Basic and/or Translational Research
The basic research track will offer formal training in basic and translational science research. The division will assist fellows in the selection of a mentor appropriate to their academic interests. When fellows choose to leave the division for their research, co-mentorship with a divisional faculty member is arranged. For example, a mentor doing genomics research in a field relevant to pulmonary disease outside the division is supported by a divisionally-based mentor to provide greater academic continuity for the trainee.
There will be 14-18 months of protected time during the three-year fellowship in the basic research track, with an optional 4th year of funding for those who continue toward an NIH K award path.
Manoj Maddali, MD
"I chose to come to Stanford due to the rigorous clinical training and ample educational opportunities outside of medicine. For example, the PCCM division has supported me to pursue a fully-funded Masters in Bioinformatics during my 3rd and 4th years of fellowship, offered through the Stanford Department of Biomedical Data Science. Due to the close proximity of the medical and university campus, Stanford is unique in its ability to offer cross-disciplinary mentorship, for example across medicine, bioinformatics, statistics, and computer science. The division has also been supportive of potential diverse career paths ranging from intensive clinical practice to grant-funded research and industry. For these reasons and more, I am thrilled to have joined Stanford for PCCM fellowship!"
|Resource||Significance for Fellows|
|Stanford CTSA||The Stanford CTSA was renewed in July 2019 to enable translational research. This five-year, $53 million grant renewal from the Clinical and Translational Science Award Program enables dozens of pilot grants for senior fellows and junior faculty, a hub of collaboration across disciplines.|
|Wall Center for Pulmonary Vascular Disease||A combined adult-pediatric cardio-pulmonary endowment of $40M dedicated to PAH research and patient care, the center supports internal grants in ILD and PAH, enabling the development of multiple biobanks.|
|Chan Zuckerberg Biohub at Stanford||David Cornfield (PD), co-directs the CZ Biohub at Stanford. The CZ Biohub is a medical research organization that collaborates with Stanford, UC-Berkeley, and UC-San Francisco, and offers two- to three-year research fellowships for medical residents and clinical fellows.|
|Stanford Center for Advanced Lung Disease||Hospital-supported center for the care of patients with ILD, adult CF, and transplants. The center includes one of the most extensive transplant programs in the US, supporting a clinical transplant fellowship and over 50 lung transplants per year, a significant source of tissue for research in lung injury and repair and vascular disease.|
|Pediatric and Adult PH Centers||The adult center is one of the largest PH referral centers in the US, evaluated >2,000 cases of PAH, and gathered clinical data on >800 PH patients since 1997. The pediatric PH center is the third-largest in the US & now consults on or provides care for >125 patients annually|
|Stanford Institutes||Stanford has six long-established interdisciplinary institutes to enhance scientific collaboration between departments and even schools within the University. The Stem Cell Biology, Institute for Immunity, Transplantation, and Infection (ITI), and Cardiovascular Institutes are particularly relevant.|
|Sean N. Parker Center for Allergy & Asthma Research||Donations totaling >$60M were donated to form the center housed in Stanford’s PACCM Division, which focuses on allergies and asthma. Multiple collaborations relevant to pulmonary medicine are enabled through this center, which is directed by Mentor Kari Nadeau.|
|STARR & Quantitative Sciences Unit||Supported in part by the CTSA, Stanford has the well-developed statistical and computing infrastructure to assist with study design, accessing patient populations, and data analysis|
|Biobanks||Biobanking and phenotyping efforts are already established in the fields of PAH, ILD, transplantation and lung injury at Stanford, providing serum and tissue samples for biomarker and translational research|
|Stanford CF Center||Integrated program in CF that follows > 250 patients through adulthood; source of subjects and samples, particularly relevant for CF microbiome work. Combined adult/peds CF program largest in the USA.|
|Translational P01 in Lung Disease||Mentors Roham Zamanian and Marlene Rabinovitch lead a translational P01 grant investigating the role of neutrophil elastase inhibition in PAH. The goal is to explore the efficacy of unique therapies in pre-clinical models and to prepare interventions based on these findings|
|Maternal Child Health Research Institute||The Stanford Maternal and Child Health Research Institute (MCHRI) is dedicated to the health of pregnant women and children. MCHRI fosters transdisciplinary research in the pre-clinical, clinical, and basic sciences. In the past 10 years, the Institute has distributed more than 55 million USD.|
Clinical and/or Health Services Research
The clinical research track enables the trainee obtain a Master’s of Science degree in Clinical Epidemiology, Health Services Research, or another relevant field. This program requires approximately one year of classes and a Master’s thesis, and is funded via competing for a KL2 award through Stanford’s Clinical and Translational Science Award (CTSA). Trainees selecting this track will have 14-18 months of protected time in the first 3 years of fellowship, with funding for a 4th year available for clinical research and completion of the Master’s thesis. As with the basic/translational track, those entering this track will usually apply for a NIH K grant (usually K23) in their 4th year.
For additional information on the wide variety of basic and clinical research opportunities, please see our research section.