Our long-term goal is to identify and characterize the molecular and physiological changes induced by the tumor microenvironment. These changes influence the malignant progression of transformed cells. By understanding the molecular changes important for tumor cells to survive in both nutrient and oxygen depleted conditions, potentially new targets for cancer therapy can be identified.


  • To perform original laboratory and translational research advancing the understanding of the etiology of cancer and enhancing our ability to prevent and treat cancer;
  • To educate students at the graduate and post graduate level and medical residents in the proper conduct of basic research.

Other Research News

Targeting the Phd3/HIF-2 pathway represents a new therapeutic approach for the treatment of diabetes with little toxicity,

News From The Lab

The American Society for Radiation Oncology (ASTRO) has selected Dr. Quynh Le, Katharine Dexter McCormick and Stanley McCormick Memorial professor and chair of the Department of Radiation Oncology, an ASTRO fellow

The American Society for Radiation Oncology (ASTRO) will award Amato J. Giaccia, PhD, with the Society’s highest honor—the ASTRO Gold Medal.