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I am a Physician-Engineer with multidisciplinary training in diverse fields. In my doctoral research, I developed robust technologies of stem cell differentiation and cellular reprogramming for cardiovascular and neural tissue engineering and regenerative medicine applications. My current research combines genome engineering, systems biology, cell biology, molecular biology and engineering principles to investigate organelle (i.e., melanosome and lysosomes) biogenesis in order to understand how organelle level perturbations influence stem cell, tissue and organismal pathophysiology with the aim to engineer novel therapeutics.
Genetic and epigenetic determinants of endolysosomal and related organelles biogenesis<br/><br/>Epigenomic reprogramming in human melanoma initiation<br/><br/>Molecular regulation of stem cell plasticity<br/><br/>Cardiovascular, neural and epidermal tissue engineering and regenerative medicine