Pehr Harbury
Academic Appointments
- Associate Professor, Biochemistry
- Member, Bio-X
- Member, Cancer Center
Scientific Focus
Research Interests
Our lab engineers proteins and small-molecule drugs at atomic resolution through a combination of structural calculations and combinatorial library synthesis. Our goal is to elucidate predictive principles by which novel shapes and catalytic properties can be conferred accurately on designed polypeptides.
Publications
- Remeasuring the double helix. "Science" 2008 ; 5900 446-9
- Chemical evolution as a tool for molecular discovery. "Annu Rev Biochem" 2007 : 331-49
- Potential energy functions for protein design. "Curr Opin Struct Biol" 2007 ; 2 199-204
- Misincorporation proton-alkyl exchange (MPAX): engineering cysteine probes into proteins. "Curr Protoc Protein Sci" 2005 : Unit26.1
- DNA display I. Sequence-encoded routing of DNA populations. "PLoS Biol" 2004 ; 7 E173
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