CTS225 | Stem Cells in Cardiovascular Regenerative Medicine
Class Meeting Time
Tuesdays & Thursdays | 1 hour
Graduate or medical student standing or Instructor approval
Ngan Huang, PhD
Megan Mayerle, PhD
This is a cardiovascular course that meets for 1 hour on Tuesdays and Thursdays. This course will consist of didactic lectures and journal club presentations on the basic principles and translational applications of stem cells for treatment of cardiovascular diseases. These lectures will be given by the course instructors or invited speakers. Another component of the course is peer-to-peer teaching by students-led journal club presentations. To synthesize knowledge gained from the course, the students will prepare a final report in the form of a research proposal.
After completion of this course, the students should expect to:
1) Get broad exposure to basic and translational applications of stem cell research to cardiovascular medicine
2) Read, interpret, and orally present scientific literature
Readings are articles from primary research or review papers and will be available on Canvas. Students are expected to do the required readings ahead of class.
Classes will consist of didactic lectures or journal club presentation. Students are expected to engage with the speakers by asking at least one question per class.
Grades will be calculated using the following criterion:
50% - Attendance & Class Preparation
25% - Journal Club Presentation
25% - Final Report
Attendance and Class Engagement
Attendance at all class sessions is expected and mandatory. You will receive a participation grade based both on attendance as well as engagement in class discussions. If a student misses a class, they must let the instructors know so that an alternative arrangement will be made to make up for the missed class.
Week 1: Introduction to Cardiovascular Anatomy and Basic Biology
Week 2: Introduction to Stem Cells
Week 3: Introduction to Pluripotent Stem Cells
Week 4: Introduction to Adult Stem Cells
Week 5: Potential of Gene Editing for Stem Cell Therapeutics
Week 6: Taking Stem Cell Therapeutics to the Clinics
Week 7: Preclinical Models of Stem Cell Therapeutics
Week 8: Modeling Cardiovascular disease with iPSCs
Week 9: Engineered Cardiovascular Tissues for Regenerative Medicine
Week 10: Bioethicist or TED talks