April 2015 Member Publications

1.     New mechanism-based approaches to ablating persistent AF - will drug therapy soon be obsolete? Zaman JA, Baykaner T, Narayan SM. J Cardiovasc Pharmacol. 2015 Apr 25.

2.     Correction of human phospholamban R14del mutation associated with cardiomyopathy using targeted nucleases and combination therapy. Karakikes I, Stillitano F, Nonnenmacher M, Tzimas C, Sanoudou D, Termglinchan V, Kong CW, Rushing S, Hansen J, Ceholski D, Kolokathis F, Kremastinos D, Katoulis A, Ren L, Cohen N, Gho JM, Tsiapras D, Vink A, Wu JC, Asselbergs FW, Li RA, Hulot JS, Kranias EG, Hajjar RJ. Nat Commun. 2015 Apr 29;6:6955.

3.     Development and Evaluation of Standardized Narrative Cases Depicting the General Surgery Professionalism Milestones. Rawlings A, Knox AD, Park YS, Reddy S, Williams SR, Issa N, Jameel A, Tekian A. Acad Med. 2015 Apr 24.

4.     Altering the concentration of silica tunes the functional properties of collagen-silica composite scaffolds to suit various clinical requirements. Perumal S, Ramadass SK, Gopinath A, Madhan B, Shanmugam G, Rajadas J, Mandal AB. J Mech Behav Biomed Mater. 2015 Apr 9.

5.     The genetic basis of peripheral arterial disease: current knowledge, challenges, and future directions. Kullo IJ, Leeper NJ. Circ Res. 2015 Apr 24;116(9):1551-60.

6.     Cis Regulatory Effects on A-to-I RNA Editing in Related Drosophila Species. Sapiro AL, Deng P, Zhang R, Li JB. Cell Rep. 2015 Apr 21.

7.     Induced pluripotent stem cells. Wilson KD, Wu JC. JAMA. 2015 Apr 28;313(16):1613-4.

8.     Meniscus is more susceptible than cartilage to catabolic and anti-anabolic effects of adipokines. Nishimuta JF, Levenston ME. Osteoarthritis Cartilage. 2015 Apr 23.

9.     Electrocardiographic effects of class 1 selective histone deacetylase inhibitor romidepsin. Sager PT, Balser B, Wolfson J, Nichols J, Pilot R, Jones S, Burris HA. Cancer Med. 2015 Apr 27.

10.   Heterogeneous growth-induced prestrain in the heart. Genet M, Rausch MK, Lee LC, Choy S, Zhao X, Kassab GS, Kozerke S, Guccione JM, Kuhl E. J Biomech. 2015 Apr 3.

11.   Increasing aminoterminal-pro-B-type natriuretic peptide precedes the development of arterial hypertension: the multiethnic study of atherosclerosis. Sanchez OA, Jacobs DR Jr, Bahrami H, Peralta CA, Daniels LB, Lima JA, Maisel A, Duprez DA. J Hypertens. 2015 May;33(5):966-74.

12.   Microfluidic analysis of extracellular matrix-bFGF crosstalk on primary human myoblast chemoproliferation, chemokinesis, and chemotaxis. Ferreira MM, Dewi RE, Heilshorn SC. Integr Biol (Camb). 2015 Apr 24.

13.   64Cu-Labeled Divalent Cystine Knot Peptide for Imaging Carotid Atherosclerotic Plaques. Jiang L, Tu Y, Kimura R, Habte F, Chen H, Cheng K, Shi H, Gambhir SS, Cheng Z. J Nucl Med. 2015 Apr 23.

14.   Risk of Cardiovascular Events Associated with Current Exposure to HIV Antiretroviral Therapies in a US Veteran Population. Desai M, Joyce V, Bendavid E, Olshen RA, Hlatky M, Chow A, Holodniy M, Barnett P, Owens DK. Clin Infect Dis. 2015 Apr 22.

15.   Analog electro-optical readout of SiPMs achieves fast timing required for time-of-flight PET/MR. Bieniosek MF, Levin CS. Phys Med Biol. 2015 May 7;60(9):3795-806.

16.   Protein microarrays: a new tool for the study of autoantibodies in immunodeficiency. Rosenberg JM, Utz PJ. Front Immunol. 2015 Apr 7;6:138.

17.   Segmental Aortic Stiffening Contributes to Experimental Abdominal Aortic Aneurysm Development. Raaz U, Zöllner AM, Schellinger IN, Toh R, Nakagami F, Brandt M, Emrich FC, Kayama Y, Eken S, Adam M, Maegdefessel L, Hertel T, Deng A, Jagger A, Buerke M, Dalman RL, Spin JM, Kuhl E, Tsao PS. Circulation. 2015 Apr 22.

18.   Opinion: Sex inclusion in basic research drives discovery. Klein SL, Schiebinger L, Stefanick ML, Cahill L, Danska J, de Vries GJ, Kibbe MR, McCarthy MM, Mogil JS, Woodruff TK, Zucker I. Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):5257-8.

19.   Inhaled β2-Agonist Therapy Increases Functional Residual Capacity in Mechanically Ventilated Children With Respiratory Failure. Ramsi MA, Henry M, Milla CE, Cornfield DN. Pediatr Crit Care Med. 2015 Apr 21.

20.   Dissecting human gene functions regulating islet development with targeted gene transduction. Pauerstein PT, Sugiyama T, Stanley SE, McLean GW, Wang J, Martín MG, Kim SK. Diabetes. 2015 Apr 21.

21.   High-dimensional immune profiling of total and rotavirus VP6-specific intestinal and circulating B cells by mass cytometry. Nair N, Newell EW, Vollmers C, Quake SR, Morton JM, Davis MM, He XS, Greenberg HB. Mucosal Immunol. 2015 Apr 22.

22.   Neurotoxicity of generic anesthesia agents in infants and children: an orphan research question in search of a sponsor. Psaty BM, Platt R, Altman RB. JAMA. 2015 Apr 21;313(15):1515-6.

23.   Vascularized and Complex Organ Buds from Diverse Tissues via Mesenchymal Cell-Driven Condensation. Takebe T, Enomura M, Yoshizawa E, Kimura M, Koike H, Ueno Y, Matsuzaki T, Yamazaki T, Toyohara T, Osafune K, Nakauchi H, Yoshikawa HY, Taniguchi H. Cell Stem Cell. 2015 Apr 15.

24.   Technologies to Measure and Modify Physical Activity and Eating Environments. King AC, Glanz K, Patrick K. Am J Prev Med. 2015 May;48(5):630-638.

25.   A Real-Time Clinical Endoscopic System for Intraluminal, Multiplexed Imaging of Surface-Enhanced Raman Scattering Nanoparticles. Garai E, Sensarn S, Zavaleta CL, Loewke NO, Rogalla S, Mandella MJ, Felt SA, Friedland S, Liu JT, Gambhir SS, Contag CH. PLoS One. 2015 Apr 29;10(4):e0123185.

26.   Food and Physical Activity Environments: An Energy Balance Approach for Research and Practice. Economos CD, Hatfield DP, King AC, Ayala GX, Ann Pentz M. Am J Prev Med. 2015 May;48(5):620-629.

27.   Fact versus artifact: avoiding erroneous estimates of sulfated glycosaminoglycan content using the dimethylmethylene blue colorimetric assay for tissue-engineered constructs. Zheng CH, Levenston ME. Eur Cell Mater. 2015 Apr 19;29:224-36; discussion 236.

28.   T-cell metabolism in autoimmune disease. Yang Z, Matteson EL, Goronzy JJ, Weyand CM. Arthritis Res Ther. 2015 Feb 11;17(1):29.

29.   Naive T Cell Maintenance and Function in Human Aging. Goronzy JJ, Fang F, Cavanagh MM, Qi Q, Weyand CM. J Immunol. 2015 May 1;194(9):4073-4080. Review.

30.   Cellular mechanisms of alveolar pathology in childhood interstitial lung diseases: current insights from mouse genetics. Kuo CS, Desai TJ. Curr Opin Pediatr. 2015 Apr 17.

31.   MicroRNA-mediated regulation of differentiation and trans-differentiation in stem cells. Ong SG, Lee WH, Kodo K, Wu JC. Adv Drug Deliv Rev. 2015 Apr 14.

32.   Skin fibrosis. Identification and isolation of a dermal lineage with intrinsic fibrogenic potential. Rinkevich Y, Walmsley GG, Hu MS, Maan ZN, Newman AM, Drukker M, Januszyk M, Krampitz GW, Gurtner GC, Lorenz HP, Weissman IL, Longaker MT. Science. 2015 Apr 17;348(6232):aaa2151.

33.   Are adaptive randomised trials or non-randomised studies the best way to address the Ebola outbreak in west Africa? Lanini S, Zumla A, Ioannidis JP, Caro AD, Krishna S, Gostin L, Girardi E, Pletschette M, Strada G, Baritussio A, Portella G, Apolone G, Cavuto S, Satolli R, Kremsner P, Vairo F, Ippolito G. Lancet Infect Dis. 2015 Apr 13.

34.   Emergent Salvage Direct Intrahepatic Portocaval Shunt Procedure for Acute Variceal Hemorrhage. Ward TJ, Techasith T, Louie JD, Hwang GL, Hofmann LV, Sze DY. J Vasc Interv Radiol. 2015 Apr 13.

35.   Percutaneous tricuspid valve implantation: two-center experience with midterm results. Eicken A, Schubert S, Hager A, Hörer J, McElhinney DB, Hess J, Ewert P, Berger F. Circ Cardiovasc Interv. 2015 Apr;8(4).

36.   Feasibility of Extended Ambulatory Electrocardiogram Monitoring to Identify Silent Atrial Fibrillation in High-risk Patients: The Screening Study for Undiagnosed Atrial Fibrillation (STUDY-AF). Turakhia MP, Ullal AJ, Hoang DD, Than CT, Miller JD, Friday KJ, Perez MV, Freeman JV, Wang PJ, Heidenreich PA. Clin Cardiol. 2015 Apr 14.

37.   NOTCH1 regulates matrix gla protein and calcification gene networks in human valve endothelium. White MP, Theodoris CV, Liu L, Collins WJ, Blue KW, Lee JH, Meng X, Robbins RC, Ivey KN, Srivastava D. J Mol Cell Cardiol. 2015 Apr 12;84:13-23.

38.   Site-level variation in and practices associated with dabigatran adherence. Shore S, Ho PM, Lambert-Kerzner A, Glorioso TJ, Carey EP, Cunningham F, Longo L, Jackevicius C, Rose A, Turakhia MP. JAMA. 2015 Apr 14;313(14):1443-50.

39.   Intermediate Outcomes in the Prospective, Multicenter Coarctation of the Aorta Stent Trial (COAST). Meadows J, Minahan M, McElhinney DB, McEnaney K, Ringel R; COAST Investigators. Circulation. 2015 Apr 13.

40.   Derivation of Highly Purified Cardiomyocytes from Human Induced Pluripotent Stem Cells Using Small Molecule-modulated Differentiation and Subsequent Glucose Starvation. Sharma A, Li G, Rajarajan K, Hamaguchi R, Burridge PW, Wu SM. J Vis Exp. 2015 Mar 18;(97).

41.   Levosimendan displays anti-inflammatory effects and decreases MPO bioavailability in patients with severe heart failure. Adam M, Meyer S, Knors H, Klinke A, Radunski UK, Rudolph TK, Rudolph V, Spin JM, Tsao PS, Costard-Jäckle A, Baldus S. Sci Rep. 2015 Apr 13;5:9704.

42.   Clinical trial management of participant recruitment, enrollment, engagement, and retention in the SMART study using a Marketing and Information Technology (MARKIT) model. Gupta A, Calfas KJ, Marshall SJ, Robinson TN, Rock CL, Huang JS, Epstein-Corbin M, Servetas C, Donohue MC, Norman GJ, Raab F, Merchant G, Fowler JH, Griswold WG, Fogg BJ, Patrick K. Contemp Clin Trials. 2015 Apr 10;42:185-195.

43.   A "Repair-All" Strategy for Degenerative Mitral Valve Disease Safely Minimizes Unnecessary Replacement. Goldstone AB, Cohen JE, Howard JL, Edwards BB, Acker AL, Hiesinger W, MacArthur JW Jr, Atluri P, Woo YJ. Ann Thorac Surg. 2015 Apr 9.

44.   Cardiopulmonary Responses and Prognosis in Hypertrophic Cardiomyopathy: A Potential Role for Comprehensive Noninvasive Hemodynamic Assessment. Finocchiaro G, Haddad F, Knowles JW, Caleshu C, Pavlovic A, Homburger J, Shmargad Y, Sinagra G, Magavern E, Wong M, Perez M, Schnittger I, Myers J, Froelicher V, Ashley EA. JACC Heart Fail. 2015 Mar 30.

45.   BMPR2 Preserves Mitochondrial Function and DNA during Reoxygenation to Promote Endothelial Cell Survival and Reverse Pulmonary Hypertension. Diebold I, Hennigs JK, Miyagawa K, Li CG, Nickel NP, Kaschwich M, Cao A, Wang L, Reddy S, Chen PI, Nakahira K, Alcazar MA, Hopper RK, Ji L, Feldman BJ, Rabinovitch M. Cell Metab. 2015 Apr 7;21(4):596-608.

46.   A Thermo-sensitive Delivery Platform for Topical Administration of Inflammatory Bowel Disease Therapies. Sinha SR, Nguyen LP, Inayathullah M, Malkovskiy A, Habte F, Rajadas J, Habtezion A. Gastroenterology. 2015 Apr 8.

47.   Sca-1+ cells from fetal heart with high aldehyde dehydrogenase activity exhibit enhanced gene expression for self-renewal, proliferation, and survival. Dey D, Pan G, Varma NR, Palaniyandi SS. Oxid Med Cell Longev. 2015;2015:730683.

48.   Adipose Triglyceride Lipase, Not Hormone-Sensitive Lipase, Is the Primary Lipolytic Enzyme in Fasting Elephant Seals (Mirounga angustirostris). Fowler MA, Costa DP, Crocker DE, Shen WJ, Kraemer FB. Physiol Biochem Zool. 2015 May-Jun;88(3):284-94.

49.   The epidemiological advantage of preferential targeting of tuberculosis control at the poor. Andrews JR, Basu S, Dowdy DW, Murray MB. Int J Tuberc Lung Dis. 2015 Apr;19(4):375-80.

50.   Optical control of biological processes by light-switchable proteins. Fan LZ, Lin MZ. Wiley Interdiscip Rev Dev Biol. 2015 Apr 8.

51.   Scintillating-Balloon-Enabled Fiber-Optic System for Radionuclide Imaging of Atherosclerotic Plaques. Zaman RT, Kosuge H, Carpenter C, Sun C, McConnell MV, Xing L. J Nucl Med. 2015 Apr 9.

52.   Association of spontaneous bleeding and myocardial infarction with long-term mortality after percutaneous coronary intervention. Kazi DS, Leong TK, Chang TI, Solomon MD, Hlatky MA, Go AS. J Am Coll Cardiol. 2015 Apr 14;65(14):1411-20.

53.   Prototype positron emission tomography insert with electro-optical signal transmission for simultaneous operation with MRI. Olcott P, Kim E, Hong K, Lee BJ, Grant AM, Chang CM, Glover G, Levin CS. Phys Med Biol. 2015 May 7;60(9):3459-78.

54.   Effect of Tricuspid Regurgitation and the Right Heart on Survival After Transcatheter Aortic Valve Replacement: Insights From the Placement of Aortic Transcatheter Valves II Inoperable Cohort. Lindman BR, Maniar HS, Jaber WA, Lerakis S, Mack MJ, Suri RM, Thourani VH, Babaliaros V, Kereiakes DJ, Whisenant B, Miller DC, Tuzcu EM, Svensson LG, Xu K, Doshi D, Leon MB, Zajarias A. Circ Cardiovasc Interv. 2015 Apr;8(4).

55.   Late breaking trials of 2014 in coronary artery disease: Commentary covering ACC, EuroPCR, SCAI, TCT, ESC, and AHA. Tremmel JA, Bhatt DL, Pinto DS, Grines CL. Catheter Cardiovasc Interv. 2015 Apr 9.

56.   Elafin Reverses Pulmonary Hypertension via Caveolin-1 Dependent Bone Morphogenetic Protein Signaling. Nickel NP, Spiekerkoetter E, Gu M, Li CG, Li H, Kaschwich M, Diebold I, Hennigs JK, Kim KY, Miyagawa K, Wang L, Cao A, Sa S, Jiang X, Stockstill RW, Nicolls MR, Zamanian RT, Bland RD, Rabinovitch M. Am J Respir Crit Care Med. 2015 Apr 8.

57.   Editorial comment on paper by Naguib, et al. 'A single-center strategy to minimize blood transfusion in neonates and children undergoing cardiac surgery'. Williams GD, Ramamoorthy C. Paediatr Anaesth. 2015 May;25(5):442-4.

58.   Carboxypeptidase B2 Deficiency Reveals Opposite Effects of Complement C3a and C5a in a Murine Polymicrobial Sepsis Model. Shao Z, Nishimura T, Leung LL, Morser J. J Thromb Haemost. 2015 Apr 7.

59.   A dynamic picture of protein behavior in cells. Teruel MN, Gu B, Zhao ML. Nat Biotechnol. 2015 Apr 7;33(4):356-7.

60.   An ultrafast rechargeable aluminium-ion battery. Lin MC, Gong M, Lu B, Wu Y, Wang DY, Guan M, Angell M, Chen C, Yang J, Hwang BJ, Dai H. Nature. 2015 Apr 16;520(7547):325-8.

61.   Lowering the B1 threshold for improved BEAR B1 mapping. Jordanova KV, Nishimura DG, Kerr AB. Magn Reson Med. 2015 Apr 4.

62.   Reply. Atluri P, Woo YJ. Ann Thorac Surg. 2015 Apr;99(4):1489.

63.   Invited commentary. Woo YJ. Ann Thorac Surg. 2015 Apr;99(4):1412-3.

64.   Using SRM-MS to quantify nuclear protein abundance differences between adipose tissue depots of insulin-resistant mice. Ota A, Kovary KM, Wu OH, Ahrends R, Shen WJ, Costa MJ, Feldman BJ, Kraemer FB, Teruel MN. J Lipid Res. 2015 May;56(5):1068-78.

65.   Semiquantitative Analysis of the Biodistribution of the Combined 18F-NaF and 18F-FDG Administration for PET/CT Imaging. Minamimoto R, Mosci C, Jamali M, Barkhodari A, Habte F, Jackson T, Mittra E, Gambhir SS, Iagaru A. J Nucl Med. 2015 May;56(5):688-94.

66.   Gene expression profiling to study racial differences after heart transplantation. Khush KK, Pham MX, Teuteberg JJ, Kfoury AG, Deng MC, Kao A, Anderson AS, Cotts WG, Ewald GA, Baran DA, Hiller D, Yee J, Valantine HA. J Heart Lung Transplant. 2015 Feb 7.

67.   'Velcro' engineering of high-affinity CD47 Ectodomain as SIRPα antagonists that enhance antibody-dependent cellular phagocytosis. Ho CC, Guo N, Sockolosky JT, Ring AM, Weiskopf K, Özkan E, Mori Y, Weissman IL, Garcia KC. J Biol Chem. 2015 Apr 2.

68.   Proton pump inhibitors and vascular function: A prospective cross-over pilot study. Ghebremariam YT, Cooke JP, Khan F, Thakker RN, Chang P, Shah NH, Nead KT, Leeper NJ. Vasc Med. 2015 Apr 2.

69.   Medication adherence and visit-to-visit variability of systolic blood pressure in African Americans with chronic kidney disease in the AASK trial. Hong K, Muntner P, Kronish I, Shilane D, Chang TI. J Hum Hypertens. 2015 Apr 2.

70.   Propensity-Matched Comparisons of Clinical Outcomes after Transapical or Transfemoral TAVR: A PARTNER-I Trial Substudy. Blackstone EH, Suri RM, Rajeswaran J, Babaliaros V, Douglas PS, Fearon WF, Miller DC, Hahn RT, Kapadia SR, Kirtane AJ, Kodali SK, Mack M, Szeto WY, Thourani VH, Tuzcu EM, Williams MR, Akin JJ, Leon MB, Svensson LG. Circulation. 2015 Apr 1.

71.   Early reprogramming regulators identified by prospective isolation and mass cytometry. Lujan E, Zunder ER, Ng YH, Goronzy IN, Nolan GP, Wernig M.Nature. 2015 Apr 1.

72.   Reversal of Fibrosis in Chronic Rejection in Mouse Airways through Combined Relaxin and Lysyl Oxidase Inhibitor Therapy. Lin YC, Jiang X, Nicolls MR. Ann Am Thorac Soc. 2015 Mar;12 Suppl 1:S75.

73.   INHERIT (INHibition of the renin angiotensin system in hypertrophic cardiomyopathy and the Effect on hypertrophy-a Randomised Intervention Trial with losartan). Olivotto I, Ashley EA. Glob Cardiol Sci Pract. 2015 Jan 26;2015:7.

74.   Studies in Fat Grafting: Part V. Cell-Assisted Lipotransfer to Enhance Fat Graft Retention is Dose Dependent. Paik KJ, Zielins ER, Atashroo DA, Maan ZN, Duscher D, Luan A, Walmsley GG, Momeni A, Vistnes S, Gurtner GC, Longaker MT, Wan DC. Plast Reconstr Surg. 2015 Mar 17.

75.   50 Is the New 70: Short Ventriculo-Atrial Times Are Common in Children with Atrio-Ventricular Reciprocating Tachycardia. Ceresnak SR, Doan LN, Motonaga KS, Avasarala K, Trela A, Reddy C, Dubin AM. Heart Rhythm. 2015 Mar 27.

76.   Reperfusion of very low cerebral blood volume lesion predicts parenchymal hematoma after endovascular therapy. Mishra NK, Christensen S, Wouters A, Campbell BC, Straka M, Mlynash M, Kemp S, Cereda CW, Bammer R, Marks MP, Albers GW, Lansberg MG; DEFUSE 2 Investigators. Stroke. 2015 May;46(5):1245-9.

77.   Lipoprotein particles and size, total and high molecular weight adiponectin, and leptin in relation to incident coronary heart disease among severely obese postmenopausal women: The Women's Health Initiative Observational Study. Mackey RH, McTigue KM, Chang YF, Barinas-Mitchell E, Evans RW, Tinker LF, Lewis CE, Manson JE, Stefanick ML, Howard BV, Phillips LS, Liu S, Kulick D, Kuller LH. BBA Clin. 2015 Jun;3:243-250.

78.   Theranostic mesoporous silica nanoparticles biodegrade after pro-survival drug delivery and ultrasound/magnetic resonance imaging of stem cells. Kempen PJ, Greasley S, Parker KA, Campbell JL, Chang HY, Jones JR, Sinclair R, Gambhir SS, Jokerst JV. Theranostics. 2015 Mar 1;5(6):631-42.

79.   Organoid modeling for cancer precision medicine. Cantrell MA, Kuo CJ. Genome Med. 2015 Mar 31;7(1):32.

80.   Noninvasive pulmonary nodule elastometry by CT and deformable image registration. Negahdar M, Fasola CE, Yu AS, von Eyben R, Yamamoto T, Diehn M, Fleischmann D, Tian L, Loo BW, Maxim PG. Radiother Oncol. 2015 Mar 27.

81.   Quantitative tracking of passage and 3D culture effects on chondrocyte and fibrochondrocyte gene expression. Son MS, Levenston ME. J Tissue Eng Regen Med. 2015 Mar 30.

82.   Emerging Brain Morphologies from Axonal Elongation. Holland MA, Miller KE, Kuhl E. Ann Biomed Eng. 2015 Mar 31.

83.   Reply to B. O'Sullivan et al. Fakhry C, Zhang Q, Nguyen-Tan PF, Rosenthal D, El-Naggar AK, Garden AS, Soulieres D, Trotti A, Avizonis VN, Ridge JA, Harris J, Le QT, Gillison M. J Clin Oncol. 2015 Mar 30.

84.   Assessing the treatment effect in a randomized controlled trial with extensive non-adherence: the EVOLVE trial. Kubo Y, Sterling LR, Parfrey PS, Gill K, Mahaffey KW, Gioni I, Trotman ML, Dehmel B, Chertow GM. Pharm Stat. 2015 Apr 6.