Stanford Bio-X Frontiers in Interdisciplinary Biosciences Seminar, "Sugary coats: Diverse mechanisms of complex carbohydrate secretion"

Feb 14, 2019 (Thu) | 4:00 PM -5:00 PM
James H. Clark Center, 318 Campus Drive, Seminar Room S360 : Stanford, CA

Refreshments served at 3:45PM; seminar begins at 4:00PM. All living systems produce complex carbohydrates as an energy source, protective coat, or adhesive for cell attachment. Polysaccharides displayed on the cell surface are secreted by diverse mechanisms that either directly couple polymer synthesis to export or involve transporters capable of moving high molecular weight polymers across the plasma membrane. Microbial cellulose biosynthesis and the ABC transporter-mediated secretion of O-antigens exemplify two different mechanisms. Both contribute to the formation of protective coats produced by microbial pathogens to reduce the efficacy of their hosts’ innate immune responses. We obtained detailed insights into detailed insights into diverse polysaccharide translocation mechanisms.

Department:  BioX

Contact: Cici Huber | 6507257472 | chuber@stanford.edu

Presenter(s):

  • Jochen Zimmer Assoc Prof of Molecular Physiology & Biological Physics, UVA

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