Heart disease is the leading cause of death in the United States and worldwide, but many people do not know they are at high risk. Doctors can look for early signs of heart disease by checking for calcium buildup in the heart’s arteries. A special type of scan, called a gated CT scan or coronary artery calcium scan, can detect this buildup and help doctors decide if a patient needs medicine to prevent a heart attack or stroke. But these scans are not commonly done, and insurance often does not cover them. However, millions of people get other kinds of chest CT scans for other health reasons. These scans can also show calcium in the heart, but this finding is often not reported or acted upon, and so patients frequently do not know about their risk. We are working to change this, and provide preventive treatment based upon this unused but important information.
We have created an artificial intelligence tool that can find this calcium on CT scans that were performed for other health reasons. This tool has been cleared by the FDA, and we want to use it to help more people get appropriate preventive cardiology care. The first goal of this study is to test the algorithm in a new patient population, specifically patients getting screened for lung cancer. These patients are at high risk for heart disease because of their smoking history. The second goal of our study is to understand the ethical and legal implications of a clinical program to screen for and treat patients identified as high risk by our AI tool. The final goal is to build a clinical program to provide high risk patients identified by AI with appropriate preventive cardiology care.
Over 1000 health AI algorithms are FDA-approved or -cleared. However, only a handful have successfully been deployed clinically to help patients. The goal of this project is to responsibly translate novel AI tools and research into sustainable, real-world patient impact through an AI-augmented clinical program.
Name
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Role
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School
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Department
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Sneha S. Jain
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Main PI
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School of Medicine
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Cardiovascular Medicine
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Akshay Chaudhari
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Co-PI
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School of Medicine
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Radiology
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David Maron
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Co-PI
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School of Medicine
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Medicine - Stanford Prevention Research Center
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Fatima Rodriguez
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Co-PI
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School of Medicine
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Cardiovascular Medicine
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