Bio

Bio


My research interest include acute and chronic kidney disease, kidney stones and renal transplantation.

Honors & Awards


  • Science Award, International Pediatric Transplant Association (2019)
  • Clinical Trainee Award, Child Health Research Institute at Stanford (2018)

Boards, Advisory Committees, Professional Organizations


  • Committee member, Fellows Council (2018 - Present)

Publications

All Publications


  • Living or deceased donor kidney transplantation in children. Current opinion in pediatrics Sigurjonsdottir, V. K., Grimm, P. C. 2019

    Abstract

    PURPOSE OF REVIEW: Kidney transplantation is the preferred treatment modality for children with end-stage renal disease. In this review, we discuss the factors affecting the selection of the appropriate donor to ensure the best possible short and long-term outcomes.RECENT FINDINGS: Outcomes of pediatric renal transplantation from living donors are superior to those obtained from deceased donors. Despite this, the rate of living donor kidney transplantation has declined over the last decade. Living donation is considered to be safe but long-term outcomes, especially for parents who are often young donors, are not well understood. Living donation can also cause a financial impact to the donor and family. Barriers to living donation must be sought and defeated. Deceased donor organs are now the primary source of kidneys. How the risk of extended time on dialysis must be weighed against the improved outcomes that may accrue from better matching is controversial. Increasing the donor pool may be accomplished by reassessing sources that are currently avoided, such as donation after cardiac death and infant kidneys transplanted en bloc.SUMMARY: The pediatric nephrologist must balance waiting for the highest quality kidney against the need for the shortest possible waiting time.

    View details for DOI 10.1097/MOP.0000000000000740

    View details for PubMedID 30762703

  • Pediatric acute kidney injury and the subsequent risk for chronic kidney disease: is there cause for alarm? Pediatric nephrology (Berlin, Germany) Sigurjonsdottir, V. K., Chaturvedi, S., Mammen, C., Sutherland, S. M. 2018

    Abstract

    Acute kidney injury (AKI) is characterized clinically as an abrupt decline in renal function marked by reduced excretion of waste products, disordered electrolytes, and disrupted fluid homeostasis. The recent development of a standardized AKI definition has transformed our understanding of AKI epidemiology and outcomes. We now know that in the short term, children with AKI experience greater morbidity and mortality; additionally, observational studies have established that chronic renal sequelae are far more common after AKI events than previously realized. Many of these studies suggest that patients who develop AKI are at greater risk for the subsequent development of chronic kidney disease (CKD). The goal of this review is to critically evaluate the data regarding the association between AKI and CKD in children. Additionally, we describe best practice approaches for future studies, including the use of consensus AKI criteria, the application of rigorous definitions for CKD and renal sequelae, and the inclusion of non-AKI comparator groups. Finally, based upon existing data, we suggest an archetypal approach to follow-up care for the AKI survivors who may be at greater CKD risk, including children with more severe AKI, those who endure repeated AKI episodes, patients who do not experience full recovery, and those with pre-existing CKD.

    View details for DOI 10.1007/s00467-017-3870-6

    View details for PubMedID 29374316

  • Anaplasmosis in pediatric patients: Case report and review. Diagn Microbiol Infect Dis Sigurjonsdottir, V. K. 2017
  • Impact of nephrolithiasis on kidney function. BMC NEPHROLOGY Sigurjonsdottir, V. K. 2015