2019
Oh Y, Park Y, Cho JH, Wu H, Paulk NK, Liu LX, Kim N, Kay MA, Wu JC, Lin MZ. An orange calcium-modulated bioluminescent indicator for non-invasive activity imaging. Nature Chemical Biology 2019;15(5):433-436. PMID: 30936501. PMCID: 6563924
Seeger T, Shrestha R, Lam CK, Chen C, McKeithan WL, Lau E, Wnorowski A, McMullen G, Greenhaw M, Lee J, Oikonomopoulos A, Lee S, Yang H, Mercola M, Wheeler M, Ashley EA, Yang F, Karakikes I, Wu JC. A premature termination codon mutation in MYBPC3 causes hypertrophic cardiomyopathy via chronic activation of nonsense-mediated decay. Circulation 2019;139(6):799-811. PMID: 30586709. PMCID: 1512906
Tada Y, Heidary S, Tachibana A, Zaman J, Neofytou E, Dash R, Wu JC, Yang PC. Myocardial viability of the peri-infarct region measured by T1 mapping post manganese-enhanced MRI correlates with LV dysfunction. International Journal of Cardiology 2019;281:8-14. PMCID: 30739802. PMCID: 64334939
Zhang JZ, Termglinchan V, Shao NY, Itzhaki I, Liu C, Ma N, Tian L, Wang VY, Chang ACY, Guo H, Kitani T, Wu H, Lam CK, Kodo K, Sayed N, Blau HM, Wu JC. A human iPSC double-reporter system enables purification of cardiac lineage subpopulations with distinct function and drug response profiles. Cell Stem Cell 2019;24(5):802-811. PMID: 30880024. PMCID: 6499654
Kitani T, Ong SG, Lam CK, Rhee JW, Zhang JZ, Oikonomopoulos A, Ma N, Tian L, Lee J, Telli ML, Witteles RM, Sharma A, Sayed N, Wu JC. Human induced pluripotent stem cell model of trastuzumab-induced cardiac dysfunction in breast cancer patients. Circulation 2019;139(21):2451-2465. PMID: 30866650. PMCID: 6528817
Guo H, Tian L, Zhang JZ, Kitani T, Paik DT, Lee WH, Wu JC. Single-cell RNA sequencing of human embryonic stem cell differentiation delineates adverse effects of nicotine on embryonic development. Stem Cell Reports 2019;12(4):772-786. PMID: 30827876. PMCID: 6449785
Blinova K, Schocken D, Patel D, Daluwatte C, Vicente J, Wu JC, Strauss DG. Clinical trial in a dish: personalized stem cell derived cardiomyocyte assay compared to clinical trial results for two QT prolonging drugs. Clinical Translational Science 2019;12(6):687-697. PMID: 31328865. PMCID: 6853144
Zhang H, Tian L, Shen M, Tu C, Wu H, Gu M, Paik DT, Wu JC. Generation of quiescent cardiac fibroblasts from human induced pluripotent stem cells for in vitro modeling of cardiac fibrosis. Circulation Research 2019;125(5):552-566. PMID: 31288631. PMCID: 6768436
Goodyer WR, Beyersdorf BM, Paik DT, Tian L, Li G, Buikema JW, Chirikian O, Choi S, Venkatraman S, Adams EL, Tessier-Lavigne M, Wu JC, Wu SM. Transcriptomic profiling of the developing cardiac conduction system at single-cell resolution. Circulation Research 2019;125(4):379-397. PMID: 31284824. PMCID: 6675655
Kernik DC, Morotti S, Wu H, Garg P, Duff HJ, Kurokawa J, Jalife J, Wu JC, Grandi E, Clancy CE. A computational model of induced pluripotent stem-cell derived cardiomyocytes incorporating experimental variability from multiple data sources. Journal of Physiology 2019;597(17):4533-4564. PMID: 31278749. PMCID: 6767694
Sass G, Madigan RT, Joubert LM, Bozzi A, Sayed N, Wu JC, Stevens DA. A Combination of Itraconazole and Amiodarone Is Highly Effective against Trypanosoma cruzi infection of human stem cell-derived cardiomyocytes. American Journal of Tropical Medicine and Hygiene 2019;101(2):383-391. PMID: 31219005. PMCID: 6685576
Wu H, Yang H, Rhee JW, Zhang JZ, Lam CK, Sallam K, Chang ACY, Ma N, Lee J, Zhang H, Blau HM, Bers DM, Wu JC. Modelling diastolic dysfunction in induced pluripotent stem cell-derived cardiomyocytes from hypertrophic cardiomyopathy patients. European Heart Journal 2019; 40(45):3685-3695. PMID: 31219556.
Belbachir N, Portero V, Al Sayed ZR, Gourraud JB, Dilasser F, Jesel L, Guo H, Wu H, Gaborit N, Guilluy C, Girardeau A, Bonnaud S, Simonet F, Karakachoff M, Pattier S, Scott C, Burel S, Marionneau C, Chariau C, Gaignerie A, David L, Genin E, Deleuze JF, Dina C, Sauzeau V, Loirand G, Baró I, Schott JJ, Probst V, Wu JC, Redon R, Charpentier F, Le Scouarnec S. RRAD mutation causes electrical and cytoskeletal defects in cardiomyocytes derived from a familial case of Brugada syndrome. European Heart Journal 2019; 40(37):3081-3094. PMID: 31114854
Lee J, Termglinchan V, Diecke S, Itzhaki I, Lam CK, Garg P, Lau E, Greenhaw M, Seeger T, Wu H, Zhang JZ, Chen X, Gil IP, Ameen M, Sallam K, Rhee JW, Churko J, Chaudhary R, Yi SA, Nam KH, Chour T, Wang PJ, Snyder MP, Chang HY, Karakikes I, Wu JC. Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy. Nature 2019;572(7769):335-340. PMID: 31316208. PMCID: 6779479
266) Li G, Tian L, Goodyer W, Kort EJ, Buikema JW, Xu A, Wu JC, Jovinge S, Wu SM. Single cell expression analysis reveals anatomical and cell cycle-dependent transcriptional shifts during heart development. Development 2019;146(12). pii: dev173476. PMID: 31142541. PMCID: 6602356
Bozzi A, Sayed N, Matsa E, Sass G, Neofytou E, Clemons KV, Correa-Oliveira R, Stevens DA, Wu JC. Using human induced pluripotent stem cell-derived cardiomyocytes as a model to study Trypanosoma cruzi infection. Stem Cell Reports 2019;12(6):1232-1241. PMID: 31105048. PMCID: 6565757
Lee WH, Ong SG, Zhou Y, Tian L, Bae HR, Baker N, Whitlatch A, Mohammadi L, Guo H, Nadeau KC, Springer ML, Schick SF, Bhatnagar A, Wu JC. Modeling cardiovascular risks of E-cigarettes with human-induced pluripotent stem cell-derived endothelial cells. Journal American College Cardiology 2019;73(21):2722-2737. PMID: 31146818. PMCID: 6637948 (*Covered by Yahoo, CNN, Fox Business, The Sun, CBS New York, CBS Bay Area, San Francisco Chronicle, and other major news outlet) (Editor-in-Chief’s Top Picks From 2019)
Ebert A, Joshi AU, Andorf S, Dai Y, Sampathkumar S, Chen H, Li Y, Garg P, Toischer K, Hasenfuss G, Mochly-Rosen D, Wu JC. Proteasome-dependent regulation of distinct metabolic states during long-term culture of human iPSC-derived cardiomyocytes. Circulation Research 2019;125(1):90-103. PMID: 31104567. PMCID: 6613799
Lam CK, Tian L, Belbachir N, Wnorowski A, Shrestha R, Ma N, Kitani T, Rhee JW, Wu JC. Identifying the transcriptome signatures of calcium channel blockers in human induced pluripotent stem cell-derived cardiomyocytes. Circulation Research 2019;125(2):212-222. PMID: 31079550. PMCID: 6610656
Sass G, Tsamo AT, Chounda GAM, Nangmo PK, Sayed N, Bozzi A, Wu JC, Nkengfack AE, Stevens DA. Vismione B interferes with Trypanosoma cruzi infection of Vero cells and human stem cell-derived cardiomyocytes. American Journal of Tropical Medicine and Hygiene 2019; 101(6):1359-1368. PMID: 31571568. PMCID: 6896885
Lau E, Han Y, Williams DR, Thomas CT, Shrestha R, Wu JC, Lam MPY. Splice-junction-based mapping of alternative isoforms in the human proteome. Cell Reports 2019;29(11):3751-3576. PMID: 31825849. PMCID: 6961840
Rohani L, Machiraju P, Sabouny R, Meng G, Liu S, Zhao T, Iqbal F, Ravandi A, Wu JC, Khan A, Shutt T, Rancourt D, Greenway SC. Reversible mitochondrial fragmentation in iPSC-derived cardiomyocytes from children with DCMA, a mitochondrial cardiomyopathy. Canadian Journal of Cardiology 2019;S0828-282X(19):31286-3.
Wnorowski A, Sharma A, Chen H, Wu H, Shao NY, Sayed N, Liu C, Countryman S, Stodieck LS, Rubins KH, Wu SM, Lee PHU, Wu JC. Effects of spaceflight on human induced pluripotent stem cell-derived cardiomyocyte structure and function. Stem Cell Reports 2019;13(6):960-969. PMID: 31708475. PMCID: 6915842 (*Covered by CNN, BBC, Yahoo News, and other major news outlet. Featured on journal cover)
Wirka RC, Wagh D, Paik DT, Pjanic M, Nguyen T, Miller CL, Kundu R, Nagao M, Coller J, Koyano TK, Fong R, Woo YJ, Liu B, Montgomery SB, Wu JC, Zhu K, Chang R, Alamprese M, Tallquist MD, Kim JB, Quertermous T. Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis. Nature Medicine 2019;25(8):1280-1289. PMID: 31359001.
Lau E, Paik DT, Wu JC. Systems-wide approaches in induced pluripotent stem cell models. Annual Review Pathology 2019;14:395-419. PMID: 30379619. PMCID: 1012802
Stack JP, Moslehi J, Sayed N, Wu JC. Cancer therapy-induced cardiomyopathy: can human induced pluripotent stem cell modelling help prevent it? European Hear Journal 2019;40(22):1764-1770. PMID: 29377985. PMCID: 1012807
Berry JL, Zhu W, Tang YL, Krishnamurthy P, Ge Y, Cooke JP, Chen Y, Garry DJ, Yang HT, Rajasekaran NS, Koch WJ, Li S, Domae K, Qin G, Cheng K, Kamp TJ, Ye L, Hu S, Ogle BM, Rogers JM, Abel ED, Davis ME, Prabhu SD, Liao R, Pu WT, Wang Y, Ping P, Bursac N, Vunjak-Novakovic G, Wu JC, Bolli R, Menasché P, Zhang J. Convergences of life sciences and engineering in understanding and treating heart failure. Circulation Research 2019;124(1):161-169. PMID: 30605412. PMCID: 6350935
Sayed N, Ameen M, Wu JC. Personalized medicine in cardio-oncology: the role of induced pluripotent stem cell. Cardiovascular Research 2019;115(5):949-959. PMID: 30768178. PMCID: 6933506
Abi-Gerges N, McMahon C, Vargas H, Sager P, Chui R, Stevens D, Davila J, Schaub JR, Wu JC, Del Rio C, Mathes C, Miller PE, Burns-Naas LA, Ghetti A. The West coast regional safety pharmacology society meeting update: Filling translational gaps in safety assessment. Journal Pharmacological Toxicology Methods 2019;98:106582. PMID: 31077805
Wu JC, Woo YJ, Mayerle M, Harrington RA, Quertermous T. Stanford Cardiovascular Institute. Circulation Research 2019;124(10):1420-1424. PMID: 31070998.
Williams IM, Wu JC. Generation of endothelial cells from human pluripotent stem cells. Arteriosclerosis Thrombosis Vascular Biology 2019;39(7):1317-1329. PMID: 31242035. PMCID: 6597190
Ouyang X, Telli ML, Wu JC. Induced pluripotent stem cell-based cancer vaccines. Frontiers Immunology 2019;10:1510. PMID: 31338094. PMCID: 6628907.
Wang L, Pegram MD, Wu JC. Induced pluripotent stem cells as a novel cancer vaccine. Expert Opinion Biological Therapy 2019:1-7. PMID: 31364894.
Pang L, Sager P, Yang X, Shi H, Sannajust F, Brock M, Wu JC, Abi-Gerges N, Lyn-Cook B, Berridge BR, Stockbridge N. Workshop Report: FDA Workshop on improving cardiotoxicity assessment with human-relevant platforms. Circulation Research 2019;125(9):855-867. PMID: 31600125. PMCID: 6788760
Wu JC, Garg P, Yoshida Y, Yamanaka S, Gepstein L, Hulot JS, Knollmann BC, Schwartz PJ. Towards precision medicine with human iPSCs for cardiac channelopathies. Circulation Research 2019;125(6):653-658. PMID: 31465267.
Qin X, Han D, Wu JC. Molecular imaging of cardiac regenerative medicine. Current Opinion in Biomedical Engineering 2019, 9:66–73.
Hajipour MJ, Mehrani M, Abbasi SH, Amin A, Kassaian SE, Garbern JC, Caracciolo G, Zanganeh S, Chitsazan M, Aghaverdi H, Kamali Shahri SM, Ashkarran A, Raoufi M, Bauser-Heaton H, Zhang J, Muehlschlegel JD, Moore A, Lee RT, Wu JC, Serpooshan V, Mahmoudi M. Nanoscale technologies for prevention and treatment of heart failure: challenges and opportunities. Chemical Reviews 2019;119(21):11352-11390. PMID: 31490059
2018
Rhee S, Chung JI, King DA, D'amato G, Paik DT, Duan A, Chang A, Nagelberg D, Sharma B, Jeong Y, Diehn M, Wu JC, Morrison AJ, Red-Horse K. Endothelial deletion of Ino80 disrupts coronary angiogenesis and causes congenital heart disease. Nature Communication 2018;9(1):368. PMID: 29371594. PMCID: 5785521
Lee AS, Inayathullah M, Lijkwan MA, Zhao X, Sun W, Parekh MB, Kooreman N, Malkovskiy AV, Lau E, Qin X, Pothineni VR, Park S, Hong WX, Sanchez-Freire V, Zhang WY, Ebert AD, Chan CK, Nguyen PK, Rajadas J, Wu JC. A novel slow release collagen matrix cross-linked with pro-survival factor analogs promotes stem cell survival for treatment of ischemic cardiovascular disease. Nature Biomedical Engineering 2018;2:104-113. PMID: 29721363
Kooreman NG, Kim Y, de Almeida PE, Termglinchan V, Diecke S, Shao NY, Wei TT, Yu H, Dey D, Nelakanti R, Brouwer T, Paik DT, Barfi I, Han A, Quax PHA, Hamming JF, Levy R, Davis MM, Wu JC. iPSC-based cancer vaccination: an autologous stem cell vaccine against cancer. Cell Stem Cell 2018;22(4):501-513. PMID: 29456158 PMCID: 6134179
Lee J, Shao NY, Paik DT, Wu H, Guo H, Termglinchan V, Churko JM, Kim Y, Kitani T, Zhao MT, Zhang Y, Wilson KD, Karakikes I, Snyder MP, Wu JC. SETD7 drives cardiac lineage commitment through stage-specific transcriptional activation. Cell Stem Cell 2018;22(3):428-444. PMID: 29499155. PMCID: 5785460
Abilez OJ, Tzatzalos E, Yang H, Zhao MT, Jung G, Zöllner AM, Tiburcy M, Riegler J, Matsa E, Shukla P, Zhuge Y, Chour T, Chen VC, Burridge PW, Karakikes I, Kuhl E, Bernstein D, Couture LA, Gold JD, Zimmermann WH, Wu JC. Passive stretch induces structural and functional maturation of engineered heart muscle as predicted by computational modeling. Stem Cells 2018;36(2):265-277. PMID: 29086457. PMCID: 5785460
Moneghetti KJ, Giraldeau G, Wheeler MT, Kobayashi Y, Vrtovec B, Boulate D, Kuznetsova T, Schnittger I, Wu JC, Myers J, Ashley E, Haddad F. Incremental value of right heart metrics and exercise performance to well-validated risk scores in dilated cardiomyopathy. European Heart Journal Cardiovascular Imaging2018;19(8):916-025. PMID: 28977353.
Zhao X, Chen H, Xiao D, Yang H, Itzhaki I, Qin X, Chour T, Aguirre A, Lehmann K, Kim Y, Shukla P, Holmstrom A, Zhang JZ, Zhuge Y, Ndoye BC, Zhao M, Neofytou E, Zimmermann WH, Jain M, Wu JC. Comparison of non-human primate vs. human induced pluripotent stem cell-derived cardiomyocytes for treatment of myocardial infarction. Stem Cell Report 2018;10(2):422-435. PMID: 29398480. PMCID: 5830958
Qin X, Chen H, Yang H, Wu H, Zhao X, Wang H, Chour T, Neofytou E, Ding D, Daldrup-Link H, Heilshorn SC, Li K, Wu JC. Photoacoustic imaging of embryonic stem cell-derived cardiomyocytes in living hearts with ultrasensitive semiconducting polymer nanoparticles. Advanced Functional Materials 2018; 28(1): 1704939. PMID: 30473658
Argenziano M, Lambers E, Hong L, Sridhar A, Zhang M, Chalazan B, Menon A, Savio-Galimberti E, Wu JC, Rehman J, Darbar D. Electrophysiologic characterization of calcium handling in human induced pluripotent stem cell-derived atrial cardiomyocytes. Stem Cell Reports 2018;1867-1878. PMID: 29731429.
Millard D, Dang Q, Shi H, Zhang X, Strock C, Kraushaar U, Zeng H, Levesque P, Lu HR, Guillon JM,Wu JC, Li Y, Luerman G, Anson B, Guo L, Clements M, Abassi YA, Ross J, Pierson J, Gintant G. Cross-site reliability of human induced pluripotent stem-cell derived cardiomyocyte based safety assays using microelectrode arrays: results from a blinded CiPA pilot study. Toxicological Sciences 2018;8(1):6618. PMID: 29718449.
Sharma A, Zhang Y, Buikema JW, Serpooshan V, Chirikian O, Kosaric N, Churko JM, Dzilic E, Shieh A, Burridge PW, Wu JC, Wu SM. Stage-specific effects of bioactive lipids on human iPSC cardiac differentiation and cardiomyocyte proliferation. Scientific Report 2018;8(1):6618. PMID: 29700394.
Cheng H, Dharmadhikari AV, xx, Wu JC, Lupski JR, Arnesen T, Cooper GM, Chung WK, Gecz J, Stessman HAF, Meng L, Lyon GJ. Truncating variants in NAA15 are associated with variable levels of intellectual disability, autism spectrum disorder, and congenital anomalies. American Journal Human Genetics2018;102(5):985-994. PMID: 29656860.
Adam M, Kooreman N, Jagger A, Wagenhaeuser MU, Mehrkens D, Wang Y, Kayama Y, Toyama K, Raaz U, Schellinger IN, Maegdefessel L, Spin JM, Hamming JF, Quax PHA, Baldus S, Wu JC, Tsao PS.Systemic upregulation of IL-10 (Interleukin-10) using a nonimmunogenic vector reduces growth and rate of dissecting abdominal aortic aneurysm. Arterioscler Thromb Vasc Biol 2018; 38(8):1796-1805. PMID: 29880489.
Ma N, Zhang J, Itzhaki I, Zhang SL, Chen H, Haddad F, Kitani T, Wilson KD, Tian L, Shrestha R, Wu H, Lam CK, Sayed N, Wu JC. Determining the pathogenicity of a genomic variant of uncertain significance using CRISPR/Cas9 and human-induced pluripotent stem cells. Circulation 2018; Epub ahead of print. PMID: 29914921.
Vrtovec B, Poglajen G, Sever M, Zemljic G, Frljak S, Cerar A, Cukjati M, Jaklic M, Cernelc P, Haddad F,Wu JC. Effects of Repetitive Transendocardial CD34+ cell transplantation in patients with non-ischemic dilated cardiomyopathy. Circulation Research 2018;123(3):389-396. PMID: 9880546. PMCID: pending
Paik DT, Tian L, Lee J, Sayed N, Chen IY, Rhee S, Rhee JW, Kim Y, Wirka RC, Buikema JW, Wu SM, Red-Horse K, Quertermous T, Wu JC. Large-scale single-cell RNA-seq reveals molecular signatures of heterogeneous populations of human induced pluripotent stem cell-derived endothelial cells. Circulation Research2018;123:443-450. PMID: 29986945.
Chang ACY, Chang ACH, Kirillova A, Sasagawa K, Su W, Weber G, Lin J, Termglinchan V, Karakikes I, Seeger T, Dainis AM, Hinson JT, Seidman J, Seidman CE, Day JW, Ashley E, Wu JC, Blau HM. Telomere shortening is a hallmark of genetic cardiomyopathies. Proceedings National Academy of Science 2018;115(37):9276-9281. PMID: 30150400.
Liu Q, Van Bortle K, Zhang Y, Zhao MT, Zhang JZ, Geller BS, Gruber JJ, Jiang C, Wu JC, Snyder MP. Disruption of mesoderm formation during cardiac differentiation due to developmental exposure to 13-cis-retinoic acid. Scientific Report 2018;8(1):12960. PMID: 30154523.
Kim JB, Kobayashi Y, Kuznetsova T, Moneghetti KJ, Brenner DA, O'Malley R, Dao C, Wu JC, Fischbein M, Craig Miller D, Yeung AC, Liang D, Haddad F, Fearon WF. Cytokines profile of reverse cardiac remodeling following transcatheter aortic valve replacement. International Journal Cardiology 2018;270:83-88. PMID: 30219541.
Garg P, Oikonomopoulos A, Chen H, Li Y, Lam CK, Sallam K, Perez M, Lux RL, Sanguinetti MC, Wu JC. Genome editing of induced pluripotent stem cells to decipher cardiac channelopathy variant. Journal American College Cardiology 2018;72(1):62-75. PMID: 29957233
Lau E, Venkatraman V, Thomas CT, Wu JC, Van Eyk JE, Lam MPY. Identifying high-priority proteins across the human diseasome using semantic similarity. Journal Proteome Research 2018; Epub ahead of print. PMID: 3025117.
Churko JM, Garg P, Treutlein B, Venkatasubramanian M, Wu H, Lee J, Wessells QN, Chen SY, Chen WY, Chetal K, Mantalas G, Neff N, Jabart E, Sharma A, Nolan GP, Salomonis N, Wu JC. Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis. Nature Communication2018;9(1):4906. PMID: 30464173.
Cao Y, Chen H, Qiu R, Hanna M, Ma E, Hjort M, Zhang A, Lewis RS, Wu JC, Melosh NA. Universal intracellular biomolecule delivery with precise dosage control. Science Advance 2018;4(10):eaat8131. PMID: 30402539.
A Premature Termination Codon Mutation in MYBPC3 Causes Hypertrophic Cardiomyopathy via Chronic Activation of Nonsense-Mediated Decay. Seeger T, Shrestha R, Lam CK, Chen C, McKeithan WL, Lau E, Wnorowski A, McMullen G, Greenhaw M, Lee J, Oikonomopoulos A, Lee S, Yang H, Mercola M, Wheeler M, Ashley EA, Yang F, Karakikes I, Wu JC. Circulation 2018: Epub ahead of print. PMID: 30586709.
Iskandrian AE, Dilsizian V, Garcia EV, Beanlands RS, Cerqueira M, Soman P, Berman DS, Cuocolo A, Einstein AJ, Morgan CJ, Hage FG, Schelbert HR, Bax JJ, Wu JC, Shaw LJ, Sadeghi MM, Tamaki N, Kaufmann PA, Gropler R, Dorbala S, Van Decker W. Myocardial perfusion imaging: Lessons learned and work to be done-update. Journal Nuclear Cardiology 2018;25(1):39-52. PMID: 29110288.
Ong SG, Lee WH, Zhou Y, Wu JC. Mining exosomal microRNAs from human-induced pluripotent stem cells-derived cardiomyocytes for cardiac regeneration. Methods Molecular Biology 2018;1733:127-136. PMID: 29435928
Stack JP, Moslehi J, Sayed N, Wu JC. Cancer therapy-induced cardiomyopathy: can human induced pluripotent stem cell modelling help prevent it? European Hear Journal 2018; Epub ahead of print. PMID: 29377985.
Magdy T, Schuldt AJT, Wu JC, Bernstein D, Burridge PW. Human induced pluripotent stem cell (hiPSC)-derived cells to assess drug cardiotoxicity: opportunities and problems. Annual Review Pharmacology Toxicology 2018;58:83-103. PMID: 28992430
Zhang JZ, Guo H, Wu JC. Applications of genetically engineered human pluripotent stem cell reporters in cardiac stem cell biology. Current Opinion Biotechnology 2018;52:66-73. PMID: 29579626.
Liu C, Oikonomopoulos A, Sayed N, Wu JC. Modeling human diseases with induced pluripotent stem cells: from 2D to 3D and beyond. Development 2018;145(5). Pii:dev156166. PMID: 29519889.
Oikonomopoulos A, Kitani T, Wu JC. Pluripotent stem cell-derived cardiomyocytes as a platform for cell therapy applications: progress and hurdles for clinical translation. Molecular Therapy 2018; Epub ahead. PMID: 29699941.
Wnorowski A, Yang H, Wu JC. Progress, obstacles, and limitations in the use of stem cells in organ-on-a-chip models. Advance Drug Delivery Review 2018;S0169-409x. PMID: 29885330.
Garg P, Garg V, Shrestha R, Sanguinetti MC, Kamp TJ, Wu JC. Human induced pluripotent stem cell-derived cardiomyocytes as models for cardiac channelopathies: a primer for non-electrophysiologists.Circulation Research 2018;123(2):224-243. PMID: 29976690.
Lau E, Paik DT, Wu JC. Systems-wide approaches in induced pluripotent stem cell models. Annual Review Pathology 2018; Epub ahead of print. PMID: 30379619.
Huang NF, Serpooshan V, Morris VB, Sayed N, Pardon G, Abilez OJ, Nakayama KH, Pruitt BL, Wu SM, Yoon YS, Zhang J, Wu JC. Big bottlenecks in cardiovascular tissue engineering. Commun Biol 2018;1:199. PMID: 30480100.
Sharma A, McKeithan WL, Serrano R, Kitani T, Burridge PW, Del Álamo JC, Mercola M, Wu JC. Use of human induced pluripotent stem cell-derived cardiomyocytes to assess drug cardiotoxicity. Nature Protocol2018;13(12):3018-3041. PMID: 30413796.
Berry JL, Zhu W, Tang YL, Krishnamurthy P, Ge Y, Cooke JP, Chen Y, Garry DJ, Yang HT, Rajasekaran NS, Koch WJ, Li S, Domae K, Qin G, Cheng K, Kamp TJ, Ye L, Hu S, Ogle BM, Rogers JM, Abel ED, Davis ME, Prabhu SD, Liao R, Pu WT, Wang Y, Ping P, Bursac N, Vunjak-Novakovic G, Wu JC, Bolli R, Menasché P, Zhang J. Convergences of life sciences and engineering in understanding and treating heart failure.Circulation Research 2019;124(1):161-169. PMID: 30605412.
Fernández-Avilés F, Sanz-Ruiz R, Climent AM, Badimon L, Bolli R, Charron D, Fuster V, Janssens S, Kastrup J, Kim HS, Lüscher TF, Martin JF, Menasché P, Pinto FJ, Simari RD, Stone GW, Terzic A, Willerson JT, Wu JC; TACTICS Writing Group. Global overview of the Transnational Alliance for Regenerative Therapies in Cardiovascular Syndromes (TACTICS) recommendations: a comprehensive series of challenges and priorities of cardiovascular regenerative medicine. Circulation Research 2018;122(2):199-201. PMID: 29348246.
Rhee JW, Wu JC. Cardiac cell cycle activation as a strategy to improve iPSC-derived cardiomyocyte therapy. Circulation Research 2018;122(1):14-16. PMID: 29301838. PMCID: 5773069
Wu JC, Qin X, Neofytou E. Radiolabeled duramycin: promising translational imaging of myocardial apoptosis. JACC Cardiovascular Imaging 2018; Epub ahead of print. PMID: 29454760.
Nishiga M, Guo H, Wu JC. Induced pluripotent stem cells as a biopharmaceutical factory for extracellular vesicles. European Heart Journal 2018;39(20):1848-1850. PMID: 29547885.
Rhee JW, Wu JC. Dyslipidaemia: In vivo genome editing of ANGPTL3: a therapy for atherosclerosis?Nature Review Cardiology 2018;15(5):259-260. PMID: 29618844.
Lau E, Wu JC. Omics, big data, and precision medicine in cardiovascular sciences. Circulation Research2018;122(9):1165-1168. PMID: 29700063.
Lam CK, Wu JC. Disease modelling and drug discovery for hypertrophic cardiomyopathy using pluripotent stem cells: how far have we come? European Heart Journal 2018; 39(43):3893-3895. PMID: 30010924.
Tu C, Chao BS, Wu JC. Strategies for improving the maturity of human induced pluripotent stem cell-derived cardiomyocytes. Circulation Research 2018;123(5):512-514. PMID: 30355143.
Wu JC. From the BCVS chair. Circulation Research 2018;23(8):942-943. PMID: 30355039.
Comparison of Non-human Primate versus Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Treatment of Myocardial Infarction.
Zhao X, Chen H, Xiao D, Yang H, Itzhaki I, Qin X, Chour T, Aguirre A, Lehmann K, Kim Y, Shukla P, Holmström A, Zhang JZ, Zhuge Y, Ndoye BC, Zhao M, Neofytou E, Zimmermann WH, Jain M, Wu JC.
Stem Cell Reports. 2018 Jan 26. pii: S2213-6711(18)30028-6. doi: 10.1016/j.stemcr.2018.01.002. [Epub ahead of print]
Cancer therapy-induced cardiomyopathy: can human induced pluripotent stem cell modelling help prevent it?
Stack JP, Moslehi J, Sayed N, Wu JC.
Eur Heart J. 2018 Jan 25. doi: 10.1093/eurheartj/ehx811. [Epub ahead of print]
Endothelial deletion of Ino80 disrupts coronary angiogenesis and causes congenital heart disease.
Rhee S, Chung JI, King DA, D'amato G, Paik DT, Duan A, Chang A, Nagelberg D, Sharma B, Jeong Y, Diehn M, Wu JC, Morrison AJ, Red-Horse K.
Nat Commun. 2018 Jan 25;9(1):368. doi: 10.1038/s41467-017-02796-3.
Global Overview of the Transnational Alliance for Regenerative Therapies in Cardiovascular Syndromes (TACTICS) Recommendations: A Comprehensive Series of Challenges and Priorities of Cardiovascular Regenerative Medicine.
Fernández-Avilés F, Sanz-Ruiz R, Climent AM, Badimon L, Bolli R, Charron D, Fuster V, Janssens S, Kastrup J, Kim HS, Lüscher TF, Martin JF, Menasché P, Pinto FJ, Simari RD, Stone GW, Terzic A, Willerson JT, Wu JC; TACTICS Writing Group.
Circ Res. 2018 Jan 19;122(2):199-201. doi: 10.1161/CIRCRESAHA.117.312099. No abstract available.
Cardiac Cell Cycle Activation as a Strategy to Improve iPSC-Derived Cardiomyocyte Therapy.
Rhee JW, Wu JC.
Circ Res. 2018 Jan 5;122(1):14-16. doi: 10.1161/CIRCRESAHA.117.312287. No abstract available.
2017
Gu M, Shao NY, Sa S, Li D, Termglinchan V, Ameen M, Karakikes I, Sosa G, Grubert F, Lee J, Cao A, Taylor S, Ma Y, Zhao Z, Chappell J, Hamid R, Austin ED, Gold JD, Wu JC, Snyder MP, Rabinovitch M. Patient-specific iPSC-derived endothelial cells uncover pathways that protect against pulmonary hypertension in BMPR2 mutation carriers. Cell Stem Cell 2017;20(4):490-504.
Tiburcy M, Hudson JE, Balfanz P, Schlick SF, Meyer T, Chang Liao ML, Levent E, Raad F, Zeidler S, Wingender E, Riegler J, Wang M, Gold JD, Kehat I, Wettwer E, Ravens U, Dierickx P, van Laake L, Goumans MJ, Khadjeh S, Toischer K, Hasenfuss G, Couture LA, Unger A, Linke WA, Araki T, Neel B, Keller G, Gepstein L, Wu JC, Zimmermann WH. Defined engineered human myocardium with advanced maturation for applications in heart failure modelling and repair. Circulation 2017;135(19):1832-1847.
Kobayashi Y, Moneghetti KJ, Boralkar K, Amsallem M, Tuzovic M, Liang D, Yang PC, Narayan S, Kuznetsova T, Wu JC, Schnittger I, Haddad F. Challenging the complementarity of different metrics of left atrial function: insight from a cardiomyopathy-based study. European Heart Journal: Cardiovascular Imaging 2017;18(10):1153-1162.
Lin ZC, McGuire AF, Burridge PW, Matsa E, Lou HY, Wu JC. Cui B. Accurate nanoelectrode recordings of human pluripotent stem cell-derived cardiomyocytes for assaying drugs and modeling disease. Microsystems & Nanoengineering 2017;3:16080.
Sa S, Gu M, Chappell J, Shao NY, Ameen M, Elliott KA, Li D, Grubert F, Li CG, Taylor S, Cao A, Ma Y, Fong R, Nguyen L, Wu JC, Snyder MP, Rabinovitch M. iPSC Model of pulmonary arterial hypertension reveals novel gene expression and patient specificity. American Journal of Respiratory Care and Critical Care Medicine 2017;195(5):930-941.
Chao MP, Gentles AJ, Chatterjee S, Lan F, Reinisch A, Corces MR, Xavy S, Shen J, Haag D, Chanda S, Sinha R, Morganti RM, Nishimura T, Ameen M, Wu H, Wernig M, Wu JC, Majeti R. Human AML-iPSCs reacquire leukemic properties after differentiation and model clonal variation of disease. Cell Stem Cell 2017;20(3):329-344.
Karakikes I, Termglinchan V, Cepeda DA, Lee J, Diecke S, Hendel A, Itzhaki I, Ameen M, Shrestha R, Wu H, Ma N, Shao NY, Seeger T, Woo NA, Wilson KD, Matsa E, Porteus MH, Sebastiano V, Wu JC. A comprehensive TALEN-based knockout library for generating human induced pluripotent stem cell-based models for cardiovascular diseases. Circulation Research 2017;120(10):1561-1571.
Cao Y, Hjort M, Chen H, Birey F, Leal-Ortiz SA, Han CM, Santiago JG, Paşca SP, Wu JC, Melosh NA. Nondestructive nanostraw intracellular sampling for longitudinal cell monitoring. Proceedings National Academy of Science 2017;114(10):E1866-E1874.
Serpooshan V, Chen P, Wu H, Lee S, Sharma A, Hu DA, Venkatraman S, Ganesan AV, Usta OB, Yarmush M, Yang F, Wu JC, Demirci U, Wu SM. Bioacoustic-enabled patterning of human iPSC-derived cardiomyocytes into 3D cardiac tissue. Biomaterials 2017;131:47-57.
Sharma A, Burridge PW, McKeithan WL, Serrano R, Shukla P, Sayed N, Churko JM, Kitani T, Wu H, Holmström A, Matsa E, Zhang Y, Kumar A, Fan AC, del Álamo JC, Wu SM, Moslehi JJ, Mercola M, Wu JC. High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells. Science Translational Medicine 2017;9(377):eaaf2584.
Lee S, Serpooshan V, Tong X, Venkatraman S, Lee M, Lee J, Chirikian O, Wu JC, Wu SM, Yang F. Contractile force generation by 3D hiPSC-derived cardiac tissues is enhanced by rapid establishment of cellular interconnection in matrix with muscle-mimicking stiffness. Biomaterials 2017;131:111-120.
Chuang W, Sharma A, Shukla P, Li G, Mall M, Rajarajan K, Abilez OJ, Hamaguchi R, Wu JC, Wernig M, Wu SM. Partial reprogramming of pluripotent stem cell-derived cardiomyocytes into neurons. Scientific Report 2017;7:44840
Lee AS, Tang C, Hong WX, Park S, Bazalova-Carter M, Nelson G Sanchez-Freire V, Bakerman I, Zhang W, Neofytou E, Connolly AJ, Chan CK, Graves EE, Weissman IL, Nguyen PK, Wu JC. External beam radiation therapy for the treatment of human pluripotent stem cell-derived teratomas. Stem Cells 2017;35(8):1994-2000.
Liu Q, Jiang C, Xu J, Zhao M, Van Bortle K, Cheng X, Wang G, Chang HY, Wu JC, Snyder MP. Genome-wide temporal profiling of transcriptome and open-chromatin of early cardiomyocyte differentiation derived from hiPSCs and hESCs. Circulation Research 2017;121(4):376-391.
Li X, Kuznetsova T, Cauwenberghs N, Wheeler M, Maecker H, Wu JC, Haddad F, Dai H. Autoantibody profiling on a plasmonic nano-gold chip for the early detection of hypertensive heart disease. Proceedings National Academy of Science 2017;114(27):7089-7094.
Lee WH, Chen WY, Shao NY, Xiao D, Qin X, Baker N, Bae HR, Wei TT, Wang Y, Shukla P, Wu H, Kodo K, Ong SG, Wu JC. Comparison of non-coding RNAs in exosomes and functional efficacy of human embryonic stem cell- versus induced pluripotent stem cell-derived cardiomyocytes. Stem Cells 2017;35(10):2138-2149.
Wanjare M, Hou L, Nakayama KH, Kim JJ, Mezak NP, Abilez OJ, Tzatzalos E, Wu JC, Huang NF. Anisotropic microfibrous scaffolds enhance the organization and function of cardiomyocytes derived from induced pluripotent stem cells. Biomaterials Sciences 2017;5(8):1567-1578. PMID: 28715029.
Gowrishankar G, Hardy J, Wardak M, Namavari M, Reeves RE, Neofytou E, Srinivasan A, Wu JC, Contag CH, Gambhir SS. Specific imaging of bacterial infection using 6″-18F-Fluoromaltotriose: a second-generation PET tracer targeting the maltodextrin transporter in bacteria. Journal Nuclear Medicine 2017;58(10):1679-1684.
Chamberland S, Yang HH, Pan MM, Evans SW, Guan S, Chavarha M, Yang Y, Salesse C, Wu H, Wu JC, Clandinin TR, Toth K, Lin MZ, St-Pierre F. Fast two-photon imaging of subcellular voltage dynamics in neuronal tissue with genetically encoded indicators. eLife 2017;6.pii:e25690.
Kooreman NG, de Almeida PE, Stack JP, Nelakanti RV, Diecke S, Shao NY, Swijnenburg RJ, Sanchez-Freire V, Matsa E, Liu C, Connolly AJ, Hamming JF, Quax PHA, Brehm MA, Greiner DL, Shultz LD, Wu JC. Alloimmune responses of humanized mice to human pluripotent stem cell therapeutics. Cell Report 2017;20(8):1978-1990.
Moneghetti KJ, Giraldeau G, Wheeler MT, Kobayashi Y, Vrtovec B, Boulate D, Kuznetsova T, Schnittger I, Wu JC, Myers J, Ashley E, Haddad F. Incremental value of right heart metrics and exercise performance to well-validated risk scores in dilated cardiomyopathy. European Heart Journal Cardiovascular Imaging 2017;
Churko JM, Lee J, Ameen M, Gu M, Venkatasubramanian M, Diecke S, Sallam K, Im H, Wang G, Gold JD, Salomonis N, Snyder MP, Wu JC. Transcriptomic and epigenomic differences in human induced pluripotent stem cells generated from six reprogramming methods. Nature Biomedical Engineering 2017;1:826-837.
Abilez OJ, Tzatzalos E, Yang H, Zhao MT, Jung G, Zöllner AM, Tiburcy M, Riegler J, Matsa E, Shukla P, Zhuge Y, Chour T, Chen VC, Burridge PW, Karakikes I, Kuhl E, Bernstein D, Couture LA, Gold JD, Zimmermann WH, Wu JC. Passive stretch induces structural and functional maturation of engineered heart muscle as predicted by computational modeling. Stem Cells 2017
Zhao M, Shao NY, Hu S, Ma N, Srinivasan R, Jahanbani F, Lee J, Zhang SL, Snyder MP, Wu JC. Cell Type-specific chromatin signatures underline regulatory DNA elements in human induced pluripotent stem cells and somatic cells. Circulation Research 2017;121:1237-1250.
Kim JB, Kobayashi Y, Moneghetti KJ, Brenner DA, O’Malley R, Schnittger I, Wu JC, Murtagh G, Beshiri A, Fischbein M, Miller DC, Liang D, Yeung AC, Haddad F, Fearon WC. GDF-15 (growth differentiation factor 15) is associated with lack of ventricular recovery and mortality after transcatheter aortic valve replacement. Circulation: Cardiovascular Interventions 2017
Zhao MT, Chen H, Liu Q, Shao NY, Sayed N, Wo HT, Zhang JZ, Ong SG, Liu C, Kim Y, Yang H, Chour T, Ma H, Gutierrez NM, Karakikes I, Mitalipov S, Snyder MP, Wu JC. Molecular and functional resemblance of differentiated cells derived from isogenic human iPSCs and SCNT-derived ESCs. Proceedings National Academy of Science 2017;114(52):E11111-E11120.
Termglinchan V, Seeger T, Chen C, Wu JC, Karakikes I. Efficient genome editing in induced pluripotent stem cells with engineered nucleases in vitro. Methods Molecular Biology 2017;1521:55-68.
Shi Y, Inoue H, Wu JC, Yamanaka S. Induced pluripotent stem cell technology: a decade of progress. Nature Review Drug Discovery 2017;16(2):115-130.
Seeger T, Porteus M, Wu JC. Genome editing in cardiovascular biology. Circulation Research 2017;120(5):778-780.
Wnorowski A, Wu JC. 3-dimensionally printed, native-like scaffolds for myocardial tissue engineering. Circulation Research 2017;120(8):1224-1226.
Povsic TJ, Scott R, Mahaffey KW, Blaustein R, Edelberg JM, Lefkowitz MP, Solomon SD, Fox JC, Healy KE, Khakoo AY, Losordo DW, Malik FI, Monia BP, Montgomery RL, Riesmeyer J, Schwartz GG, Zelenkofske SL, Wu JC, Wasserman SM, Roe MT. Navigating the future of cardiovascular drug development-leveraging novel approaches to drive innovation and drug discovery: summary of findings from the Novel Cardiovascular Therapeutics Conference. Cardiovascular Drugs and Therapy 2017;31(4):445-458.
Fernández-Avilés F, Sanz-Ruiz R, Climent AM, Badimon L, Bolli R, Charron D, Fuster V, Janssens S, Kastrup J, Kim HS, Lüscher TF, Martin JF, Menasché P, Simari RD, Stone GW, Terzic A, Willerson JT, Wu JC; TACTICS (Transnational Alliance for Regenerative Therapies in Cardiovascular Syndromes) Writing Group. Global position paper on cardiovascular regenerative medicine: Scientific statement of the transnational alliance for regenerative therapies in cardiovascular syndromes (TACTICS) international group for the comprehensive cardiovascular application of regenerative medicinal products. European Heart Journal 2017;38(33):2532-2546.
Zhang J, Li H, Trounson A, Wu JC, Niol P. Combining hiPSCs and human genetics: major applications in drug development. Cell Stem Cell 2017;21(2):161-165.
Mahmoudi M, Yu M, Serpooshan V, Wu JC, Langer R, Lee RT, Karp JM, Farokhzad OC. Multiscale technologies for treatment of ischemic cardiomyopathy. Nature Nanotechnology 2017;12(9):845-855.
Magdy T, Schuldt AJT, Wu JC, Bernstein D, Burridge PW. Human induced pluripotent stem cell (hiPSC)-derived cells to assess drug cardiotoxicity: opportunities and problems. Annual Review Pharmacology Toxicology 2017
Iskandrian AE, Dilsizian V, Garcia EV, Beanlands RS, Cerqueira M, Soman P, Berman DS, Cuocolo A, Einstein AJ, Morgan CJ, Hage FG, Schelbert HR, Bax JJ, Wu JC, Shaw LJ, Sadeghi MM, Tamaki N, Kaufmann PA, Gropler R, Dorbala S, Van Decker W. Myocardial perfusion imaging: Lessons learned and work to be done-update. Journal Nuclear Cardiology 2017
2016
Riegler J, Ebert A, Qin X, Shen Q, Wang M, Ameen M, Kodo K, Ong SG, Lee WH, Lee G, Neofytou E, Gold JD, Connolly AJ, Wu JC. Comparison of magnetic resonance imaging and serum biomarkers for detection of human pluripotent stem cell-derived teratomas. Stem Cell Reports 2016;6(2):176-87.
Burridge PW, Li YF, Matsa E, Wu H, Ong SG, Sharma A, Holmstrom A, Chang AC, Coronado MJ, Ebert AD, Knowles JW, Telli ML, Witteles RM, Blau HM, Bernstein D, Altman RB, Wu JC. Human induced pluripotent stem-derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity. Nature Medicine 2016;22(5):547-56.
Jung G, Fajardo G, Ribeiro AJ, Kooiker KB, Coronado M, Zhao M, Hu DQ, Reddy S, Kodo K, Sriram K, Insel PA, Wu JC, Pruitt BL, Bernstein D. Time-dependent evolution of functional vs. remodeling signaling in induced pluripotent stem cell-derived cardiomyocytes and induced maturation with biomechanical stimulation. FASEB J 2016;30(4):1464-79.
Calderon D, Prot M, You S, Marquet C, Bellamy V, Bruneval P, Valette F, de Almeida P, Wu JC, Pucéat M, Menasché P, Chatenoud L. Control of immune response to allogeneic embryonic stem cells by CD3 antibody-mediated operational tolerance induction. American Journal Transplantation 2016;16(2):454-67.
He C, Hu H, Wilson KD, Wu H, Feng J, Xia S, Churko J, Qu K, Chang HY, Wu JC. Systematic characterization of long non-coding RNAs reveals the contrasting coordination of cis- and trans- molecular regulation in human fetal and adult heart. Circulation Cardiovascular Genetics 2016;9(2):110-118.
Yuan K, Shao NY, Hennigs JK, Discipulo M, Orcholski ME, Shamskhou E, Richter A, Hu X, Wu JC, de Jesus Perez V. Increased pyruvate dehydrogenase kinase 4 expression in lung pericytes is associated with reduced endothelial-pericyte interactions and small vessel loss in pulmonary arterial hypertension. American Journal Pathology 2016;186(9):2500-14.
Hu S, Zhao MT, Jahanbani F, Shao NY, Lee WH, Chen H, Snyder MP, Wu JC. Effects of cellular origin on differentiation of human induced pluripotent stem cell-derived endothelial cells. JCI Insight 2016;1(8). pii: e85558.
Mizutani M, Wu JC, Nusse R. Fibrosis of the neonatal mouse heart after cryoinjury is accompanied by Wnt signaling activation and epicardial-to-mesenchymal transition. Journal American Heart Association 2016;4(3):e002457.
Hnatiuk AP, Ong SG, Olea FD, Locatelli P, Riegler J, Lee WH, Jen CH, De Lorenzi A, Giménez CS, Laguens R, Wu JC, Crottogini A. Allogeneic mesenchymal stromal cells overexpressing mutant human hypoxia-inducible factor 1-α (HIF1-α) in an ovine model of acute myocardial infarction. Journal American Heart Association 2016;5(7):e003714.
Chang AC, Ong SG, LaGory EL, Kraft PE, Giaccia AJ, Wu JC, Blau HM. Telomere shortening and metabolic compromise underlie dystrophic cardiomyopathy. Proceedings National Academy of Science 2016;113(46):13120-13125.
Davis J, Davis LC, Correll RN, Makarewich CA, Schwanekamp JA, Moussavi-Harami F, Wang D, York AJ, Wu H, Houser SR, Seidman CE, Seidman JG, Regnier M, Metzger JM, Wu JC, Molkentin JD. A tension-based model distinguishes hypertrophic versus dilated cardiomyopathy. Cell 2016;165(5):1147-59.
Kuznetsova T, Haddad F, Tikhonoff V, Kloch-Badelek M, Ryabikov A, Knez J, Malyutina S, Stolarz-Skrzypek K, Thijs L, Schnittger I, Wu JC, Casiglia E, Narkiewicz K, Kawecka-Jaszcz K, Staessen JA; European Project On Genes in Hypertension (EPOGH) Investigators. Impact and pitfalls of scaling of left ventricular and atrial structure in population-based studies. Journal Hypertension 2016;34(6):1186-1194.
Vrtovec B, Sever M, Jensterle M, Poglajen G, Janez A, Kravos N, Zemljic G, Cukjati M, Cernelc P, Haddad F, Wu JC, Jorde UP. Efficacy of CD34+ stem cell therapy in nonischemic dilated cardiomyopathy is absent in patients with diabetes but preserved in patients with insulin resistance. Stem Cells Translational Medicine 2016;5(5):632-638.
Paik KJ, Maan ZN, Zielins ER, Duscher D, Whittam AJ, Morrison SD, Brett EA, Ransom RC, Hu MS, Wu JC, Gurtner GC, Longaker MT, Wan DC. Short Hairpin RNA silencing of PHD-2 improves neovascularization and functional outcomes in diabetic wounds and ischemic limbs. PLoS One 2016;11(3):e0150927.
Liang P, Sallam K*, Wu H, Li Y, Itzhaki I, Garg P, Zhang Y, Termglinchan V, Lan F, Gu M, Gong T, Zhuge Y, He C, Ebert AD, Sanchez-Freire V, Churko J, Hu S, Sharma A, Scheinman MM, Bers DM, Wu JC. Patient-specific and genome-edited induced pluripotent stem cell-derived cardiomyocytes elucidate single cell phenotype of Brugada Syndrome. Journal American College of Cardiology 2016;68(19):2086-2096.
Kodo K, Ong SG, Jahanbani F, Termglinchan V, Hirono K, InanlooRahatloo K, Ebert AD, Shukla P, Abilez OJ, Churko JM, Karakikes I, Jung G, Ichida F, Wu SM, Snyder MP, Bernstein D, Wu JC. iPSC-derived cardiomyocytes reveal abnormal TGF-β signalling in left ventricular non-compaction cardiomyopathy. Nature Cell Biology 2016;18(10):1031-42.
Shen-Orr SS, Furman D, Kidd BA, Haddad F, Lovelace P, Huang YW, Rosenberg-Hasson Y, Mackey S, Grisar FA, Pickman Y, Maecker HT, Chien YH, Dekker CL, Wu JC, Butte AJ, Davis MM. Defective signaling in the JAK-STAT pathway tracks with chronic inflammation and cardiovascular risk in aging humans. Cell Systems 2016;3(4):374-384.e4.
Qin X, Riegler J, Tiburcy M, Zhao X, Chour T, Ndoye B, Nguyen M, Adams J, Ameen M, Denney TS Jr, Yang PC, Nguyen P, Zimmermann WH, Wu JC. Magnetic resonance imaging of cardiac strain pattern following transplantation of human tissue engineered heart muscles. Circulation Cardiovascular Imaging 2016;9:e004731.
Matsa E, Burridge PW, Yu KH, Ahrens JH, Termglinchan V, Wu H, Liu C, Shukla P, Sayed N, Churko JM, Shao N, Woo NA, Chao AS, Gold JD, Karakikes I, Snyder MP, Wu JC. Transcriptome profiling of patient-specific human iPSC-cardiomyocytes predicts individual drug safety and efficacy responses in vitro. Cell Stem Cell 2016;19(3):311-325.
Golpanian S, Schulman IH, Ebert RF, Heldman AW, DiFede DL, Yang PC, Wu JC, Bolli R, Perin EC, Moyé L, Simari RD, Wolf A, Hare JM; Cardiovascular Cell Therapy Research Network. Concise review: review and perspective of cell dosage and routes of administration from preclinical and clinical studies of stem cell therapy for heart disease. Stem Cells Translational Medicine 2016;5(2):186-91.
Burridge PW, Diecke S, Matsa E, Sharma A, Wu H, Wu JC. Modeling cardiovascular diseases with patient-specific human pluripotent stem cell-derived cardiomyocytes. Methods Molecular Biology 2016;1353:119-30.
Tzatzalos E, Abilez OJ, Shukla P, Wu JC. Engineered heart tissues and induced pluripotent stem cells: Macro- and microstructures for disease modeling, drug screening, and translational studies. Advanced Drug Delivery Review 2016;96:234-44.
Sayed N, Liu C, Wu JC. Translation of human iPSCs: From clinical trial in a dish to precision medicine. Journal American College of Cardiology 2016;67(18):2161-76.
Lee WH, Nguyen PK, Fleischmann D, Wu JC. DNA damage-associated biomarkers in studying individual sensitivity to low-dose radiation from cardiovascular imaging. European Heart Journal 2016;37(40):3075-3080.
Chanana AM, Rhee JW, Wu JC. Human induced pluripotent stem cell approaches to model inborn and acquired metabolic heart diseases. Current Opinion Cardiology 2016;31(3):266-74.
Chen IY, Matsa E, Wu JC. Induced pluripotent stem cells: at the heart of cardiovascular precision medicine. Nature Review Cardiology 2016;13(6):333-49.
Gurvitz M, Burns KM, Brindis R, Broberg CS, Daniels CJ, Fuller SM, Honein MA, Khairy P, Kuehl KS, Landzberg MJ, Mahle WT, Mann DL, Marelli A, Newburger JW, Pearson GD, Starling RC, Tringali GR, Valente AM, Wu JC, Califf RM. Emerging research directions in adult congenital heart disease: a report from an NHLBI/ACHA working group. Journal American College Cardiology 2016;67(16):1956-64.
Ogle BM, Bursac N, Domian I, Huang NF, Menasché P, Murry CE, Pruitt B, Radisic M, Wu JC, Wu SM, Zhang J, Zimmermann WH, Vunjak-Novakovic G. Distilling complexity to advance cardiac tissue engineering. Science Translational Medicine 2016;8(342):342ps13.
Matsa E, Ahrens JH, Wu JC. Human induced pluripotent stem cells as a platform for personalized and precision cardiovascular medicine. Physiological Reviews 2016;96(3):1093-126.
Nguyen PK, Rhee JW, Wu JC. Adult stem cell therapy and heart failure, 2000 to 2016: a systematic review. JAMA Cardiology 2016;1(7):831-841.
Nguyen PK, Neofytou E, Rhee JW, Wu JC. Potential strategies for addressing the major clinical hurdles facing stem cell therapy. JAMA Cardiology 2016;1(8):953-962.
Sheng CC, Amiri-Kordestani L, Palmby T, Force T, Hong CC, Wu JC, Croce K, Kim G, Moslehi J. 21st century cardio-oncology : identifying cardiac safety signals in the era of personalized medicine. JACC: Basic to Translational Science 2016;1(5):386-398.
2015
Comparable calcium handling of human iPSC-derived cardiomyocytes generated by multiple laboratories.
Hwang HS, Kryshtal DO, Feaster TK, Sánchez-Freire V, Zhang J, Kamp TJ, Hong CC, Wu JC, Knollmann BC.
J Mol Cell Cardiol. 2015 Aug;85:79-88. doi: 10.1016/j.yjmcc.2015.05.003. Epub 2015 May 14.
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Haddad F, Spruijt OA, Denault AY, Mercier O, Brunner N, Furman D, Fadel E, Bogaard HJ, Schnittger I, Vrtovec B, Wu JC, de Jesus Perez V, Vonk-Noordegraaf A, Zamanian RT.
JACC Cardiovasc Imaging. 2015 Jun;8(6):627-38. doi: 10.1016/j.jcmg.2014.12.029. Epub 2015 May 14.
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A Rapid, High-Quality, Cost-Effective, Comprehensive, and Expandable Targeted Next-Generation Sequencing Assay for Inherited Heart Diseases.
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Dash R, Kim PJ, Matsuura Y, Ikeno F, Metzler S, Huang NF, Lyons JK, Nguyen PK, Ge X, Wong Po Foo C, McConnell MV, Wu JC, Yeung AC, Harnish P, Yang PC.
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Assessment of the Radiation Effects of Cardiac CT Angiography Using Protein and Genetic Biomarkers.
Nguyen PK, Lee WH, Li YF, Hong WX, Hu S, Chan C, Liang G, Nguyen I, Ong SG, Churko J, Wang J, Altman RB, Fleischmann D, Wu JC.
JACC Cardiovasc Imaging. 2015 Aug;8(8):873-84. doi: 10.1016/j.jcmg.2015.04.016. Epub 2015 Jul 22.
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Tumor promoting effects of myeloid derived suppressor cells are potentiated by hypoxia-induced expression of miR-210.
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Epigenetic Regulation of Phosphodiesterases 2A and 3A Underlies Compromised β-Adrenergic Signaling in an iPSC Model of Dilated Cardiomyopathy. Wu H, Lee J, Vincent LG, Wang Q, Gu M, Lan F, Churko JM, Sallam KI, Matsa E, Sharma A, Gold JD, Engler AJ, Xiang YK, Bers DM, Wu JC. Cell Stem Cell. 2015 Jun 16. pii: S1934-5909(15)00178-2.
Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Insights Into Molecular, Cellular, and Functional Phenotypes. Karakikes I, Ameen M, Termglinchan V, Wu JC. Circ Res. 2015 Jun 19;117(1):80-8.
Finding the rhythm of sudden cardiac death: new opportunities using induced pluripotent stem cell-derived cardiomyocytes. Sallam K, Li Y, Sager PT, Houser SR, Wu JC. Circ Res. 2015 Jun 5;116(12):1989-2004.
Schutt RC, Trachtenberg B, Cooke JP, Traverse JH, Henry TD, Pepine CJ, Willerson JT, Perin EC, Ellis SG, Zhao D, Bhatnagar A, Johnstone BH, Lai D, Resende M, Ebert RF, Wu JC, Sayre SL, Orozco A, Zierold C, Simari RD, Moyé L, Cogle CR, Taylor D. Bone marrow characteristics associated with changes in infarct size after STEMI: A biorepository evaluation from the CCTRN TIME Trial. Circulation Research 2015;116(1):99-107. PMID: 25406300
Nejadnik H, Diecke S, Lenkov OD, Chapelin F, Donig J, Tong X, Derugin N, Chan RC, Gaur A, Yang F, Wu JC, Daldrup-Link HE Improved Approach for Chondrogenic Differentiation of Human Induced Pluripotent Stem Cells. Stem Cell Reviews and Reports 2015; Epub ahead of print. PMID: 25578634
Serpooshan V, Sivanesan S, Huang X, Mahmoudi M, Malkovskiy AV, Zhao M, Inayathullah M, Wagh D, Zhang XJ, Metzler S, Bernstein D, Wu JC, Ruiz-Lozano P, Rajadas J. [Pyr1]-Apelin-13 delivery via nano-liposomal encapsulation attenuates pressure overload-induced cardiac dysfunction. Biomaterials 2015;37:289-98. PMID: 25443792
Pan Y, Leveson-Gower DB, de Almeida PE, Pierini A, Baker J, Florek M, Nishikii H, Kim BS, Ke R, Wu JC, Negrin RS. Engraftment of embryonic stem cells and differentiated progeny by host conditioning with total lymphoid irradiation and regulatory T cells. Cell Report 2015;S2211-1247(15)00208-9. PMID: 25801020.
Karakikes I, Stillitano F, Nonnenmacher M, Tzimas C, Sanoudou D, Termglinchan V, Kong CW, Rushing S, Hansen J, Ceholski D, Kolokathis F, Kremastinos D, Katoulis A, Ren L, Cohen N, Gho JM, Tsiapras D, Vink A, Wu JC, Asselbergs FW, Li RA, Hulot JS, Kranias EG, Hajjar RJ. Correction of human phospholamban R14del mutation associated with cardiomyopathy using targeted nucleases and combination therapy. Nature Communication 2015;6:6955. PMID: 25923014
Lara-Pezz E, Menasché P, Trouvin JH, Badimón L, Ioannidis JP, Wu JC, Hill JA, Koch WJ, De Felice AF, de Waele P, Steenwinckel V, Hajjar RJ, Zeiher AM. Guidelines for translational research in heart failure. Journal Cardiovascular Translational Research 2015;8(1):3-22. PMID: 25604959
Ong SG, Lee WH, Kodo K, Wu JC. MicroRNA-mediated regulation of differentiation and trans-differentiation in stem cells. Advanced Drug Delivery Reviews 2015; Epub. PMID: 25887992
Narula J, Chandrashekhar YS, Dilsizian V, Garcia MJ, Kramer CM, Malik S, Ryan T, Sen S, Wu JC. COCATS 4 Task Force 4: Training in Multimodality Imaging. Journal American College Cardiology2015;65(17):1788-85. PMID: 25777648
Wilson KD, Wu JC. Induced pluripotent stem cells. Journal American Medical Association 2015;313(16):1613-4. PMID: 25919522.
Modeling Cardiovascular Diseases with Patient-Specific Human Pluripotent Stem Cell-Derived Cardiomyocytes.
Burridge PW, Diecke S, Matsa E, Sharma A, Wu H, Wu JC.
Methods Mol Biol. 2015 Feb 18. [Epub ahead of print]
Enabling Consistency in Pluripotent Stem Cell-Derived Products for Research and Development and Clinical Applications Through Material Standards.
French A, Bravery C, Smith J, Chandra A, Archibald P, Gold JD, Artzi N, Kim HW, Barker RW, Meissner A, Wu JC, Knowles JC, Williams D, García-Cardeña G, Sipp D, Oh S, Loring JF, Rao MS, Reeve B, Wall I, Carr AJ, Bure K, Stacey G, Karp JM, Snyder EY, Brindley DA.
Stem Cells Transl Med. 2015 Feb 3. pii: sctm.2014-0233. [Epub ahead of print]
Teratoma formation: a tool for monitoring pluripotency in stem cell research.
Nelakanti RV, Kooreman NG, Wu JC.
Curr Protoc Stem Cell Biol. 2015 Feb 2;32:4A.8.1-4A.8.17. doi: 10.1002/9780470151808.sc04a08s32.
Multi-cellular interactions sustain long-term contractility of human pluripotent stem cell-derived cardiomyocytes.
Burridge PW, Metzler SA, Nakayama KH, Abilez OJ, Simmons CS, Bruce MA, Matsuura Y, Kim P,Wu JC, Butte M, Huang NF, Yang PC.
Am J Transl Res. 2014 Nov 22;6(6):724-35. eCollection 2014.
Novel codon-optimized mini-intronic plasmid for efficient, inexpensive, and xeno-free induction of pluripotency.
Diecke S, Lu J, Lee J, Termglinchan V, Kooreman NG, Burridge PW, Ebert AD, Churko JM, Sharma A, Kay MA, Wu JC.
Sci Rep. 2015 Jan 28;5:8081. doi: 10.1038/srep08081.
Variable activation of the DNA damage response pathways in patients undergoing single-photon emission computed tomography myocardial perfusion imaging.
Hee Lee W, Nguyen P, Hu S, Liang G, Ong SG, Han L, Sanchez-Freire V, Lee AS, Vasanawala M, Segall G, Wu JC.
Circ Cardiovasc Imaging. 2015 Feb;8(2). pii: e002851. doi: 10.1161/CIRCIMAGING.114.002851.
Improved Approach for Chondrogenic Differentiation of Human Induced Pluripotent Stem Cells.
Nejadnik H, Diecke S, Lenkov OD, Chapelin F, Donig J, Tong X, Derugin N, Chan RC, Gaur A, Yang F, Wu JC, Daldrup-Link HE.
Stem Cell Rev. 2015 Jan 13. [Epub ahead of print]
Intracoronary Transplantation of CD34(+) Cells Is Associated With Improved Myocardial Perfusion in Patients With Nonischemic Dilated Cardiomyopathy.
Lezaic L, Socan A, Poglajen G, Peitl PK, Sever M, Cukjati M, Cernelc P, Wu JC, Haddad F, Vrtovec B.
J Card Fail. 2015 Feb;21(2):145-52. doi: 10.1016/j.cardfail.2014.11.005. Epub 2014 Nov 18.
[Pyr1]-Apelin-13 delivery via nano-liposomal encapsulation attenuates pressure overload-induced cardiac dysfunction.
Serpooshan V, Sivanesan S, Huang X, Mahmoudi M, Malkovskiy AV, Zhao M, Inayathullah M, Wagh D, Zhang XJ, Metzler S, Bernstein D, Wu JC, Ruiz-Lozano P, Rajadas J.
Biomaterials. 2015 Jan;37:289-98. doi: 10.1016/j.biomaterials.2014.08.045. Epub 2014 Oct 13.
Bone Marrow Characteristics Associated With Changes in Infarct Size After STEMI: A Biorepository Evaluation From the CCTRN TIME Trial.
Schutt RC, Trachtenberg BH, Cooke JP, Traverse JH, Henry TD, Pepine CJ, Willerson JT, Perin EC, Ellis SG, Zhao DX, Bhatnagar A, Johnstone BH, Lai D, Resende M, Ebert RF, Wu JC, Sayre SL, Orozco A, Zierold C, Simari RD, Moyé L, Cogle CR, Taylor DA; Cardiovascular Cell Therapy Research Network (CCTRN).
Circ Res. 2015 Jan 2;116(1):99-107. doi: 10.1161/CIRCRESAHA.116.304710. Epub 2014 Nov 18.
2014
Human Stem Cells for Modeling Heart Disease and for Drug Discovery. |
Matsa E, Burridge PW, Wu JC. |
Sci Transl Med. 2014 Jun 4;6(239):239ps6. Review. |
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Transplanted terminally differentiated induced pluripotent stem cells are accepted by immune mechanisms similar to self-tolerance. |
de Almeida PE, Meyer EH, Kooreman NG, Diecke S, Dey D, Sanchez-Freire V, Hu S, Ebert A, Odegaard J, Mordwinkin NM, Brouwer TP, Lo D, Montoro DT, Longaker MT, Negrin RS, Wu JC. |
Nat Commun. 2014 May 30;5:3903. doi: 10.1038/ncomms4903. |
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Stem Cell Imaging: From Bench to Bedside. | |
Nguyen PK, Riegler J, Wu JC. | |
Cell Stem Cell. 2014 Apr 3;14(4):431-444. doi: 10.1016/j.stem.2014.03.009. Review. | |
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Modeling Inherited Cardiac Disorders. | |
Sallam K, Kodo K, Wu JC. | |
Circ J. 2014 Mar 17. [Epub ahead of print] | |
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Stem cells and cardiovascular drug development--reply. | |
Mordwinkin NM, Lee AS, Wu JC. | |
JAMA. 2014 Mar 12;311(10):1070-1. doi: 10.1001/jama.2014.634. No abstract available. | |
PMID: 24618976 [PubMed - in process] | |
Construction and validation of nano gold tripods for molecular imaging of living subjects. | |
Cheng K, Kothapalli SR, Liu H, Koh AL, Jokerst JV, Jiang H, Yang M, Li J, Levi J, Wu JC, Gambhir SS, Cheng Z. | |
J Am Chem Soc. 2014 Mar 5;136(9):3560-71. doi: 10.1021/ja412001e. Epub 2014 Feb 11. | |
PMID: 24495038 [PubMed - in process] | |
Human-induced pluripotent stem cell models of inherited cardiomyopathies. | |
Karakikes I, Termglinchan V, Wu JC. | |
Curr Opin Cardiol. 2014 Feb 26. [Epub ahead of print] | |
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Tracking gene and cell fate for therapeutic gain. | |
Kooreman NG, Ransohoff JD, Wu JC. | |
Nat Mater. 2014 Feb;13(2):106-9. doi: 10.1038/nmat3868. Review. No abstract available. | |
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Relationship between Echocardiographic and Magnetic Resonance Derived Measures of Right Ventricular Size and Function in Patients with Pulmonary Hypertension. | |
Shiran H, Zamanian RT, McConnell MV, Liang DH, Dash R, Heidary S, Sudini NL, Wu JC, Haddad F, Yang PC. | |
J Am Soc Echocardiogr. 2014 Jan 17. pii: S0894-7317(13)00969-3. doi: 10.1016/j.echo.2013.12.011. [Epub ahead of print] | |
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Predicting the future with stem cells. | |
Mohsin S, Wu JC, Sussman MA. | |
Circulation. 2014 Jan 14;129(2):136-8. doi: 10.1161/CIRCULATIONAHA.113.007045. Epub 2013 Nov 18. No abstract available. | |
PMID: 24249719 [PubMed - in process] Free PMC Article | |
Cardiac stem cell biology: glimpse of the past, present, and future. | |
Matsa E, Sallam K, Wu JC. | |
Circ Res. 2014 Jan 3;114(1):21-7. doi: 10.1161/CIRCRESAHA.113.302895. Review. | |
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Short hairpin RNA gene silencing of prolyl hydroxylase-2 with a minicircle vector improves neovascularization of hindlimb ischemia. | |
Lijkwan MA, Hellingman AA, Bos EJ, van der Bogt KE, Huang M, Kooreman NG, de Vries MR, Peters HA, Robbins RC, Hamming JF, Quax PH, Wu JC. | |
Hum Gene Ther. 2014 Jan;25(1):41-9. doi: 10.1089/hum.2013.110. Epub 2014 Jan 7. | |
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2013
Patient-specific stem cells and cardiovascular drug discovery. |
Mordwinkin NM, Lee AS, Wu JC. |
JAMA. 2013 Nov 20;310(19):2039-40. doi: 10.1001/jama.2013.282409. No abstract available. |
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Costimulation-adhesion blockade is superior to cyclosporine A and prednisone immunosuppressive therapy for preventing rejection of differentiated human embryonic stem cells following transplantation. |
Huber BC, Ransohoff JD, Ransohoff KJ, Riegler J, Ebert A, Kodo K, Gong Y, Sanchez-Freire V, Dey D, Kooreman NG, Diecke S, Zhang WY, Odegaard J, Hu S, Gold JD, Robbins RC, Wu JC. |
Stem Cells. 2013 Nov;31(11):2354-63. doi: 10.1002/stem.1501. |
PMID: 24038578 [PubMed - in process] |
CD34+ stem cell therapy in nonischemic dilated cardiomyopathy patients. |
Vrtovec B, Poglajen G, Sever M, Lezaic L, Socan A, Haddad F, Wu JC. |
Clin Pharmacol Ther. 2013 Oct;94(4):452-8. doi: 10.1038/clpt.2013.134. Epub 2013 Jul 31. Review. |
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Noninvasive imaging of hypoxia-inducible factor-1α gene therapy for myocardial ischemia. |
Chen IY, Gheysens O, Li Z, Rasooly JA, Wang Q, Paulmurugan R, Rosenberg J, Rodriguez-Porcel M, Willmann JK, Wang DS, Contag CH, Robbins RC, Wu JC, Gambhir SS. |
Hum Gene Ther Methods. 2013 Oct;24(5):279-88. doi: 10.1089/hgtb.2013.028. |
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Comparison of transendocardial and intracoronary CD34+ cell transplantation in patients with nonischemic dilated cardiomyopathy. |
Vrtovec B, Poglajen G, Lezaic L, Sever M, Socan A, Domanovic D, Cernelc P, Torre-Amione G, Haddad F, Wu JC. |
Circulation. 2013 Sep 10;128(11 Suppl 1):S42-9. doi: 10.1161/CIRCULATIONAHA.112.000230. |
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Screening drug-induced arrhythmia events using human induced pluripotent stem cell-derived cardiomyocytes and low-impedance microelectrode arrays. |
Navarrete EG, Liang P, Lan F, Sanchez-Freire V, Simmons C, Gong T, Sharma A, Burridge PW, Patlolla B, Lee AS, Wu H, Beygui RE, Wu SM, Robbins RC, Bers DM, Wu JC. |
Circulation. 2013 Sep 10;128(11 Suppl 1):S3-13. doi: 10.1161/CIRCULATIONAHA.112.000570. |
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Global epigenomic reconfiguration during mammalian brain development. |
Lister R, Mukamel EA, Nery JR, Urich M, Puddifoot CA, Johnson ND, Lucero J, Huang Y, Dwork AJ, Schultz MD, Yu M, Tonti-Filippini J, Heyn H, Hu S, Wu JC, Rao A, Esteller M, He C, Haghighi FG, Sejnowski TJ, Behrens MM, Ecker JR. |
Science. 2013 Aug 9;341(6146):1237905. doi: 10.1126/science.1237905. Epub 2013 Jul 4. |
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Development of poly(β-amino ester)-based biodegradable nanoparticles for nonviral delivery of minicircle DNA. |
Keeney M, Ong SG, Padilla A, Yao Z, Goodman S, Wu JC, Yang F. |
ACS Nano. 2013 Aug 27;7(8):7241-50. doi: 10.1021/nn402657d. Epub 2013 Jul 16. |
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Tumorigenicity as a clinical hurdle for pluripotent stem cell therapies. |
Lee AS, Tang C, Rao MS, Weissman IL, Wu JC. |
Nat Med. 2013 Aug;19(8):998-1004. doi: 10.1038/nm.3267. Epub 2013 Aug 6. Review. |
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Molecular imaging: the key to advancing cardiac stem cell therapy. |
Chen IY, Wu JC. |
Trends Cardiovasc Med. 2013 Aug;23(6):201-10. doi: 10.1016/j.tcm.2012.12.003. Epub 2013 Apr 3. Review. |
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Clonal precursor of bone, cartilage, and hematopoietic niche stromal cells. |
Chan CK, Lindau P, Jiang W, Chen JY, Zhang LF, Chen CC, Seita J, Sahoo D, Kim JB, Lee A, Park S, Nag D, Gong Y, Kulkarni S, Luppen CA, Theologis AA, Wan DC, DeBoer A, Seo EY, Vincent-Tompkins JD, Loh K, Walmsley GG, Kraft DL, Wu JC, Longaker MT, Weissman IL. |
Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):12643-8. doi: 10.1073/pnas.1310212110. Epub 2013 Jul 15. |
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The role of SIRT6 protein in aging and reprogramming of human induced pluripotent stem cells. |
Sharma A, Diecke S, Zhang WY, Lan F, He C, Mordwinkin NM, Chua KF, Wu JC. |
J Biol Chem. 2013 Jun 21;288(25):18439-47. doi: 10.1074/jbc.M112.405928. Epub 2013 May 7. |
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Overview of high throughput sequencing technologies to elucidate molecular pathways in cardiovascular diseases. |
Churko JM, Mantalas GL, Snyder MP, Wu JC. |
Circ Res. 2013 Jun 7;112(12):1613-23. doi: 10.1161/CIRCRESAHA.113.300939. Review. |
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Induced pluripotency of human prostatic epithelial cells. |
Zhao H, Sun N, Young SR, Nolley R, Santos J, Wu JC, Peehl DM. |
PLoS One. 2013 May 22;8(5):e64503. doi: 10.1371/journal.pone.0064503. Print 2013. |
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Dissecting the molecular relationship among various cardiogenic progenitor cells. |
Dey D, Han L, Bauer M, Sanada F, Oikonomopoulos A, Hosoda T, Unno K, De Almeida P, Leri A, Wu JC. |
Circ Res. 2013 Apr 26;112(9):1253-62. doi: 10.1161/CIRCRESAHA.112.300779. Epub 2013 Mar 5. |
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Drug screening using a library of human induced pluripotent stem cell-derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity. |
Liang P, Lan F, Lee AS, Gong T, Sanchez-Freire V, Wang Y, Diecke S, Sallam K, Knowles JW, Wang PJ, Nguyen PK, Bers DM, Robbins RC, Wu JC. |
Circulation. 2013 Apr 23;127(16):1677-91. doi: 10.1161/CIRCULATIONAHA.113.001883. Epub 2013 Mar 21. |
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Effective delivery of stem cells using an extracellular matrix patch results in increased cell survival and proliferation and reduced scarring in skin wound healing. |
Lam MT, Nauta A, Meyer NP, Wu JC, Longaker MT. |
Tissue Eng Part A. 2013 Mar;19(5-6):738-47. doi: 10.1089/ten.TEA.2012.0480. Epub 2012 Nov 16. |
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Sacrificial layer technique for axial force post assay of immature cardiomyocytes. |
Taylor RE, Kim K, Sun N, Park SJ, Sim JY, Fajardo G, Bernstein D, Wu JC, Pruitt BL. |
Biomed Microdevices. 2013 Feb;15(1):171-81. doi: 10.1007/s10544-012-9710-3. |
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Immunogenicity of pluripotent stem cells and their derivatives. |
de Almeida PE, Ransohoff JD, Nahid A, Wu JC. |
Circ Res. 2013 Feb 1;112(3):549-61. doi: 10.1161/CIRCRESAHA.111.249243. Review. |
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A review of human pluripotent stem cell-derived cardiomyocytes for high-throughput drug discovery, cardiotoxicity screening, and publication standards. |
Mordwinkin NM, Burridge PW, Wu JC. |
J Cardiovasc Transl Res. 2013 Feb;6(1):22-30. doi: 10.1007/s12265-012-9423-2. Epub 2012 Nov 15. Review. |
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MicroRNA-302 increases reprogramming efficiency via repression of NR2F2. |
Hu S, Wilson KD, Ghosh Z, Han L, Wang Y, Lan F, Ransohoff KJ, Burridge P, Wu JC. |
Stem Cells. 2013 Feb;31(2):259-68. doi: 10.1002/stem.1278. |
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Advances in nanotechnology for the management of coronary artery disease. |
Rhee JW, Wu JC. |
Trends Cardiovasc Med. 2013 Feb;23(2):39-45. doi: 10.1016/j.tcm.2012.08.009. Epub 2012 Dec 13. Review. |
PMID: 23245913 [PubMed - indexed for MEDLINE] Free PMC Article |
Effects of intracoronary CD34+ stem cell transplantation in nonischemic dilated cardiomyopathy patients: 5-year follow-up. |
Vrtovec B, Poglajen G, Lezaic L, Sever M, Domanovic D, Cernelc P, Socan A, Schrepfer S, Torre-Amione G, Haddad F, Wu JC. |
Circ Res. 2013 Jan 4;112(1):165-73. doi: 10.1161/CIRCRESAHA.112.276519. Epub 2012 Oct 12. |
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Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells. |
Lan F, Lee AS, Liang P, Sanchez-Freire V, Nguyen PK, Wang L, Han L, Yen M, Wang Y, Sun N, Abilez OJ, Hu S, Ebert AD, Navarrete EG, Simmons CS, Wheeler M, Pruitt B, Lewis R, Yamaguchi Y, Ashley EA, Bers DM, Robbins RC, Longaker MT, Wu JC. |
Cell Stem Cell. 2013 Jan 3;12(1):101-13. doi: 10.1016/j.stem.2012.10.010. |
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American Journal of Nuclear Medicine and Molecular Imaging: Editorial Board (2014) e-Century Publishing Corporation. |
Seto B, Jacobs PM, Mach RH, Bulte JW, Cai W, Alavi A, Divgi CR, Wu JC. |
Am J Nucl Med Mol Imaging. 2013 Dec 15;4(1):89-95. eCollection 2013. No abstract available. |
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Loss of CDKN2B promotes p53-dependent smooth muscle cell apoptosis and aneurysm formation. |
Leeper NJ, Raiesdana A, Kojima Y, Kundu RK, Cheng H, Maegdefessel L, Toh R, Ahn GO, Ali ZA, Anderson DR, Miller CL, Roberts SC, Spin JM, de Almeida PE, Wu JC, Xu B, Cheng K, Quertermous M, Kundu S, Kortekaas KE, Berzin E, Downing KP, Dalman RL, Tsao PS, Schadt EE, Owens GK, Quertermous T. |
Arterioscler Thromb Vasc Biol. 2013 Jan;33(1):e1-e10. doi: 10.1161/ATVBAHA.112.300399. Epub 2012 Nov 15. |
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Imaging neural stem cell graft-induced structural repair in stroke. |
Daadi MM, Hu S, Klausner J, Li Z, Sofilos M, Sun G, Wu JC, Steinberg GK. |
Cell Transplant. 2013;22(5):881-92. |
PMID: 23044338 [PubMed - indexed for MEDLINE] |
Generation of human iPSCs from human peripheral blood mononuclear cells using non-integrative Sendai virus in chemically defined conditions. |
Churko JM, Burridge PW, Wu JC. |
Methods Mol Biol. 2013;1036:81-8. doi: 10.1007/978-1-62703-511-8_7. |
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MicroRNA expression profiling of human-induced pluripotent and embryonic stem cells. |
Sharma A, Wu JC. |
Methods Mol Biol. 2013;936:247-56. Review. |
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A transgenic tri-modality reporter mouse. |
Yan X, Ray P, Paulmurugan R, Tong R, Gong Y, Sathirachinda A, Wu JC, Gambhir SS. |
PLoS One. 2013 Aug 9;8(8):e73580. doi: 10.1371/journal.pone.0073580. eCollection 2013. |
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Enhanced Aβ(1-40) production in endothelial cells stimulated with fibrillar Aβ(1-42). |
Rajadas J, Sun W, Li H, Inayathullah M, Cereghetti D, Tan A, de Mello Coelho V, Chrest FJ, Kusiak JW, Smith WW, Taub D, Wu JC, Rifkind JM. |
PLoS One. 2013;8(3):e58194. doi: 10.1371/journal.pone.0058194. Epub 2013 Mar 7. |
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Cardiovascular molecular imaging as a tool to study biology. |
Rodriguez-Porcel M, Wu JC. |
Theranostics. 2013 Dec 9;3(11):914-5. doi: 10.7150/thno.6333. eCollection 2013. No abstract available. |
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2012
Pluripotent stem cells: immune to the immune system? |
Pearl JI, Kean LS, Davis MM, Wu JC. |
Sci Transl Med. 2012 Dec 12;4(164):164ps25. doi: 10.1126/scitranslmed.3005090. Review. |
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In vivo directed differentiation of pluripotent stem cells for skeletal regeneration. |
Levi B, Hyun JS, Montoro DT, Lo DD, Chan CK, Hu S, Sun N, Lee M, Grova M, Connolly AJ, Wu JC, Gurtner GC, Weissman IL, Wan DC, Longaker MT. |
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Sci Transl Med. 2012 Apr 18;4(130):130ra47. doi: 10.1126/scitranslmed.3003552. |
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Cell Stem Cell. 2012 Jan 6;10(1):16-28. doi: 10.1016/j.stem.2011.12.013. |
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2011
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J Biol Chem. 2011 Sep 16;286(37):32697-704. doi: 10.1074/jbc.M111.235739. Epub 2011 Jun 30. |
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Circulation. 2011 Sep 13;124(11 Suppl):S46-54. doi: 10.1161/CIRCULATIONAHA.110.014019. |
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Novel microRNA prosurvival cocktail for improving engraftment and function of cardiac progenitor cell transplantation. |
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An antibody against SSEA-5 glycan on human pluripotent stem cells enables removal of teratoma-forming cells. |
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Nat Biotechnol. 2011 Aug 14;29(9):829-34. doi: 10.1038/nbt.1947. |
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Circ Cardiovasc Genet. 2010 Oct;3(5):426-35. doi: 10.1161/CIRCGENETICS.109.934281. Epub 2010 Aug 23. |
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J Heart Lung Transplant. 2009 Nov;28(11):1158-1165.e1. doi: 10.1016/j.healun.2009.06.018. Epub 2009 Sep 26. |
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Hepatocyte growth factor or vascular endothelial growth factor gene transfer maximizes mesenchymal stem cell-based myocardial salvage after acute myocardial infarction. |
Deuse T, Peter C, Fedak PW, Doyle T, Reichenspurner H, Zimmermann WH, Eschenhagen T, Stein W, Wu JC, Robbins RC, Schrepfer S. |
Circulation. 2009 Sep 15;120(11 Suppl):S247-54. doi: 10.1161/CIRCULATIONAHA.108.843680. |
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Novel minicircle vector for gene therapy in murine myocardial infarction. |
Huang M, Chen Z, Hu S, Jia F, Li Z, Hoyt G, Robbins RC, Kay MA, Wu JC. |
Circulation. 2009 Sep 15;120(11 Suppl):S230-7. doi: 10.1161/CIRCULATIONAHA.108.841155. |
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Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells. |
Sun N, Panetta NJ, Gupta DM, Wilson KD, Lee A, Jia F, Hu S, Cherry AM, Robbins RC, Longaker MT, Wu JC. |
Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15720-5. doi: 10.1073/pnas.0908450106. Epub 2009 Sep 8. |
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Effects of cell number on teratoma formation by human embryonic stem cells. |
Lee AS, Tang C, Cao F, Xie X, van der Bogt K, Hwang A, Connolly AJ, Robbins RC, Wu JC. |
Cell Cycle. 2009 Aug 15;8(16):2608-12. Epub 2009 Aug 24. |
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Molecular and magnetic resonance imaging of human embryonic stem cell-derived neural stem cell grafts in ischemic rat brain. |
Daadi MM, Li Z, Arac A, Grueter BA, Sofilos M, Malenka RC, Wu JC, Steinberg GK. |
Mol Ther. 2009 Jul;17(7):1282-91. doi: 10.1038/mt.2009.104. Epub 2009 May 12. |
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Imaging gene expression in human mesenchymal stem cells: from small to large animals. |
Willmann JK, Paulmurugan R, Rodriguez-Porcel M, Stein W, Brinton TJ, Connolly AJ, Nielsen CH, Lutz AM, Lyons J, Ikeno F, Suzuki Y, Rosenberg J, Chen IY, Wu JC, Yeung AC, Yock P, Robbins RC, Gambhir SS. |
Radiology. 2009 Jul;252(1):117-27. doi: 10.1148/radiol.2513081616. Epub 2009 Apr 14. |
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Trafficking mesenchymal stem cell engraftment and differentiation in tumor-bearing mice by bioluminescence imaging. |
Wang H, Cao F, De A, Cao Y, Contag C, Gambhir SS, Wu JC, Chen X. |
Stem Cells. 2009 Jul;27(7):1548-58. doi: 10.1002/stem.81. |
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MicroRNA profiling of human-induced pluripotent stem cells. |
Wilson KD, Venkatasubrahmanyam S, Jia F, Sun N, Butte AJ, Wu JC. |
Stem Cells Dev. 2009 Jun;18(5):749-58. doi: 10.1089/scd.2008.0247. |
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Comparison of optical bioluminescence reporter gene and superparamagnetic iron oxide MR contrast agent as cell markers for noninvasive imaging of cardiac cell transplantation. |
Chen IY, Greve JM, Gheysens O, Willmann JK, Rodriguez-Porcel M, Chu P, Sheikh AY, Faranesh AZ, Paulmurugan R, Yang PC, Wu JC, Gambhir SS. |
Mol Imaging Biol. 2009 May-Jun;11(3):178-87. doi: 10.1007/s11307-008-0182-z. Epub 2008 Nov 25. |
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Imaging survival and function of transplanted cardiac resident stem cells. |
Li Z, Lee A, Huang M, Chun H, Chung J, Chu P, Hoyt G, Yang P, Rosenberg J, Robbins RC, Wu JC. |
J Am Coll Cardiol. 2009 Apr 7;53(14):1229-40. doi: 10.1016/j.jacc.2008.12.036. |
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Comparison of transplantation of adipose tissue- and bone marrow-derived mesenchymal stem cells in the infarcted heart. |
van der Bogt KE, Schrepfer S, Yu J, Sheikh AY, Hoyt G, Govaert JA, Velotta JB, Contag CH, Robbins RC, Wu JC. |
Transplantation. 2009 Mar 15;87(5):642-52. doi: 10.1097/TP.0b013e31819609d9. |
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Imaging of STAT3 signaling pathway during mouse embryonic stem cell differentiation. |
Xie X, Chan KS, Cao F, Huang M, Li Z, Lee A, Weissman IL, Wu JC. |
Stem Cells Dev. 2009 Mar;18(2):205-14. doi: 10.1089/scd.2008.0152. |
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Transplantation of human embryonic stem cell-derived endothelial cells for vascular diseases. |
Li Z, Han Z, Wu JC. |
J Cell Biochem. 2009 Feb 1;106(2):194-9. doi: 10.1002/jcb.22003. Review. |
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Modeling conduction in host-graft interactions between stem cell grafts and cardiomyocytes. |
Chen MQ, Yu J, Whittington RH, Wu JC, Kovacs GT, Giovangrandi L. |
Conf Proc IEEE Eng Med Biol Soc. 2009;2009:6014-7. doi: 10.1109/IEMBS.2009.5334024. |
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Bioluminescence reporter gene imaging of human embryonic stem cell survival, proliferation, and fate. |
Wilson KD, Huang M, Wu JC. |
Methods Mol Biol. 2009;574:87-103. doi: 10.1007/978-1-60327-321-3_8. |
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Long term non-invasive imaging of embryonic stem cells using reporter genes. |
Sun N, Lee A, Wu JC. |
Nat Protoc. 2009;4(8):1192-201. doi: 10.1038/nprot.2009.100. Epub 2009 Jul 23. |
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2008
In vivo imaging of embryonic stem cells reveals patterns of survival and immune rejection following transplantation. |
Swijnenburg RJ, Schrepfer S, Cao F, Pearl JI, Xie X, Connolly AJ, Robbins RC, Wu JC. |
Stem Cells Dev. 2008 Dec;17(6):1023-9. doi: 10.1089/scd.2008.0091. |
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Multimodal evaluation of in vivo magnetic resonance imaging of myocardial restoration by mouse embryonic stem cells. |
Hendry SL 2nd, van der Bogt KE, Sheikh AY, Arai T, Dylla SJ, Drukker M, McConnell MV, Kutschka I, Hoyt G, Cao F, Weissman IL, Connolly AJ, Pelletier MP, Wu JC, Robbins RC, Yang PC. |
J Thorac Cardiovasc Surg. 2008 Oct;136(4):1028-1037.e1. doi: 10.1016/j.jtcvs.2007.12.053. Epub 2008 Jun 6. |
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Short hairpin RNA interference therapy for ischemic heart disease. |
Huang M, Chan DA, Jia F, Xie X, Li Z, Hoyt G, Robbins RC, Chen X, Giaccia AJ, Wu JC. |
Circulation. 2008 Sep 30;118(14 Suppl):S226-33. doi: 10.1161/CIRCULATIONAHA.107.760785. |
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Comparison of different adult stem cell types for treatment of myocardial ischemia. |
van der Bogt KE, Sheikh AY, Schrepfer S, Hoyt G, Cao F, Ransohoff KJ, Swijnenburg RJ, Pearl J, Lee A, Fischbein M, Contag CH, Robbins RC, Wu JC. |
Circulation. 2008 Sep 30;118(14 Suppl):S121-9. doi: 10.1161/CIRCULATIONAHA.107.759480. |
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Immunosuppressive therapy mitigates immunological rejection of human embryonic stem cell xenografts. |
Swijnenburg RJ, Schrepfer S, Govaert JA, Cao F, Ransohoff K, Sheikh AY, Haddad M, Connolly AJ, Davis MM, Robbins RC, Wu JC. |
Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12991-6. doi: 10.1073/pnas.0805802105. Epub 2008 Aug 26. |
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Noninvasive radionuclide imaging of cardiac gene therapy: progress and potential. |
Hiona A, Wu JC. |
Nat Clin Pract Cardiovasc Med. 2008 Aug;5 Suppl 2:S87-95. doi: 10.1038/ncpcardio1113. Review. |
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Intracellular and extracellular targets of molecular imaging in the myocardium. |
Chun HJ, Narula J, Hofstra L, Wu JC. |
Nat Clin Pract Cardiovasc Med. 2008 Aug;5 Suppl 2:S33-41. doi: 10.1038/ncpcardio1161. Review. |
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Transcriptome alteration in the diabetic heart by rosiglitazone: implications for cardiovascular mortality. |
Wilson KD, Li Z, Wagner R, Yue P, Tsao P, Nestorova G, Huang M, Hirschberg DL, Yock PG, Quertermous T, Wu JC. |
PLoS One. 2008 Jul 9;3(7):e2609. doi: 10.1371/journal.pone.0002609. |
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Seeing is believing: tracking cells to determine the effects of cell transplantation. |
Pearl J, Wu JC. |
Semin Thorac Cardiovasc Surg. 2008 Summer;20(2):102-9. doi: 10.1053/j.semtcvs.2008.04.002. Review. |
PMID: 18707641 [PubMed - indexed for MEDLINE] |
In vitro and in vivo bioluminescence reporter gene imaging of human embryonic stem cells. |
Wilson K, Yu J, Lee A, Wu JC. |
J Vis Exp. 2008 May 2;(14). pii: 740. doi: 10.3791/740. |
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Imaging of VEGF receptor in a rat myocardial infarction model using PET. |
Rodriguez-Porcel M, Cai W, Gheysens O, Willmann JK, Chen K, Wang H, Chen IY, He L, Wu JC, Li ZB, Mohamedali KA, Kim S, Rosenblum MG, Chen X, Gambhir SS. |
J Nucl Med. 2008 Apr;49(4):667-73. doi: 10.2967/jnumed.107.040576. |
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Comparison of reporter gene and iron particle labeling for tracking fate of human embryonic stem cells and differentiated endothelial cells in living subjects. |
Li Z, Suzuki Y, Huang M, Cao F, Xie X, Connolly AJ, Yang PC, Wu JC. |
Stem Cells. 2008 Apr;26(4):864-73. doi: 10.1634/stemcells.2007-0843. Epub 2008 Jan 24. |
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Cardiac differentiation of embryonic stem cells with point-source electrical stimulation. |
Chen MQ, Xie X, Hollis Whittington R, Kovacs GT, Wu JC, Giovangrandi L. |
Conf Proc IEEE Eng Med Biol Soc. 2008;2008:1729-32. doi: 10.1109/IEMBS.2008.4649510. |
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Transcriptional and functional profiling of human embryonic stem cell-derived cardiomyocytes. |
Cao F, Wagner RA, Wilson KD, Xie X, Fu JD, Drukker M, Lee A, Li RA, Gambhir SS, Weissman IL, Robbins RC, Wu JC. |
PLoS One. 2008;3(10):e3474. doi: 10.1371/journal.pone.0003474. Epub 2008 Oct 22. |
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2007
Comparison of imaging techniques for tracking cardiac stem cell therapy. |
Zhang SJ, Wu JC. |
J Nucl Med. 2007 Dec;48(12):1916-9. No abstract available. |
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Spatial and temporal kinetics of teratoma formation from murine embryonic stem cell transplantation. |
Cao F, van der Bogt KE, Sadrzadeh A, Xie X, Sheikh AY, Wang H, Connolly AJ, Robbins RC, Wu JC. |
Stem Cells Dev. 2007 Dec;16(6):883-91. |
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In vivo imaging and evaluation of different biomatrices for improvement of stem cell survival. |
Cao F, Sadrzadeh Rafie AH, Abilez OJ, Wang H, Blundo JT, Pruitt B, Zarins C, Wu JC. |
J Tissue Eng Regen Med. 2007 Nov-Dec;1(6):465-8. doi: 10.1002/term.55. |
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Quantum dot imaging for embryonic stem cells. |
Lin S, Xie X, Patel MR, Yang YH, Li Z, Cao F, Gheysens O, Zhang Y, Gambhir SS, Rao JH, Wu JC. |
BMC Biotechnol. 2007 Oct 9;7:67. |
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Molecular imaging of bone marrow mononuclear cell homing and engraftment in ischemic myocardium. |
Sheikh AY, Lin SA, Cao F, Cao Y, van der Bogt KE, Chu P, Chang CP, Contag CH, Robbins RC, Wu JC. |
Stem Cells. 2007 Oct;25(10):2677-84. Epub 2007 Jul 12. |
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Differentiation, survival, and function of embryonic stem cell derived endothelial cells for ischemic heart disease. |
Li Z, Wu JC, Sheikh AY, Kraft D, Cao F, Xie X, Patel M, Gambhir SS, Robbins RC, Cooke JP, Wu JC. |
Circulation. 2007 Sep 11;116(11 Suppl):I46-54. |
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Cardiovascular molecular imaging. |
Wu JC, Bengel FM, Gambhir SS. |
Radiology. 2007 Aug;244(2):337-55. Epub 2007 Jun 25. Review. |
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Positron emission tomography imaging of conditional gene activation in the heart. |
Chang GY, Cao F, Krishnan M, Huang M, Li Z, Xie X, Sheikh AY, Hoyt G, Robbins RC, Hsiai T, Schneider MD, Wu JC. |
J Mol Cell Cardiol. 2007 Jul;43(1):18-26. Epub 2007 Mar 24. |
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A novel platform device for rodent echocardiography. |
Kutschka I, Sheikh AY, Sista R, Hendry SL, Chun HJ, Hoyt G, Kutschka W, Pelletier MP, Quertermous T, Wu JC, Robbins RC. |
ILAR J. 2007 Jun 6;49:E1-7. |
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Integration of genomics, proteomics, and imaging for cardiac stem cell therapy. |
Chun HJ, Wilson KO, Huang M, Wu JC. |
Eur J Nucl Med Mol Imaging. 2007 Jun;34 Suppl 1:S20-6. Review. |
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An unusual cause of stroke from a left atrial mass. |
Wu JC, Fishbein MC, Child JS. |
J Am Soc Echocardiogr. 2007 May;20(5):537.e1-2. |
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Molecular imaging of embryonic stem cell misbehavior and suicide gene ablation. |
Cao F, Drukker M, Lin S, Sheikh AY, Xie X, Li Z, Connolly AJ, Weissman IL, Wu JC. |
Cloning Stem Cells. 2007 Spring;9(1):107-17. |
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Clinical hurdles for the transplantation of cardiomyocytes derived from human embryonic stem cells: role of molecular imaging. |
Swijnenburg RJ, van der Bogt KE, Sheikh AY, Cao F, Wu JC. |
Curr Opin Biotechnol. 2007 Feb;18(1):38-45. Epub 2006 Dec 29. Review. |
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Genetic modification of embryonic stem cells with VEGF enhances cell survival and improves cardiac function. |
Xie X, Cao F, Sheikh AY, Li Z, Connolly AJ, Pei X, Li RK, Robbins RC, Wu JC. |
Cloning Stem Cells. 2007 Winter;9(4):549-63. |
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2006
Molecular imaging of human embryonic stem cells: keeping an eye on differentiation, tumorigenicity and immunogenicity. |
van der Bogt KE, Swijnenburg RJ, Cao F, Wu JC. |
Cell Cycle. 2006 Dec;5(23):2748-52. Epub 2006 Dec 1. |
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Proteomic analysis of reporter genes for molecular imaging of transplanted embryonic stem cells. |
Wu JC, Cao F, Dutta S, Xie X, Kim E, Chungfat N, Gambhir S, Mathewson S, Connolly AJ, Brown M, Wang EW. |
Proteomics. 2006 Dec;6(23):6234-49. |
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Right coronary cameral fistula resulting from surgery of double chamber right ventricle. |
Leeper NJ, Gupta A, Murphy DJ, Wu JC. |
J Am Soc Echocardiogr. 2006 Sep;19(9):1191.e9-11. No abstract available. |
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Overview of stem cells and imaging modalities for cardiovascular diseases. |
Chang GY, Xie X, Wu JC. |
J Nucl Cardiol. 2006 Jul;13(4):554-69. Review. |
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Noninvasive evaluation of immunosuppressive drug efficacy on acute donor cell survival. |
Gheysens O, Lin S, Cao F, Wang D, Chen IY, Rodriguez-Porcel M, Min JJ, Gambhir SS, Wu JC. |
Mol Imaging Biol. 2006 May-Jun;8(3):163-70. |
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Transcriptional profiling of reporter genes used for molecular imaging of embryonic stem cell transplantation. |
Wu JC, Spin JM, Cao F, Lin S, Xie X, Gheysens O, Chen IY, Sheikh AY, Robbins RC, Tsalenko A, Gambhir SS, Quertermous T. |
Physiol Genomics. 2006 Mar 13;25(1):29-38. Epub 2006 Jan 3. |
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Molecular imaging of cardiac stem cell transplantation. |
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Curr Cardiol Rep. 2006 Mar;8(2):147-54. Review. |
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18F-labeled bombesin analogs for targeting GRP receptor-expressing prostate cancer. |
Zhang X, Cai W, Cao F, Schreibmann E, Wu Y, Wu JC, Xing L, Chen X. |
J Nucl Med. 2006 Mar;47(3):492-501. |
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In vivo visualization of embryonic stem cell survival, proliferation, and migration after cardiac delivery. |
Cao F, Lin S, Xie X, Ray P, Patel M, Zhang X, Drukker M, Dylla SJ, Connolly AJ, Chen X, Weissman IL, Gambhir SS, Wu JC. |
Circulation. 2006 Feb 21;113(7):1005-14. Epub 2006 Feb 13. |
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Effects of epigenetic modulation on reporter gene expression: implications for stem cell imaging. |
Krishnan M, Park JM, Cao F, Wang D, Paulmurugan R, Tseng JR, Gonzalgo ML, Gambhir SS, Wu JC. |
FASEB J. 2006 Jan;20(1):106-8. Epub 2005 Oct 24. |
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Imaging chemically modified adenovirus for targeting tumors expressing integrin alphavbeta3 in living mice with mutant herpes simplex virus type 1 thymidine kinase PET reporter gene. |
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Before 2006
Human gene therapy and imaging: cardiology. |
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Common congenital heart disorders in adults. |
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Curr Probl Cardiol. 2004 Nov;29(11):641-700. Review. No abstract available. Erratum in: Curr Probl Cardiol. 2005 Mar;30(3):4 p following 167. |
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Molecular imaging of the kinetics of vascular endothelial growth factor gene expression in ischemic myocardium. |
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Circulation. 2004 Aug 10;110(6):685-91. |
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Molecular imaging of cardiovascular gene products. |
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Micro-positron emission tomography imaging of cardiac gene expression in rats using bicistronic adenoviral vector-mediated gene delivery. |
Chen IY, Wu JC, Min JJ, Sundaresan G, Lewis X, Liang Q, Herschman HR, Gambhir SS. |
Circulation. 2004 Mar 23;109(11):1415-20. Epub 2004 Mar 8. |
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Molecular imaging of cardiac cell transplantation in living animals using optical bioluminescence and positron emission tomography. |
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Positron emission tomography imaging of cardiac reporter gene expression in living rats. |
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Circulation. 2002 Jul 9;106(2):180-3. |
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Optical imaging of cardiac reporter gene expression in living rats. |
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Circulation. 2002 Apr 9;105(14):1631-4. |
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Noninvasive optical imaging of firefly luciferase reporter gene expression in skeletal muscles of living mice. |
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Mol Ther. 2001 Oct;4(4):297-306. |
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