As part of the Wu Tsai Neurosciences Institute, BFNL provides a preclinical discovery platform for CNS target validation in preclinical in vivo and in vitro models. Our well validated neurobehavioral assessment tools in CNS disease models provide a unique platform for the screening and profiling of experimental therapeutics and genetic rodent models. We aim to accelerate the progress in both fundamental and applied studies of nervous system function. We collaborate with academic laboratories, non-profit foundations, and biopharmaceutical companies worldwide to support the understanding of human CNS disorders and develop therapeutic interventions.
Our overarching goal is to lead and enable translation of scientific discoveries into novel therapeutic approaches that improve the quality of life for patients with disorders of the brain and spinal cord. Our disease models focus includes: cognition and memory, pain, stroke, spinal cord injury, Alzheimer’s disease, Down syndrome, Huntington’s disease, ALS, Autism Spectrum Disorder, and Schizophrenia, as well as social interaction.
Stanford behavioral and functional neuroscience laboratory (SBFNL) is a state-of-the art facility designed to serve as a time-efficient and cost-effective service center for researchers in need of behavioral and neuropharmacological analyses in rodents. We will provide expertise in all aspects related to the design and implementation of behavioral experiments as well as data analysis and interpretation. The core is fully equipped to accommodate a full battery of behavioral tests relevant to learning and memory, sensory gating, place/ fear conditioning, motor function, nociception, and anxiety-related behaviors. We are specialized in genetic and pharmacological phenotyping in both mouse and rat. In addition the center provides expertise in an array of acute and chronic experimental models of neurodegenerative disorders such as stroke and ischemic brain injury.