Mission
Our center focuses on synergistic development and application of:
- Key proteomic findings will be validated and the underlying mechanisms investigated in human PAH samples and rodent models (Marlene Rabinovitch, Mark Nicolls, Roham Zamanian)
- Phospho-flow cytometry and mass spectrometry for the isotope-based analysis of antibody binding events at the single-cell level (Garry Nolan)
- Mass spectrometry and protein arrays for the characterization of autoantibodies (William Robinson)
- Intel peptide arrays, cytokine/chemokine arrays, and High throughput Immunophenotyping using Transcription (HIT) for profiling secreted proteins (Paul J. Utz)
- Peptoids as antagonists and detector molecules (Thomas Kodadek)
- Novel bioinformatic algorithms for the integration and analysis of related but disparate megasets of proteomic, genomic and clinical data (Robert Tibshirani)
For more information about other NHLBI Proteomic Centers, please click here.