Teri Klein
Academic Appointments
- Sr Research Engineer (PI Waiver), Genetics
Key Documents
Contact Information
- Contact Information
Personal Information Email Tel (650) 736-0156Alternate Contact Tiffany Murray Email Tel Work 650-725-0659
Professional Overview
Current Role at Stanford
Director of the PharmGKB
Member of the BioMedical Informatics Executive Committee
Professional Education
| B.A.: | UC Santa Cruz, Chemistry/Biology (1980) |
| Ph.D.: | UC San Francisco, Medical Information Sciences (1987) |
Graduate & Fellowship Program Affiliations
Community and International Work
- PharmGKB Director, 1501 S. California Avenue, Palo Alto, CA 94304
- Co-founder, Pacific Symposium on Biocomputing, International
Scientific Focus
Current Research Interests
My research interests extend over the broad spectrum of pharmacogenetics, computational biology and bioinformatics. Applications include the development of a pharmcogenetics knowledge base, structure-function relationships, de novo modeling and the structural basis of disease. .
My current research areas involve the studies of the following:
* development of an integrated knowledge base about how variation in human genetics leads to variation in our response to drugs
* the stability of the collagen triple helix
* the relationship and prediction of lethal mutations for the genetic collagenous disease Osteogenesis imperfecta
Publications
- Clinical implementation of pharmacogenetics: more than one gene at a time. Clin Pharmacol Ther. 2013; (5): 384-5
- Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for codeine therapy in the context of cytochrome P450 2D6 (CYP2D6) genotype. Clin Pharmacol Ther. 2012; (2): 321-6
- Clopidogrel: a case for indication-specific pharmacogenetics. Clin Pharmacol Ther. 2012; (5): 774-6
- Pharmacogenomics knowledge for personalized medicine. Clin Pharmacol Ther. 2012; (4): 414-7
- CPIC: Clinical Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research Network. Clin Pharmacol Ther. 2011; (3): 464-7
- Clinical assessment incorporating a personal genome. Lancet. 2010; (9725): 1525-35
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