CVI Manuscript Awards

Each Winter, the Cardiovascular Institute awards authors of outstanding manuscripts published in the previous year. The manuscript must reference the first or last author's affiliation with CVI.

Application deadline: January 22, 2023

2021

Jung-Min Ahn, MD

Visiting Scholar

Microcirculatory Resistance Predicts Allograft Rejection and Cardiac Events After Heart Transplantation
Journal of the American College of Cardiology

Lab of William Fearon, MD

Sara Ranjbarvaziri, PhD

Postdoctoral Fellow, Pediatrics

Altered Cardiac Energetics and Mitochondrial Dysfunction in Hypertrophic Cardiomyopathy
Circulation

Lab of Daniel Bernstein, MD

Dan Li, PhD

Postdoctoral Fellow, Pediatrics

ALDH1A3 Coordinates Metabolism With Gene Regulation in Pulmonary Arterial Hypertension
Circulation

Lab of Marlene Rabinovitch, MD

Mehmet Ozen, PhD

Basic Research Scientist, Radiology / Canary Center

Mitochondria-Rich Extracellular Vesicles Rescue Patient-Specific Cardiomyocytes From Doxorubicin Injury: Insights Into the SENECA Trial
Journals of the American College of Cardiology: CardioOncology

Lab of Utkan Demirci, PhD

2020

2019

Vinicio de Jesus Perez, MD

Activation of the Wnt/Planar Cell Polarity Pathway Is Required for Pericyte Recruitment During Pulmonary Angiogenesis
The American Journal of Pathology

Ke Yuan , Mark E Orcholski , Cristina Panaroni , Eric M Shuffle , Ngan F Huang , Xinguo Jiang , Wen Tian , Eszter K Vladar  5, Lingli Wang  , Mark R Nicolls , Joy Y Wu , Vinicio de Jesus Perez

Lab of Vinicio de Jesus Perez

William Goodyer, MD

Transcriptomic Profiling of the Developing Cardiac Conduction System at Single-Cell Resolution
Circulation Research

William R Goodyer, Benjamin M Beyersdorf, David T Paik, Lei Tian, Guang Li, Jan W Buikema, Orlando Chirikian, Shannon Choi, Sneha Venkatraman, Eliza L Adams, Marc Tessier-Lavigne, Joseph C Wu, Sean M Wu

Lab of Sean M, Wu, MD, PhD

Christoph Olivier, MD

Incidence, Characteristics, and Outcomes of Myocardial Infarction in Patients With Peripheral Artery Disease: Insights From the EUCLID Trial
JAMA Cardiology

Christoph B Olivier, Hillary Mulder, William R Hiatt , W Schuyler Jones, F Gerry R Fowkes, Frank W Rockhold, Jeffrey S Berger , Iris Baumgartner, Peter Held, Brian G Katona, Lars Norgren, Juuso Blomster, Manesh R Patel, Kenneth W Mahaffey

Lab of Kenneth Mahaffey, MD

Joe Zhang, PhD

A Human iPSC Double-Reporter System Enables Purification of Cardiac Lineage Subpopulations with Distinct Function and Drug Response Profiles
Cell Stem Cell

Joe Z Zhang, Vittavat Termglinchan, Ning-Yi Shao, Ilanit Itzhaki, Chun Liu, Ning Ma, Lei Tian, Vicky Y Wang, Alex C Y Chang, Hongchao Guo, Tomoya Kitani, Haodi Wu, Chi Keung Lam, Kazuki Kodo, Nazish Sayed, Helen M Blau, Joseph C Wu

Lab of Joseph C. Wu, MD, PhD

2018

Jingjing Li, PhD

Decoding the Genomics of Abdominal Aortic Aneurysm  
Cell

Li J, Pan C, Zhang S, Spin JM, Deng A, Leung LLK, Dalman RL, Tsao PS, Snyder M

Labs of Michael Snyder, PhD and Phil Tsao, PhD

Ning Ma, PhD

Determining the Pathogenicity of a Genomic Variant of Uncertain Significance Using CRISPR/Cas9 and Human-Induced Pluripotent Stem Cells  
Circulation

Ma N, Zhang JZ, Itzhaki I, Zhang SL, Chen H, Haddad F, Kitani T, Wilson KD, Tian L, Shrestha R, Wu H, Lam CK, Sayed N, Wu JC

Lab of Joseph C. Wu, MD, PhD

Takeshi Nishi, MD

Fractional Flow Reserve and Quality-of-Life Improvement After Percutaneous Coronary Intervention in Patients With Stable Coronary Artery Disease
Circulation

Nishi T, Piroth Z, De Bruyne B, Jagic N, Möbius-Winkler S, Kobayashi Y, Derimay F, Fournier S, Barbato E, Tonino P, Jüni P, Pijls NHJ, Fearon WF

Labs of William F. Fearon and Peter J. Fitzgerald

David Paik, PhD

Large-Scale Single-Cell RNA-Seq Reveals Molecular Signatures of Heterogeneous Populations of Human Induced Pluripotent Stem Cell-Derived Endothelial Cells
Circ Res

Paik DT, Tian L, Lee J, Sayed N, Chen IY, Rhee S, Rhee JW, Kim Y, Wirka RC, Buikema JW, Wu SM, Red-Horse K, Quertermous T, Wu JC.

Lab of Joseph C. Wu, MD, PhD

Darshan Trivedi, PhD

Deciphering the Super Relaxed State of Human β-cardiac Myosin and the Mode of Action of Mavacamten from Myosin Molecules to Muscle Fiber
Proc Natl Acad Sci U S A

Anderson RL, Trivedi DV, Sarkar SS, Henze M, Ma W, Gong H, Rogers CS, Gorham JM, Wong FL, Morck MM, Seidman JG, Ruppel KM, Irving TC, Cooke R, Green EM, Spudich JA.

Lab of James Spudich, PhD

Ke Yuan, PhD

Loss of Endothelium-Derived Wnt5a Is Associated With Reduced Pericyte Recruitment and Small Vessel Loss in Pulmonary Arterial Hypertension    
Circulation 

Yuan K, Shamskhou EA, Orcholski ME, Nathan A, Reddy S, Honda H, Mani V, Zeng Y, Ozen MO, Wang L, Demirci U, Tian W, Nicolls MR, de Jesus Perez VA.

Lab of Vinicio de Jesus Perez, MD

2017

Myriam Amsallem, MD

Right Heart End-Systolic Remodeling Index Strongly Predicts Outcomes in Pulmonary Arterial Hypertension: Comparison With Validated Models
Circ Cardiovasc Imaging

Amsallem M, Sweatt AJ, Aymami MC, Kuznetsova T, Selej M, Lu H, Mercier O, Fadel E, Schnittger I, McConnell MV, Rabinovitch M, Zamanian RT, Haddad F

Labs: Francois Haddad, MD; Roham Zamanian, MD

Yuhei Kobayashi, MD

Agreement of the Resting Distal to Aortic Coronary Pressure With the Instantaneous Wave-Free Ratio
J Am Coll Cardiol

Kobayashi Y, Johnson NP, Zimmermann FM, Witt N, Berry C, Jeremias A, Koo BK, Esposito G, Rioufol G, Park SJ, Nishi T, Choi DH, Oldroyd KG, Barbato E, Pijls NHJ, De Bruyne B, Fearon WF

Lab: William Fearon, MD

Qing Liu, PhD

Genome-Wide Temporal Profiling of Transcriptome and Open Chromatin of Early Cardiomyocyte Differentiation Derived From hiPSCs and hESCs
Circ Res

Liu Q, Jiang C, Xu J, Zhao MT, Van Bortle K, Cheng X, Wang G, Chang HY, Wu JC, Snyder MP

Lab: Michael Snyder, PhD

Mingtao Zhao, PhD

Molecular and functional resemblance of differentiated cells derived from isogenic human iPSCs and SCNT-derived ESCs
Proc Natl Acad Sci USA

Zhao MT, Chen H, Liu Q, Shao NY, Sayed N, Wo HT, Zhang JZ, Ong SG, Liu C, Kim Y, Yang H, Chour T, Ma H, Gutierrez NM, Karakikes I, Mitalipov S, Snyder MP, Wu JC

Lab: Joseph Wu, MD, PhD

2016

Mingxia Gu, PhD

Patient-Specific iPSC-Derived Endothelial Cells Uncover Pathways that Protect against Pulmonary Hypertension in BMPR2 Mutation Carriers.
Cell Stem Cell

Gu M, Shao NY, Sa S, Li D, Termglinchan V, Ameen M, Karakikes I, Sosa G, Grubert F, Lee J, Cao A, Taylor S, Ma Y, Zhao Z, Chappell J, Hamid R, Austin ED, Gold JD, Wu JC, Snyder MP, Rabinovitch M

Kozo Okada, MD

Attenuated-Signal Plaque Progression Predicts Long-Term Mortality After Heart Transplantation: IVUS Assessment of Cardiac Allograft Vasculopathy.
J Am Coll Cardiol

Okada K, Fearon WF, Luikart H, Kitahara H, Otagiri K, Tanaka S, Kimura T, Yock PG, Fitzgerald PJ, Yeung AC, Valantine HA, Khush KK, Honda Y

Fatima Rodriguez, MD, MPH

Association Between Intensity of Statin Therapy and Mortality in Patients With Atherosclerotic Cardiovascular Disease.
JAMA Cardiol

Rodriguez F, Maron DJ, Knowles JW, Virani SS, Lin S, Heidenreich PA

 

Elena Matsa, PhD

Transcriptome Profiling of Patient-Specific Human iPSC-Cardiomyocytes Predicts Individual Drug Safety and Efficacy Responses In Vitro.
Cell Stem Cell

Matsa E, Burridge PW, Yu KH, Ahrens JH, Termglinchan V, Wu H, Liu C, Shukla P, Sayed N, Churko JM, Shao N, Woo NA, Chao AS, Gold JD, Karakikes I, Snyder MP, Wu JC

2015

Alexandre Ribeiro, PhD

Contractility of single cardiomyocytes differentiated from pluripotent stem cells depends on physiological shape and substrate stiffness
Proc Natl Acad Sci U S A

Alexandre J. S. Ribeiro, Yen-Sin Ang, Ji-Dong Fu, Renee N. Rivas, Tamer M. A. Mohamed, Gadryn C. Higgs, Deepak Srivastava, and Beth L. Pruitt

Vahid Serpooshan, PhD

Epicardial FSTL1 reconstitution Regenerates the Adult Mammalian Heart
Nature

Ke Wei, Vahid Serpooshan, Cecilia Hurtado, Marta Diez-Cunado, Mingming Zhao, Sonomi Maruyama, Wenhong Zhu, Giovanni Fajardo, Michela Noseda, Kazuto Nakamura4, Xueying Tian, Qiaozhen Liu, AndrewWang,Yuka Matsuura, Paul Bushway, Wenqing Cai, Alex Savchenko, Morteza Mahmoudi, Michael D. Schneider, Maurice J. B. van den Hoff, Manish J. Butte, Phillip C. Yang, Kenneth Walsh, Bin Zhou, Daniel Bernstein, Mark Mercola & Pilar Ruiz-Lozano

Haodi Wu, PhD

Epigenetic Regulation of Phosphodiesterases 2A and 3A Underlies Compromised β Adrenergic Signaling in an iPSC Model of Dilated Cardiomyopathy
Cell Stem Cell

Haodi Wu, Jaecheol Lee, Ludovic G. Vincent, Qingtong Wang, Mingxia Gu, Feng Lan, Jared M. Churko, Karim I. Sallam, Elena Matsa, Arun Sharma, Joseph D. Gold, Adam J. Engler, Yang K. Xiang, Donald M. Bers, and Joseph C. Wu

Yuhei Kobayashi, MD

The Prognostic Value of Residual Coronary Stenoses After Functionally Complete Revascularization
J Am Coll Cardiol

Yuhei Kobayashi, Chang-Wook Nam, Pim A.L. Tonino, Takumi Kimura, Bernard De Bruyne, Nico H.J. Pijls, William F. Fearon, on behalf of the FAME Study Investigators

2014