Inclusion Criteria:

   1. Ability to understand and the willingness to sign a written informed consent document

   2. Individuals with the following family phenotype and age:

      1. Two or more relatives with pancreatic adenocarcinomas (PDAC) on the same side of
      the family, where two PDAC-affected individuals are first degree related (FDR) +
      at least one PDAC-affected individual is a FDR of the Participant (≥50 years old
      OR 10 years before onset in family)

      2. Two affected FDR with PDAC (≥50 years old OR 10 years before onset of an FDR)

      3. Any of BRCA1, BRCA2, PALB2, ATM mutations confirmed pathogenic or likely
      pathogenic + one FDR or secondary degree related (SDR) with PDAC (≥50 years old
      OR 10 years before onset of an FDR and SDR)

      4. Familial atypical multiple mole-melanoma (FAMMM) with confirmed pathogenic or
      likely pathogenic mutation variants in: p16, CDKN2A (≥50 years old)

      5. Known mutation carrier for STK11 (Peutz Jeghers Syndrome) (≥35 years old)

      6. Lynch syndrome (HNPCC) with confirmed pathogenic or likely pathogenic variants
      in: MLH1, MSH2, MSH6, PMS2, or EPCAM + one FDR or SDR with PDAC (≥50 years old OR
      10 years before onset of an FDR or SDR)

      7. Hereditary pancreatitis with confirmed PRSS1 pathogenic or likely pathogenic
      history of pancreatitis (≥40 years old)

Exclusion Criteria:

None