Edward Graves
Academic Appointments
- Associate Professor, Radiation Oncology - Radiation Physics
- Member, Stanford Cancer Institute
- Member, Bio-X
- Associate Professor (By courtesy), Radiology - Diagnostic Radiology
Key Documents
Contact Information
- Academic Offices
Personal Information Email Tel (650) 723-5591Alternate Contact Becky Greenberg Administrative Assistant Email Tel Work (650) 498-4005
Professional Overview
Professional Education
| B.S.: | UC Berkeley, Bioengineering (1996) |
| Ph.D.: | UC Berkeley/UCSF, Bioengineering (2001) |
Graduate & Fellowship Program Affiliations
Internet Links
Scientific Focus
Current Research Interests
My research group is focused on applications of emerging functional and molecular imaging techniques in radiation therapy of cancer. In order to integrate these novel imaging procedures with state-of-the-art radiation therapy, a number of issues must be addressed. First, what are the molecular targets that hold the most promise for targeting and monitoring response to radiation therapy, and how can they best be visualized in vivo? Second, what are the limitations of novel imaging techniques that may bear on their application in radiation oncology? Third, how can one display, analyze, and segment multiple three-dimensional datasets to generate target volumes for radiotherapy? And finally, how will the information contained in imaging results of different modalities be integrated into the selection of a treatment course for a patient and subsequently, where appropriate, the specification of an optimized radiation target? These questions comprise my research. Projects that address these topics include the implementation and evaluation of clinical PET/CT imaging for radiation treatment planning, development and validation of novel molecular imaging methods for preclinical and clinical imaging of tumor radiosensitivity and radiation response, development of software for multimodal image analysis, and study of tumor hypoxia and radioresistance in small animal models using a multimodality molecular imaging approach.
Publications
- Development of a micro-computed tomography-based image-guided conformal radiotherapy system for small animals. Int J Radiat Oncol Biol Phys. 2010; (1): 297-305
- Hypoxia in models of lung cancer: implications for targeted therapeutics. Clin Cancer Res. 2010; (19): 4843-52
- RT_Image: an open-source tool for investigating PET in radiation oncology. Technol Cancer Res Treat. 2007; (2): 111-21
- Cost-effectiveness landscape analysis of treatments addressing xerostomia in patients receiving head and neck radiation therapy. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013
- Metabolic tumor volume predicts disease progression and survival in patients with squamous cell carcinoma of the anal canal. J Nucl Med. 2013; (1): 27-32
- Metabolic imaging metrics correlate with survival in early stage lung cancer treated with stereotactic ablative radiotherapy. Lung Cancer. 2012; (3): 219-24
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