DoD Peer Reviewed Medical Research Program

Amount of funding:  Total Costs will not exceed $3.5M. 
Purpose:  The PRMRP TTDA is a product-driven award mechanism intended to provide support for the translation of promising preclinical findings into products for clinical applications, including prevention, detection, diagnosis, treatment, or quality of life, for a disease or condition related to one of the FY25 PRMRP topic areas and one of the FY25 PRMRP strategic goals. The proposed experiments may be hypothesis or milestone driven. Products in development should be responsive to the health care needs of military Service Members, Veterans, and their Families. The product(s) to be developed under the FY25 PRMRP TTDA mechanism may be a tangible item, such as a pharmacologic agent (drugs or biologics) or device, or a knowledgebased product. (A “knowledge product” is a non-materiel product that addresses an identified need in a topic area, is based on current evidence and research, aims to transition into medical practice, training, tools, or to support materiel solutions [systems to develop, acquire, provide, and sustain medical solutions and capabilities], and educates or impacts behavior throughout the continuum of care, including primary prevention of negative outcomes.).
Eligibility: Independent investigators - Faculty with PI eligibility and CE faculty (with an approved CE faculty PI waiver obtained through their RPM in RMG prior to the pre-application/letter of intent) may be the PI. 
Not eligible: Instructors, Clinical Instructors, Postdoctoral Fellows, Clinical Fellows, Academic staff-researchers (i.e., research associates) are not eligible because Stanford does not consider them to hold independent or faculty-level positions.
Timeline:
Pre-Application (Letter of Intent) Submission Deadline: June 9, 2025 via eBrap
Please include your RPM’s name as business official in the pre-application.
Institutional representative (RPM/RMG or CGO/OSR) Deadline: July 14, 2025
Application submission Deadline: July 21, 2025 via grants.gov
Guidelines: https://cdmrp.health.mil/funding/prmrp

Amount of funding: Total Costs budgeted for the entire period of performance will not exceed $8M.
Purpose:  The PRMRP CTA supports the rapid execution and analysis of clinical trials with the potential to have a significant impact on the treatment or management of a disease or condition addressed in one of the congressionally directed FY25 PRMRP topic areas and FY25 PRMRP strategic goals. Clinical trials may be designed to evaluate promising new products, pharmacologic agents (drugs, biologics, or medical devices), clinical guidance, non-pharmacological interventions, and/or emerging approaches and technologies. Proposed projects may range from small proof-of-concept trials (i.e., pilot, first-in-human, phase 0) to demonstrate the feasibility or inform the design of more advanced trials through large-scale trials, including comparative effectiveness trials that will transform and revolutionize care for the diseases and conditions addressed in the FY25 PRMRP Topic Areas. 
PI Eligibility: Independent investigators - Faculty with PI eligibility and CE faculty (with an approved CE faculty PI waiver obtained through their RPM in RMG prior to the pre-application/letter of intent) may be the PI or Partnering PI.
Not eligible: Instructors, Clinical Instructors, Academic staff-research (i.e., research associates), and Postdocs are not eligible for this RFP because Stanford does not consider them to hold independent positions.
Timeline:
Pre-Application (Letter of Intent) Submission Deadline: June 9, 2025 via eBrap
Please include your RPM’s name as business official in the pre-application.
Institutional representative (RPM/RMG or CGO/OSR) Deadline: July 14, 2025
Application submission Deadline: July 21, 2025 via grants.gov
Guidelines: https://cdmrp.health.mil/funding/prmrp

Please include your institutional official's name (RPM/RMG or CGO/OSR) as business official in the pre-application/LOI.

eBRAP Funding Opportunities and Forms (including the General Application Instructions).