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Depression, CBT and ACT,CBT for Insomnia
U. S. Department of Veterans Affairs Central Office
Evident Based Psychiatry
Universal and targeted prevention
High school and college students
Treating depression in patients with heart disease
Men, women in Australia who are depressed and have had a heart attack
Anorexia, web-based, family intervention
Teens at risk of AN and their families
Eating disorders, depression
College age women
Dr. Taylor is developing and evaluating innovative electronic and computer-assisted programs to make treatments, proven effective for treating various lifestyle and psychosocial problems, more cost-effective and available. Research projects include the evaluation and development of computer-assisted and other innovative treatments for panic disorder, generalized anxiety disorder, social phobia, depression, eating disorders and cardiovascular risk-reduction. Related studies focus on the nature of anxiety and eating disorders.Dr. Taylor is also developing prevention programs for eating disorders and obesity in college-aged women and in older adolescents. Having identifed risk factors for eating disorders, he is developing and evaluating interactive multimedia interventions assisted with electronic groups and other technologies to help prevent the onset of disorders in high-risk populations. His research group has developed population-based interventions for eating disorders, obesity and healthy weight regulation so that individualized programs can be offered to all participants simultaneously within defined populations. Studies in this research group have demonstrated the efficacy and effectiveness of an inpatient tobacco use cessation program and have demonstrated methods and models for dissemination/implementation in a variety of hospitals.
Harnessing Mobile Technology to Reduce Mental Health Disorders in College Populations
The prevalence of mental health problems among college populations has risen steadily in
recent decades, with one third of today's students struggling with anxiety, depression, or an
eating disorder (ED). Yet, only 20-40% of college students with mental disorders receive
treatment. Inadequacies in mental health care delivery result in prolonged illness, disease
progression, poorer prognosis, and greater likelihood of relapse, highlighting the need for a
new approach for detecting mental health problems and engaging college students in services.
The investigators have developed a transdiagnostic, low-cost mobile health targeted
prevention and intervention platform that uses population-level screening for engaging
college students in tailored services that address common mental health problems. This care
delivery system represents an ideal model given its use of evidence-based mobile programs, a
transdiagnostic approach that addresses comorbid mental health issues, and personalized
screening and intervention to increase service uptake, enhance engagement, and improve
outcomes. Further, this service delivery model harnesses the expertise of an
interdisciplinary team of behavioral scientists, college student mental health scholars,
technology researchers, and health economists. This work bridges the study team's collective
leadership over the past 25 years in successfully implementing a population-based screening
program in more than 160 colleges and demonstrating the effectiveness of Internet-based
programs for targeted prevention and intervention for anxiety, depression, and EDs. Through
this study, Investigators will test the impact of this mobile mental health platform for
service delivery in a large-scale trial across a diverse range of U.S. colleges. Students who
screen positive or at high-risk for clinical anxiety, depression, or EDs (excluding anorexia
nervosa, for which more intensive medical monitoring is warranted) and who are not currently
engaged in mental health services will be randomly assigned to: 1) intervention via the
mobile mental health platform; or 2) referral to usual care (i.e., campus health or
Participants in the study will be enrolled for 2 years and asked to complete surveys at
baseline, 6 weeks, 6 months, and 2 years.
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Internet Weight Control for Bingeing Adolescents
The purpose of this study is to determine if an internet-based intervention designed to
reduce binge eating and improve healthy weight regulation skills will result in reductions in
binge eating and weight loss, or weight maintenance, in overweight adolescents who binge eat.
Stanford is currently not accepting patients for this trial.
For more information, please contact SPECTRUM, .
Biological CVD Risk Factors in Older Depressed Patients
The purpose of this study is to determine if improvements in mood will ameliorate autonomic
dysregulation, HPA dysfunction and typical (e.g. lipids) and atypical risk factors in
depressed patients with elevated cardiovascular risk (CVD). Up to 70, depressed participants
with elevated cardiovascular risk factors were randomized to a cognitive behavioral
intervention (CBT) or a waiting list control (WLC) condition. Twenty non-depressed age and
risk-matched controls will also recruited. Traditional risk factors (e.g. lipids, blood
pressure, heart rate), atypical risk factors (endothelial function, asymmetric
dimethylarginine, C-reactive protein) will be measured pre and post treatment six months
later Subjects will undergo a psychophysiological stress test while cardiovascular physiology
was measured. Salivary cortisol will be measured during the day and during the psychological
stress test. Depressed subjects will be randomized to a 16 week cognitive behavior therapy
intervention or to a wait-list control. It is hypothesized that reduction in mood will be
associated with reduction in typical and atypical risk factors.
Using Technology to Improve Eating Disorders Treatment
The purpose is to evaluate a technologically-enhanced, guided self-help program to reduce
eating disorder outcomes in college-age women.
PTSD Coach App Evaluation
PTSD Coach is a mobile application (app) that aims to teach individuals self-management
strategies for symptoms of Post-traumatic Stress Disorder (PTSD). PTSD is a major public
health concern. Although effective treatments exist, affected individuals face many barriers
to receiving traditional care. As smartphones are now carried by more than half of the U.S.
population, they have the potential to overcome many of these barriers by delivering
self-help interventions on apps. Despite PTSD Coach's use of evidence-based cognitive
behavioral strategies there is still a need to test the effectiveness of the app in managing
PTSD symptoms. This controlled, two-arm, randomized (1:1) trial will evaluate the efficacy,
feasibility and acceptability of PTSD Coach to reduce PTSD symptoms in a community sample of
trauma survivors with PTSD symptoms. After completing an eligibility phone screen or online
screen, individuals who score a 35 or above on the PTSD Checklist (PCL) and consent will
complete a baseline assessment and then be randomized to the PTSD Coach app condition or a
waitlist control group. Additionally, those assigned to the PTSD Coach intervention will be
instructed to download a research version of the app, called PTSD Explorer, that enables
passive and objective monitoring of app use. Each individual will be reassessed at
post-intervention (3 months) and follow-up (3 months later, or 6 months after completing
baseline). The investigators predict that those using the PTSD Coach app will demonstrate a
significant and sustained reduction in PTSD symptoms and increase in patient coping
self-efficacy compared to the waitlist control group. The investigators will explore if there
is a relationship between levels of engagement and PTSD symptom change.
Testing an Internet-Based Intervention for Preventing Eating Disorders
This study will examine the ability of an Internet-based program to prevent college-aged
women from developing eating disorders.
Promoting Healthy Weight With 'Stability Skills First'
Losing weight has many health benefits for women such as reducing the risk of heart attacks,
high blood pressure, diabetes, and cancer. However, women often struggle with maintaining the
weight they have lost. This may be because they need to learn skills for maintaining weight,
not just losing weight.
When is the optimal time is to learn these maintenance skills? It may be better to lose
weight first and then learn maintenance skills since people may feel good about the weight
they have lost and be motivated to maintain. Alternatively, it may be better to learn
maintenance skills first and then lose weight since they may experience how easy it is to use
these maintenance skills and become confident they can maintain a weight loss in the future.
Therefore, this study will examine whether learning these maintenance skills--before or after
losing weight--helps women succeed at maintaining weight loss.
Stanford is currently not accepting patients for this trial.
For more information, please contact Michaela Kiernan, .