Welcome to the James Lab

The primary aim of the James Lab is to improve the diagnosis and treatment of brain diseases by developing translational molecular imaging agents for visualizing neuroimmune interactions underlying conditions such as Alzheimer’s disease, multiple sclerosis, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, and stroke. We are researching how the brain and its resident immune cells interact with the peripheral immune system at very early, through to late, stages of disease. Our approach involves the discovery and characterization of clinically relevant immune cell biomarkers, followed by the design of imaging agents specifically targeting these biomarkers. After preclinical validation, we translate promising imaging probes to the clinic to enable precision targeting of immunomodulatory therapeutics and real-time monitoring of treatment response.

Make a Gift

Our research is contingent on the continuous support we receive. Please consider making a contribution to the James Lab to help improve the diagnosis and treatment of brain diseases. All gifts are tax deductible as Stanford University is a non-profit organization.

To donate, select "Stanford Medicine (Other)" in the drop-down menu and designate the "James Lab" under Special Instructions.

Watch our JoVE video: PET Imaging of Neuroinflammation Using [11C]DPA-713 in a Mouse Model of Ischemic Stroke