Stanford Bio-X Frontiers in Interdisciplinary Biosciences Seminar, "Injection of Hyaluronic Acid Particle Hydrogels after Ischemic Stroke Dictates Phenotypic Changes in Astrocytes"
Oct 03, 2019 (Thu) | 4:00 PM -5:00 PM
James H. Clark Center, 318 Campus Drive, Seminar Room S360 : Stanford, CA
Refreshments to be served at 3:45 PM; seminar begins at 4:00 PM. Following stroke, dying cells contribute to the large influx of highly reactive astrocytes and pro-inflammatory microglia that release cytokines and lead to a cytotoxic environment that causes further brain damage and prevents endogenous repair. Dr. Segura's laboratory is interested designing therapies to treat stroke related disability, which are administered weeks to months after stroke. Their approach is to inject hydrogel biomaterial scaffolds into the stroke lesion that can remove the cytotoxic environment and allow pro-repair mechanisms to evolve. In this talk, Dr. Segura will focus on our efforts to design hyaluronic acid microporous annealed particle (HA-MAP) hydrogels to treat stroke related tissue loss.
Contact: Cici Huber | 6507257472 | email@example.com