Experimental Psychiatric Tests
The Elevated Plus Maze (EPM) test is used to assess anxiety-related behavior in rodent models of CNS disorders. The EPM apparatus consists of a "+"-shaped maze elevated above the floor with two oppositely positioned closed arms, two oppositely positioned open arms, and a center area. As subjects freely explore the maze, their behavior is recorded by means of a video camera mounted above the maze and analyzed using a video tracking system.
Prepulse inhibition (PPI), also termed as startle reduction or reflex modification, is a phenomenon in which a weak stimulus (Prepulse) can suppress the startle response to a subsequent stronger startle stimulus (pulse).