Volumetric spiral chemical shift imaging of hyperpolarized [2-13C]pyruvate in a rat C6 glioma model. Park JM, Josan S, Jang T, Merchant M, Watkins R, Hurd RE, Recht LD, Mayer D, Spielman DM. Magn Reson Med. 2015 May 6. doi: 10.1002/mrm.25766. [Epub ahead of print] PMID: 25946547

Hyperpolarized [1,4-(13)C]-diethylsuccinate: a potential DNP substrate for in vivo metabolic imaging. Billingsley KL, Josan S, Park JM, Tee SS, Spielman-Sun E, Hurd R, Mayer D,Spielman D. NMR Biomed. 2014 Mar;27(3):356-62. doi: 10.1002/nbm.3071. Epub 2014 Jan 13. PMID: 24421249

Measuring mitochondrial metabolism in rat brain in vivo using MR Spectroscopy of hyperpolarized [2-¹³C]pyruvate. Park JM, Josan S, Grafendorfer T, Yen YF, Hurd RE, Spielman DM, Mayer D. NMR Biomed. 2013 Oct;26(10):1197-203. doi: 10.1002/nbm.2935. Epub 2013 Apr 2. PMID: 23553852

Metabolic response of glioma to dichloroacetate measured in vivo by hyperpolarized (13)C magnetic resonance spectroscopic imaging. Park JM, Recht LD, Josan S, Merchant M, Jang T, Yen YF, Hurd RE, Spielman DM, Mayer D. Neuro Oncol. 2013 Apr;15(4):433-41. doi: 10.1093/neuonc/nos319. Epub 2013 Jan 17. PMID: 23328814

Quantification of glutamate and glutamine using constant-time point-resolved spectroscopy at 3 T. Gu M, Zahr NM, Spielman DM, Sullivan EV, Pfefferbaum A, Mayer D. NMR Biomed. 2013 Feb;26(2):164-72. doi: 10.1002/nbm.2831. Epub 2012 Jul 4. PMID: 22761057

In vivo measurement of aldehyde dehydrogenase-2 activity in rat liver ethanol model using dynamic MRSI of hyperpolarized [1-(13) C]pyruvate. Josan S, Xu T, Yen YF, Hurd R, Ferreira J, Chen CH, Mochly-Rosen D, Pfefferbaum A, Mayer D, Spielman D. NMR Biomed. 2013 Jun;26(6):607-12. doi: 10.1002/nbm.2897. Epub 2012 Dec 6. PMID: 23225495

In vivo MRSI of hyperpolarized [1-(13)C]pyruvate metabolism in rat hepatocellular carcinoma. Darpolor MM, Yen YF, Chua MS, Xing L, Clarke-Katzenberg RH, Shi W, Mayer D, Josan S, Hurd RE, Pfefferbaum A, Senadheera L, So S, Hofmann LV, Glazer GM, Spielman DM. NMR Biomed. 2011 Jun;24(5):506-13. doi: 10.1002/nbm.1616. Epub 2010 Dec 12. PMID: 21674652

Designing adiabatic radio frequency pulses using the Shinnar-Le Roux algorithm. Balchandani P, Pauly J, Spielman D. Magn Reson Med. 2010 Sep;64(3):843-51. doi: 10.1002/mrm.22473. PMID: 20806378

Metabolic imaging in the anesthetized rat brain using hyperpolarized [1-13C] pyruvate and [1-13C] ethyl pyruvate. Hurd RE, Yen YF, Mayer D, Chen A, Wilson D, Kohler S, Bok R, Vigneron D, Kurhanewicz J, Tropp J, Spielman D, Pfefferbaum A. Magn Reson Med. 2010 May;63(5):1137-43. doi: 10.1002/mrm.22364. PMID: 20432284

In vivo application of sub-second spiral chemical shift imaging (CSI) to hyperpolarized 13C metabolic imaging: comparison with phase-encoded CSI. Mayer D, Yen YF, Levin YS, Tropp J, Pfefferbaum A, Hurd RE, Spielman DM. J Magn Reson. 2010 Jun;204(2):340-5. doi: 10.1016/j.jmr.2010.03.005. Epub 2010 Mar 9. PMID: 20346717

Parallel spectroscopic imaging reconstruction with arbitrary trajectories using k-space sparse matrices. Gu M, Liu C, Spielman DM. Magn Reson Med. 2009 Feb;61(2):267-72. doi: 10.1002/mrm.21838. PMID: 19165883

Slice-selective tunable-flip adiabatic low peak-power excitation pulse. Balchandani P, Pauly J, Spielman D. Magn Reson Med. 2008 May;59(5):1072-8. doi: 10.1002/mrm.21540. PMID: 18429017

Fast CT-PRESS-based spiral chemical shift imaging at 3 Tesla. Mayer D, Kim DH, Adalsteinsson E, Spielman DM. Magn Reson Med. 2006 May;55(5):974-8. PMID: 16586451

Regularized higher-order in vivo shimming. Kim DH, Adalsteinsson E, Glover GH, Spielman DM. Magn Reson Med. 2002 Oct;48(4):715-22. PMID: 12353290

Volumetric spectroscopic imaging with spiral-based k-space trajectories. Adalsteinsson E, Irarrazabal P, Topp S, Meyer C, Macovski A, Spielman DM. Magn Reson Med. 1998 Jun;39(6):889-98. PMID: 9621912

Estimating NAA in cortical gray matter with applications for measuring changes due to aging. Lim KO, Spielman DM. Magn Reson Med. 1997 Mar;37(3):372-7. PMID: 9055227

Magnetic resonance fluoroscopy using spirals with variable sampling densities. Spielman DM, Pauly JM, Meyer CH. Magn Reson Med. 1995 Sep;34(3):388-94. PMID: 7500878

RSL locations

The Richard M. Lucas Center for Medical Imaging

1201 Welch Rd, Stanford CA 94305-5488

Stanford School of Medicine Technology & Innovation Park

3155 Porter Drive, Palo Alto, CA 94304