Cancer Biology of Retinoblastoma

Many children with the childhood cancer, Retinoblastoma, have surgery to remove the tumor and sometimes the entire eye. The purpose of this study is to collect the extra tissue from patients who undergo tumor removal for laboratory experiments that will help us understand not only what occurs in retinoblastoma cells but also how cells normally function. Some of these studies will include an evaluation of how cells control the way that genes are expressed, how cells "know" to become retinal cells, how cells remain retinal cells, how cells lose their identity as retinal cells, what changes make retinoblastoma cells different from normal retinal cells, and what changes make some retinoblastomas worse than others.

Stanford is currently not accepting patients for this trial.

Stanford Investigator(s):

Eligibility


Inclusion Criteria:

   - Patient must have retinoblastoma

   - Patient must be receiving biopsy, partial surgical excision of the tumor, complete
   excision of the tumor, or enucleation of the eye as part of their standard care.

   - Parental consent

Exclusion Criteria:

   - Diagnosis other than Retinoblastoma

   - No surgical sampling of tumor is planned as part of standard care

   - Parental preference to not participate.

Ages Eligible for Study

N/A - 5 Years

Genders Eligible for Study

All

Not currently accepting new patients for this trial

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Julien Sage
650-723-5113
Not Recruiting

Our research team includes physicians, residents, medical students, research assistants, and volunteers. Our research topics include medical imaging, device validation,  mobile application development, and pharmaceutical trials.  

Some of the Neuro-Opthalmic concerns we investigate include Multiple Sclerosis, Optic Neuritis, IIH, and ICP.