CHRI Seminar: Nanoparticles for Pediatric Cancer Imaging and Therapy

Jun 04, 2018 (Mon) | 11:45 AM -12:45 PM

Center for Clinical Sciences Research (CCSR), Room # 4205 : Stanford, CA

Clinical contrast agents for MRI, which contain gadolinium, have been associated with nephrogenic sclerosis and gadolinium deposition in the brain. Therefore, a search for alternatives is currently underway. Ferumoxytol, an iron supplement, is FDA approved for the treatment of anemia and has been used by our group “off label” as an MR contrast agent. This presentation will provide an overview of the use of ferumoxytol nanoparticles for pediatric cancer imaging with MRI and PET/MRI, including safety data acquired in children thus far. Our team recently demonstrated unique enhancement properties of nanoparticles in pediatric cancers, providing an immediate, non-invasive imaging test to track innate immune responses from macrophages in patients.

Department: Stanford Maternal and Child Health Research Institute

Contact: Roxanna Van Norman | 6504985444 | roxannav@stanford.edu

Presenter(s):

Heike Daldrup-Link, MD Professor, Dept. of Radiology
Suchismita Mohanty, PhD Research Scientist, Dept. of Radiology

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