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Xiaoyu Chen
Life Science Research Professional 3, Psychiatry and Behavioral Sciences - Sleep Medicine
Print Profile
Email Profile
Bio
Bio
Professional
Publications
Honors & Awards
Shoshana Levy Early Career Awards to Support Women in Science, Stanford University (2024)
Autism Speaks Postdoctoral Fellowship, Autism Speaks (2021)
Education & Certifications
Ph.D., Leiden University (2018)
Master of Clinical Medicine, Hebei Medical University, Neurology (2013)
Bachelor of Medicine, Hebei Medical University, Clinical Medicine (2011)
Patents
Sergiu P. Pasca, Xiaoyu Chen & Fikri Birey. "United States Patent US-20240150759-A1 Splicing Modulators for the Treatment of Timothy Syndrome", Leland Stanford Junior University, May 9, 2024
Contact
chenxy@stanford.edu
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Publications (18)
All Publications
(18)
Featured Publications
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Journal Articles
(18)
Profiles With Related Publications
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Helen M. Blau
Donald E. and Delia B. Baxter Foundation Professor, Director, Baxter Laboratory for Stem Cell Biology and Professor, by courtesy, of Psychiatry and Behavioral Sciences
Research Interests
Prof. Helen Blau's research area is regenerative medicine with a focus on stem cells. Her research on nuclear reprogramming and demonstrating the plasticity of cell fate using cell fusion is well known and her laboratory has also pioneered the design of biomaterials to mimic the in vivo microenvironment and direct stem cell fate. Current findings are leading to more efficient iPS generation, cell based therapies by dedifferentiation a la newts, and discovery of novel molecules and therapies.
303
Total Publications
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Michele Calos
Professor of Genetics, Emerita
Research Interests
My lab is developing innovative gene and stem cell therapies for genetic diseases, with a focus on gene therapy and regenerative medicine.
We have created novel methods for inserting therapeutic genes into the chromosomes at specific places by using homologous recombination and recombinase enzymes.
We are working on 3 forms of muscular dystrophy.
We created induced pluripotent stem cells from patient fibroblasts, added therapeutic genes, differentiated, and engrafted the cells.
134
Total Publications
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Sophia Chernikova
Sr Res Scientist-Basic Ls, Neurosurgery
19
Total Publications
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Le Cong
Assistant Professor of Pathology (Pathology Research) and of Genetics
Research Interests
Our lab develops gene-editing technologies like novel CRISPR systems and large gene insertion techniques for gene&cell therapy. We also leverages these gene-editing tools for single-cell functional screening, to probe molecular mechanisms of cancer and immunological diseases. To accelerate our work, we integrate AI and machine learning to design and evolve gene-editing proteins/RNAs in silico, pushing the frontier that bridges computational and experimental biology.
43
Total Publications
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Tina Duong MPT, PhD
Senior Research Scientist, Neurology
106
Total Publications
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Richard Frock
Assistant Professor of Radiation Oncology (Radiation and Cancer Biology)
Research Interests
We are a functional genomics laboratory interested in elucidating mechanisms of DNA repair pathway choice and genome instability. We use genome-wide repair fate maps of targeted DNA double strand breaks (DSBs) to develop pathway-specific models and combinatorial therapies. Our expertise overlaps many different fields including: genome editing, ionizing radiation, cancer therapeutics, V(D)J and IgH class switch recombination, repair during transcription and replication, and meiosis.
33
Total Publications
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Alex Gao
Assistant Professor of Biochemistry
Research Interests
Nature has created many powerful biomolecules that are hidden in organisms across kingdoms of life. Many of these biomolecules originate from microbes, which contain the most diverse gene pool among living organisms. We are integrating high-throughput computational and experimental approaches to harness the vast diversity of genes in microbes to develop new antibiotics and molecular biotechnology, and to investigate the evolution of proteins and molecular mechanisms in innate immunity.
16
Total Publications
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Jin Hao
Postdoctoral Scholar, Psychiatry
6
Total Publications
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Xiaolin Jia
Clinical Assistant Professor, Medicine
Clinical Focus
Internal Medicine, Hospitalist medicine
10
Total Publications
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Konstantin Kaganovsky
Postdoctoral Scholar, Psychiatry
13
Total Publications
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Mark A. Kay, M.D., Ph.D.
Dennis Farrey Family Professor of Pediatrics, and Professor of Genetics
Research Interests
Mark A. Kay, M.D., Ph.D. Director of the Program in Human Gene Therapy and Professor in the Departments of Pediatrics and Genetics. Respected worldwide for his work in gene therapy for hemophilia, Dr. Kay and his laboratory focus on establishing the scientific principles and developing the technologies needed for achieving persistent and therapeutic levels of gene expression in vivo. The major disease models are hemophilia, hepatitis C, and hepatitis B viral infections.
458
Total Publications
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Rebecca Levy
Instructor, Neurology
Clinical Focus
Neurology with Special Qualifications in Child Neurology
23
Total Publications
Publication Topics For This Person
Adenoviridae
Cell Line
DNA End-Joining Repair
Dystrophin
Endonucleases
Epigenesis, Genetic
Exons
Gene Targeting
Genetic Engineering
Genetic Therapy
Genetic Vectors
Genome
Genome, Human
Genotype
HEK293 Cells
HeLa Cells
Long QT Syndrome
Microscopy, Fluorescence
Molecular Conformation
Molecular Sequence Data
Muscular Dystrophy, Duchenne
Mutagenesis
Mutation
Myoblasts
Neurons
Oligonucleotides, Antisense
Organoids
Prosencephalon
RNA, Guide
Viruses