relationships

Stanford is committed to ethical and transparent interactions with our industry partners. It is our policy to disclose payments of $5,000 or more, equity valued at $5,000 or more in a publicly traded company, or any equity in a privately held company, to physicians and scientists employed by Stanford University from companies or other commercial entities with which they interact as part of their professional activities. View Full Information

Research Interests

My laboratory focuses on merging advances in molecular biology with those in biomedical imaging to advance the new field of molecular imaging. Methods to image gene expression in living subjects have been developed. Newer approaches to image fundamental cellular events with optical and radiolabeled probes are under active investigation. These imaging approaches are expected to have a fundamental impact in the study of cancer biology, as well as in molecular therapeutics including gene therapy

Clinical Trials

• 18 F-fluoride PET/CT versus 99Tc-MDP Scanning for Detecting Bone Metastases Recruiting
• Combined F18 and F18 FDG PET/CT for Evaluation of Malignancy Recruiting
• PET/CT and Whole-Body MRI for Detection of Skeletal and Soft Tissue Metastases Recruiting
• Assessing the suitability of an imaging probe for use in clinical cell and gene therapy trials in cancer and rheumatoid arthritis No longer recruiting
• Comparison of I-124 PET/CT, F-18 FDG PET/CT & I-123 whole body scintigraphy for recurrent thyroid CA No longer recruiting

Publications

• Comparison of optical bioluminescence reporter gene and superparamagnetic iron oxide MR contrast agent as cell markers for noninvasive imaging of cardiac cell transplantation. Chen IY, Greve JM, Gheysens O, Willmann JK, Rodriguez-Porcel M, Chu P, Sheikh AY, Faranesh AZ, Paulmurugan R, Yang PC, Wu JC, Gambhir SS. Mol Imaging Biol. 2009 May-Jun; 11 (3): 178-87
• Molecular imaging of phosphorylation events for drug development. Chan CT, Paulmurugan R, Reeves RE, Solow-Cordero D, Gambhir SS. Mol Imaging Biol. 2009 May-Jun; 11 (3): 144-58
• Simulations of virtual PET/CT 3-D bronchoscopy imaging using a physical porcine lung-heart phantom. Yerushalmi D, Mullick R, Quon A, Fahrig R, Pelc NJ, Fann JI, Gambhir SS. Mol Imaging Biol. 2009 Jul-Aug; 11 (4): 275-82
• Protein-functionalized synthetic antiferromagnetic nanoparticles for biomolecule detection and magnetic manipulation. Fu A, Hu W, Xu L, Wilson RJ, Yu H, Osterfeld SJ, Gambhir SS, Wang SX. Angew Chem Int Ed Engl. 2009; 48 (9): 1620-4
• Endogenous NIS expression in triple-negative breast cancers. Renier C, Yao C, Goris M, Ghosh M, Katznelson L, Nowles K, Gambhir SS, Wapnir I. Ann Surg Oncol. 2009; 16 (4): 962-8