Our lab focusses on molecular mechanisms of disease that involve:
- differential subcellular compartmentalization
- differential protein shuttling
- differential protein complex formation and stoichiometries
All of which may constitute relevant pathomechanisms of disease beyond alterations in protein expression and may be critical for cell motility in general and cancer cell invasion and metastasis in particular.
Our tools, quantitative fluorescence microscopy and spectroscopy, are especially well suited to address questions related to these molecular mechanisms.