MIPS Researchers Develop Locoregional Delivery of Stem Cell–based Therapies

June 10, 2020

The Interventional Regenerative Medicine and Imaging Lab has published their research utilizing image-guided, minimally invasive procedures for the targeted delivery of stem cell–based therapies to regenerate, replace, or repair damaged organs. Despite many cellular therapies showing promise in the preclinical setting, clinical results have been suboptimal. Most intravenously delivered cells become trapped in the lungs and reticuloendothelial system, resulting in little therapy reaching target tissues. Interventional regenerative medicine aims to increase the efficacy of cell-based therapies by locoregional stem cell delivery via endovascular, endoluminal, or direct injection into tissues. Their review highlights routes of delivery, disease states, and mechanisms of action involved in the targeted delivery of stem cells.

Read the Science Translational Medicine paper
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