Stanford’s animal care program is a cost recovery program and per diems are assessed to support the University’s biomedical and animal research enterprise. A daily inventory of animals is maintained by VSC staff. Per diem charges for animal care begin on the day animal arrival. Per diem rates on animals born in the animal facility usually begin on the day animals are weaned. The per diem charge covers husbandry (housing feeding, sanitation), animal health care for non-research related illnesses, and disease surveillance. Per diems do not cover veterinary, diagnostic laboratory, and pathology services for medical problems resulting from experimental procedures, special diet, or special husbandry requests; those services are billable to the investigator. Per diem rates are calculated by the VSC, reviewed & approved by the University, published here on an annual basis.
Please contact Ms. Ruth Burns if you encounter an erroneous charge or need VSC to review your invoice.
Animal welfare is of paramount importance to this University and part of per diems covers animal care costs associated with non-experimentally driven animal illnesses and morbidities. However, veterinary and husbandry fees are typically assessed for a number of conditions, such as:
- Separating overcrowded cages (see Rodent Overcrowding Rates above)
- Mouse Intracage Aggression (repeated)
- Malocclusion (repeated)
- Extended veterinary care beyond what's routine and customary
- Veterinary care and intervention due to experimentally driven, morbid conditions such as
- Tumors exceeding your APLAC protocol endpoints
- Chronic implants exhibiting criteria treatment or early euthanasia
- Chronic or experimental disease states (including aging) reaching/exceeding treatment or protocol dictated euthanasia criteria
Cage side monitoring cards should be used to document your animal care activities. Refer to your APLAC protocol for APLAC Guidelines.
- No documentation of post-surgical monitoring - If your protocol agrees to APLAC's Guideline for Rodent Survival Surgery then you must document that you are checking the animal daily for complications until sutures or wound clips are removed.
- Abandoning an anesthetized animal - If your protocol agrees to APLAC's Guideline for Rodent Survival Surgery then you may not leave an animal unattended until it fully recovers consciousness. Recovering animals should be monitored every 15 minutes until they are mobile.
- Animal with a surgical complication - Scientists are expected to monitor post-surgical animals at a sufficient frequency (minimum once daily) to detect post surgical complications and to provide intervention as necessary. Fee will be assessed if VSC must notify you that your animal has a post-surgical complication and needs your immediate attention.
- Tumors, no monitoring or insufficient monitoring - If your protocol agrees to APLAC's Guideline for Maintenance of Tumors in Rodents then you must document that you are monitoring a minimum of three times per week until signs of morbidity have been identified or a tumor approaches maximum size, and then daily thereafter until rodent is euthanized.
- Tumors, too large - Every tumor project has as a specified maximum allowable size as specified in your APLAC protocol. A fee will be assessed if VSC must notify you that your animal is carrying a tumor exceeding your protocol's maximum limit.
- Tumors, no documentation for early termination - Every tumor protocol has a list of early termination criteria, such as ulceration. A fee will be assessed if VSC must notify you that your animal shows signs of early termination as specified in your APLAC protocol.
- Chronic implants, no documentation for early termination - Animals with implants should be monitored at a sufficient frequency for entire duration of study so that you may detect a complication soon after it occurs. A fee will be assessed if VSC must notify you that your animal shows signs of early termination as specified in your APLAC protocol.
- Disease models, no documentaiton for early termination - Every project has a list of early termination criteria, such as tumor ulceration or extreme weight loss. Animals modeling a disease must be monitored at a sufficient frequency for entire duration of the disease condition so that you may detect a complication soon after it occurs. A fee will be assessed if VSC must notify you that your animal shows signs of early termination as specified in your APLAC protocol.
- Tail biopsy - If your protocol agrees to APLAC's Tail Clipping Mice guideline then you must ensure hemostasis after the procedure. A fee will be assessed if VSC must manage a bloody cage.
- The Responsible Person (RP) listed on cage card will be provided 24-hour notice to cull for nonemergency cases
- VSC will cull and bill your account if sick rodent is still in colony after the 24-hour deadline
- Ensure the correct RP and emergency phone number is listed on cage card