2023 Biomarkers can point to right diet for weight loss
January 11, 2023 - Featured in Futurity:
BIOMARKERS CAN POINT TO RIGHT DIET FOR WEIGHT LOSS
Published December 2022 - Cell Press Journal:
A new analysis of data from a yearlong weight-loss study identifies behaviors and biomarkers that contribute to short- and long-term weight loss.
“Weight loss is enigmatic and complicated, but we can predict from the outset with the microbiome and metabolic biomarkers who will lose the most weight and who will keep it off.” -Michael Snyder
Distinct factors associated with short-term and long-term weight loss induced by low-fat or low-carbohydrate diet intervention
Highlights
•Distinct variables are associated with short-term and long-term weight-loss success
•The primary drivers for short-term weight loss are diet adherence and diet quality
•Long-term weight loss is related to personal multi-omics markers at baseline
•Baseline factors (e.g., RQ) can suggest precision approaches to weight loss
Summary
To understand what determines the success of short- and long-term weight loss, we conduct a secondary analysis of dietary, metabolic, and molecular data collected from 609 participants before, during, and after a 1-year weight-loss intervention with either a healthy low-carbohydrate (HLC) or a healthy low-fat (HLF) diet.