Point Spread Function modeling for PET

This research topic investigates the spatially-varying relationship between the biodistribution of the PET tracer in the subject and the measured coincidence counts, represented by the point spread function (PSF). The PSF models are based on theoretical derivation, analytical approximation, computer simulation, or experimental measurements. The derived PSF models are incorporated into the iterative image reconstruction process, with the goal to improve image quality, contrast, and quantitative accuracy.

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