Our Center is based on four scientific pillars:
- Deep mechanistic analysis of the adaptive immune responses of COVID-19 patients, spanning serological, B cell and T cell responses,
- Analysis of immune responses in the blood as well as mucosal sites,
- Comparing immune responses induced by infection to those induced by candidate vaccines, and
- Studying medically underserved, underrepresented and at-risk patient populations.
Within these parameters, we will attempt to determine the factors that result in effective and durable immunity to SARS-CoV-2 infection.