December 11, 2023

Congratulations to Dr. Sean Wu for receiving a multi-PI R01 grant from the NIH/NHLBI together with Dr. James Martin at Baylor University to address the inhibitory role of cell-contact on adult and human iPSC-derived cardiomyocyte proliferation with the focus on their effects on Hippo/Yap and Wnt signaling crosstalk. Dr. Wu’s role will be to examine the effects of perturbing cell-contact and Hippo/Yap and Wnt signaling using human iPSC-CMs model.

October 15, 2023

Congratulations to Dr. Tahmina Samad, post-doctoral fellow in the Cardiovascular Institute, for receiving the CIRM/ISCBRM Physician Scientist Post-doctoral Fellowship Award that will be supporting her research work on metabolomic analysis of human iPSC-derived cardiomyocytes from hypoplastic left heart syndrome patients and blood biomarker for heart failure in single ventricle patients. This funding starts on July 1st, 2024.

September 26, 2023

Congratulations to Dr. Sean Wu on being a co-principal investigator of the Advanced Research Project Agency for Health (ARPA-H) team that recently received a five-year $26.9M cooperative agreement to 3D bioprint full-scale human-sized hearts from cardiac cells that are in vitro differentiated from human iPSCs. This HEART project (led by Dr. Mark Skylar-Scott in the Pediatrics Basic Science and Engineering Program and the Department of Bioengineering) brings together fifteen different labs at Stanford to work together to address challenges in designing, constructing, and functionally testing a beating human-sized heart.

August 14, 2023

Congratulations to former lab members Jan Willem Buikema and Dr. Wu on their review article describing the use of cardiomyocyte proliferation pathway regulation to generate large population of human iPSC-derived cardiomyocytes published in the journal Development.

July 15, 2023

Congratulations to lab member Tahmina Samad, post-doctoral fellow in the Cardiovascular Institute, for publishing an editorial article in Nature Cardiovascular Research on the various in silico, in vitro, and in vivo models used in understanding the pathogenic mechanisms of congenital heart diseases.

July 10, 2023

Congratulations to Dr. Ali Reza Rais Sadati, a post-doc fellow in Pediatric Cardiology, for receiving a 3rd year support for his research on immunogenicity of cell free nucleic acids in pediatric heart transplant rejection.

July 1, 2023

Congratulations to Dr. Wu for starting his appointment as Chair of the Scientific Committee and as a member of the Board of Director of the Sarnoff Cardiovascular Foundation.

June 1, 2023

Congratulations to lab member Paul Heinrich, MD-PhD student, for publishing a commentary article in the Journal of Cardiovascular Aging on the mechanism of cardiomyocyte proliferation and maturation regulated by LRRC10 from a recently published paper in Science.

May 1, 2023

Congratulations to lab member Han Zhu, on her new appointment as an Assistant Professor of Medicine (Cardiovascular Medicine) at Stanford University School of Medicine/Stanford Health Care and as the Director of the Translational Cardio-Oncology Research in the Division of Cardiovascular Medicine. Her new research lab will be housed on the 3rd floor of the Biomedical Innovation (BMI) building.

March 15, 2023

Congratulations to MD-PhD student Francisco Galdos for his new paper describing the left ventricular cardiomyocyte predominant differentiation of human iPSCs using the standard Wnt on/off protocol as revealed by TBX5-Cre/LoxP-TurboGFP and MYL2-tdTomato double fluorescent reporter line published in eLife.

February 10, 2023

Congratulations to Dr. Wu for organizing a highly successful Keystone Symposium on Cardiac Development and Disease: From Genes to Cures at Eldorado Hotel in Santa Fe, NM together with Drs. Christine Seidman (Brigham & Women’s Hospital, Harvard Medical School) and Wolfram Zimmerman (University of Gottengen). Over 200 attendees participated in-person and online discussing mechanisms of heart development, genetics of cardiomyopathy, and regenerative therapy using stem cells. Current (Ali Reza Rais Sadati, Tahima Samad, Francisco Galdos, Paul Hein, Will Goodyer, Carissa Lee) and former (Soah Lee, Jan Buikema) members of Wu lab presented talks and posters at the meeting as well.

January 25, 2023

Congratulations to Dr. Sean Wu for his election to the Association of University Cardiologists, an organization that represents the 120 most recognized cardiologists in the U.S. including many of whom are chiefs or chairs of cardiology division/department in the country.

January 19, 2023

Congratulations to lab member Han Zhu, an Instructor in Cardiovascular Medicine, on publishing a review commentary in the journal Med on a recently published paper from Axelrod et al in Nature describing the role of troponin I peptide as an autoimmune trigger of myocarditis.

January 1, 2023

Congratulations to lab member Will Goodyer, on his new appointment as an Assistant Professor of Pediatric (Cardiology) at Stanford and Lucile Packard Children’s Hospital (LPCH). His new research lab will be housed in the CCSR building.

March 15, 2023

Congratulations to MD-PhD student Francisco Galdos for his new paper describing the left ventricular cardiomyocyte predominant differentiation of human iPSCs using the standard Wnt on/off protocol as revealed by TBX5-Cre/LoxP-TurboGFP and MYL2-tdTomato double fluorescent reporter line published in eLife.