The Ye Lab is currently looking for candidates for the following positions:
1. Lab Technician - Temporary for 1 Year
The Department of Radiation Oncology, Division of Radiation and Cancer Biology, is hiring a Lab Technician to work in the Ye Lab.
A common hallmark of cancer is the modulation of metabolic pathways to reprogram epigenetic landscape and block cell differentiation. Dr. Jiangbin Ye’s professional interest is to investigate the causes and consequences of the abnormal metabolic phenotypes of tumor cells, with the prospect that metabolic intervention approaches might be developed to restore these metabolic pathways to improve differentiation therapy. The lab’s current goal is (1) To explore the complex role of metabolic reprogramming in epigenetic regulations, and how cell fate and differentiation process are controlled by these epigenetic regulations. (2) To identify metabolites from patient samples as biomarkers for cancer early detection and diagnosis.
This candidate will work with other lab members on experiments with cell culture, cell counting, western blot, and education on the operations of lab instruments. The Ye lab has strong expertise on metabolomics studies, so the trainee will also receive trainings on modern metabolomics research tools, including YSI biochemical analyzer, Seahorse XF Analyzer, hypoxia chamber and Agilent Q-TOF LC-MS. The lab is specialized in both untargeted and targeted metabolomics analysis, particularly isotope tracing technique for metabolic flux analysis. Dr. Ye is committed to mentoring and training the candidate and providing support for the candidate to reach their career goal.
Additionally, this candidate will also be involved with weekly lab meetings to learn about experimental design and collaborate with other labs within the department.
This position will be 1-year, temporary position, with start expectation May/June 2023
If you are interested in this role, please submit your application packet to Meg Fuentes, Administrative Associate, via email: firstname.lastname@example.org
Application Packet Requirements:
1. Cover Letter
3. Three References - Names and Contact Information
4-year degree, preferred in Chemistry, Biology, Biochemistry, or related field. Previous wet-lab experience in biomedical research field is preferred.
2. Graduate Students
Graduate position available in Cancer metabolism
An emerging hallmark of cancer is the modulation of metabolic pathways by malignant cells to promote cancer development. Dr. Jiangbin Ye’s professional interest is to investigate the causes and consequences of the abnormal metabolic phenotypes of tumor cells in response to microenvironmental stresses such as hypoxia and nutrient deprivation, with the prospect that therapeutic approaches might be developed to target these metabolic pathways to improve cancer treatment. Dr. Ye’s recent work has established the significance of serine and one-carbon unit metabolism in proliferation and redox regulation in cancer. The lab’s future goal is to explore the complex role of this metabolic pathway in oxidative stress resistance, epigenetic regulation and cell differentiation.
The Ye lab has openings for graduate students at Stanford University. If interested, please contact Dr. Ye to discuss a possible rotation: yej1 at stanford.edu
3. Undergraduate Students
The Ye Lab is seeking a highly motivated Stanford undergraduate college student who is considering a career in science or medicine. Students will have the opportunity to gain research skills and contribute to projects under faculty mentorship. If interested, please contact Dr. Ye at yej1 at stanford.edu and please provide your resume/CV and college transcript.