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Basic Life Research Scientist, Biochemistry
Profiles With Related Publications
Euan A. Ashley
Associate Dean, School of Medicine, Roger W. and Joelle G. Burnell Professor of Genomics and Precision Health, Professor of Medicine (Cardiovascular Medicine), of Genetics, of Biomedical Data Science and, by courtesy, of Pathology
Cardiology, Inherited cardiovascular disease, Hypertrophic Cardiomyopathy, Cardiomyopathy, Dilated, Heart Failure, Arrhythmogenic Right Ventricular Dysplasia, Sports Cardiology, Left ventricular non-compaction cardiomyopathy, Genomic medicine, Undiagnosed disease
The Ashley lab is focused on precision medicine. We develop methods for the interpretation of whole genome sequencing data to improve the diagnosis of genetic disease and to personalize the practice of medicine. At the wet bench, we take advantage of cell systems, transgenic models and microsurgical models of disease to prove causality in biological pathways and find targets for therapeutic development.
Alfred Woodley Salter and Mabel G. Salter Endowed Professor of Pediatrics
Pediatric Cardiology, Pediatric Heart Transplantation, Pediatric Heart Failure
1. Using iPSC-derived cardiomyocytes to understand hypertrophic cardiomyopathy and heart failure associated with congenital heart disease.
2. Role of alterations in mitochondrial dycamics and function in normal physiology and disease.
3. Differences between R and L ventricular responses to stress,
4. Immune biomarkers of risk after pediatric VAD implantation.
5. Biomarkers for post-transplant lymphoproliferative disorder.
Rajesh Dash, MD PhD; Director of SSATHI & CardioClick
Associate Professor of Medicine (Cardiovascular Medicine)
South Asian Cardiovascular Risk, Cardiovascular Medicine, Cardiovascular Disease
I have two research areas:
1) Heart disease in South Asians - genetic, metabolic, & behavioral underpinnings of an aggressive phenotype.
2) Imaging cell injury & recovery in the heart. Using Cardiac MRI to visualize signals of early injury and facilitating preventive medical therapy. Optimizing new imaging methods for viable cells to delineate live heart cells or transplanted stem cells.
Associate Professor of Cardiothoracic Surgery (Adult Cardiac Surgery)
Cardiothoracic Surgery, Aortic Diseases, Anomalous Coronary Artery (ACA), Aortic Stenosis, Bicuspid Aortic Valve Disease, Coarctation of the Aorta, Coronary Artery Disease, Rheumatic Heart Disease, Thoracic Aortic Aneurysm (TAA), Valvular Heart Disease, Abdominal Aneurysm Open Repair, Aortic Valve Surgery, Coronary Artery Bypass Graft Surgery, Dissection, Endovascular Aneurysm Repair, Endovascular Stent Graft, Heart Surgery, Heart Valve Replacement/Repair, Marfan Syndrome, Loeys-Dietz Syndrome, Transcatheter Aortic Valve Replacement (TAVR), Thoracic Aortic Aneurysm Open Repair, Trancatheter Aortic Valce Implantation (TAVI), Valvular Surgery, Thoracic Surgery (Cardiothoracic Vascular Surgery)
Molecular and genetic mechanisms of aortic aneurysm/dissection development. Molecular mechanisms of aneurysm formation in Marfan Syndrome. Clinical research interests include thoracic aortic diseases (aneurysms, dissections).
Professor of Neurology and, by courtesy, of Molecular and Cellular Physiology
We are interested in the neuronal mechanisms that underlie synchronous oscillatory activity in the thalamus, cortex and the massively interconnected thalamocortical system. Such oscillations are related to cognitive processes, normal sleep activities and certain forms of epilepsy. Our approach is an analysis of the discrete components (cells, synapses, microcircuits) that make up thalamic and cortical circuits, and reconstitution of components into in silico computational networks.
Basic Life Research Scientist
Clinical Assistant Professor, Medicine
Internal Medicine, Hospitalist medicine
Assistant Professor (Research) of Cardiothoracic Surgery
The Karakikes Lab aims to uncover fundamental new insights into the molecular mechanisms and functional consequences of pathogenic mutations associated with familial cardiovascular diseases.
Instructor, Medicine - Cardiovascular Medicine Instructor, Medicine - Med/Cardiovascular Medicine
Cardiovascular Disease, Heart Failure, Heart Transplantation, Mechanical Circulatory Support, Left Ventricular Assist Device, Inherited Cardiomyopathy, Hypertrophic Cardiomyopathy, Dilated Cardiomyopathy, Nonischemic cardiomyopathy, Cirrhotic Cardiomyopathy, Iron overload cardiomyopathy
Postdoctoral Research Fellow, Molecular and Cellular Physiology
Postdoctoral Research Fellow, Endocrinology, Gerontology, and Metabolism
Sr Res Scientist-Basic Life, Ophthalmology
Publication Topics For This Person
Aortic Valve Stenosis
Brain-Derived Neurotrophic Factor
Calcium Channels, L-Type
Disease Models, Animal
Hypertrophy, Left Ventricular
Mammary Glands, Animal
Mice, Inbred C57BL
Ryanodine Receptor Calcium Release Channel