Inverse Treatment Planning

Development of a principled approach for therapeutic plan optimization is critical for the success of radiation therapy. The inverse planning problem is at the intersection of science and medicine and various techniques developed in sciences and engineering can be utilized to attack the problem. We are developing new physical and radiobiological models for the formulation of inverse planning problem for various therapeutic modalities. We are also applying and improving a number of new signal processing and optimization algorithms to deal with this large scale and complex computerized decision-making task. Integration of biological imaging data into treatment planning is also being investigated.

4D Volumetric Modulated Arc Therapy (VMAT)