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Vali Barsan, MD is an Instructor in the Division of Pediatric Hematology, Oncology, and Stem Cell Transplantation at Stanford University School of Medicine. Dr. Barsan obtained his BS in Bioengineering at UC San Diego Jacobs School of Engineering and then joined Illumina as an engineer to develop and optimize next generation sequencing tools. He earned his MD at Baylor College of Medicine where he studied the biology of cancer metastasis through molecular techniques in the Mani Lab at MD Anderson Cancer Center. Dr. Barsan completed residency in Pediatrics at UC San Diego and fellowship in Pediatric Hematology/Oncology at Stanford University. He is focused on developing and translating genomic technologies in oncology to implement personalized therapy and study mechanisms of effective cancer immunity.
Adoptive T cell immunotherapy entails engineering immune cells to recognize cancer-specific antigens and target them for destruction. Barriers to efficacy can arise from both tumor antigen related as well as T cell related features. I am interested developing noninvasive molecular tools that enable us to understanding these relationships to improve the clinical application and development of cellular immunotherapeutics.