April 24, 2017
Li Ka Shing Conference Center

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Advances in research and technology now afford us the unique opportunity to develop and test novel diagnostics and therapeutics. This conference takes advantage of the collective experience and expertise of our speakers in drug discovery. A broad range of policy, research, and venture topics are covered.

Congratulations to our Research Poster Award Winners!

Yu-Wen Alvin Huang | ApoE2, ApoE3 and ApoE4 differentially stimulate amyloid precursor protein transcription and amyloid-beta secretion in human neurons

Wesley L. McKeithan | Use Of patient-derived long QT syndrome type 3 hiPSC cardiomyocytes to develop new anti- arrhythmic therapeutic

Ming-Tao Zhao  Molecular and functional resemblance of terminally differentiated cells derived from isogenic human iPSCs and somatic cell nuclear transfer derived ESCs

Special thanks to our Judges:

Sean Wu, MD PhD

Philip Sager, MD 

Ioannis Karakikes, PhD

Bruch Koch, PhD


Welcome Remarks

Christopher G. Dawes, MBA

President and Chief Executive Officer
Lucille Packard Children’s Hospital 


David Entwistle, MHSA

President and Chief Executive Officer Stanford Health Care


Keynote Speakers

Thomas Sudhof, PhD

2013 Nobel Laureate
Avram Goldstein Professor in the School of Medicine and Professor, by courtesy, of Neurology and of Psychiatry and Behavioral Sciences

Robert Califf, MD

Former Commissioner of U.S. Food and Drug Administration


Bench to Bedside - Cardiovascular Medicine

Eric Olson, PhD

Annie and Willie Nelson Professorship in Stem Cell Research; Pogue Distinguished Chair in Research on Cardiac Birth Defects; The Robert A. Welch Distinguished Chair in Science

Shaun Coughlin, MD, PhD

Distinguished Professorship in Cardiovascular Biology and Medicine, UCSF

Stephen Quake, PhD

Lee Otterson Professor, Stanford School of Engineering; Professor of Bioengineering of Applied Physics and, by courtesy, of Physics; Co-President of the Chan Zuckerberg Biohub

Industry - Promises & Challenges

James Bradner, MD

Novartis Institutes for BioMedical Research

Sean E. Harper, MD

Executive Vice President
Research and Development

David Altshuler, MD, PhD

Executive Vice President, Global Research and Chief Scientific Officer

Andrew Plump, MD, PhD

Chief Medical and Scientific Officer
Takeda Pharmaceuticals

Bench to Bedside - Cancer Therapies

Alan Ashworth, PhD, FRS

Director, UCSF Helen Diller Family Comprehensive Cancer Center; Senior Vice President, Cancer Services, UCSF Health

Gideon Bollag, PhD

Chief Executive Officer, Plexxikon


Shivaani Kummar, MD, FACP

Professor of Medicine (Oncology) and of Radiology (Molecular Imaging Program at Stanford) at the Stanford University Medical Center

Panel Chairs

Helen M. Blau, PhD

The Donald and Delia Baxter Foundation Professor, Stanford
Director, Baxter Laboratory for Stem Cell Biology

Robert A. Harrington, MD

Arthur L. Bloomfield Professor of Medicine
Chair, Stanford Department of Medicine

Beverly S. Mitchell, MD

Director, Stanford Cancer Institute; George E. Becker Professor in Medicine; Professor, by courtesy, of Chemical and Systems Biology

California Institute of Regenerative Medicine

Stephen S. Lin, PhD 

Senior Science Officer, Strategic Infrastructure



Joseph C. Wu, MD, PhD 

Welcome Remarks

Christopher G. Dawes, MBA

David Entwistle, MHSA


Thomas Südhof, MD, PhD | "Why Understanding and Treating Neuropsychiatric Disorders is So Difficult"

Robert Califf, MD, MACC | "Key Elements of the Drug Development Ecosystem"

Bench to Bedside - Cardiovascular Medicine

Shaun R. Coughlin, MD, PhD | "Protease-Activated Receptors: Bench to Bedside to Bench"

Eric Olson, PhD | "Muscle Making and Muscle Breaking: From Developmental Mechanisms to Therapeutics for Heart and Muscle Disease"

Stephen Quake, PhD | "Single Cell Genomics"

Panel Discussion | Chair: Helen M. Blau, PhD

Industry - Promises & Challenges

James (Jay) E. Bradner, MD | "The New Science of Therapeutics"

Sean E. Harper, MD | "Realizing the Promise of Human Genetics in Drug Discovery and Development"

Andrew Plump, MD, PhD | "Innovation Driven Research and Development at Takeda"

David Altshuler, MD, PhD | "Humanizing Drug Discovery"

Panel Discussion | Chair: Robert A. Harrington MD

Bench to Bedside - Cancer Therapies

Alan Ashworth, PhD, FRS | "Synthetic Lethal Approaches to Cancer Therapy"

Gideon Bollag, PhD | "Structure Guided Strategies to Optimize Cancer Therapeutics"

Shivaani Kummar, MD, FACP | "Translating Discoveries to Cures - Designing Early Phase Trials of Anticancer Agents"

Panel Discussion | Chair: Beverly S. Mitchell, MD

California Institute for Regenerative Medicine

Stephen S. Lin, PhD | "Initiatives to Advance Stem Cell Based Drug Discovery and Medicine"

Research Poster Reception & Award


Joseph C. Wu, MD, PhD

Sanjay V. Malhotra, PhD

Mark Mercola, PhD

Supported by

Stanford Cardiovascular Institute

Stanford Cancer Institute

California Institute for Regenerative Medicine