Ting-Ting Huang

Associate Professor (Research) of Neurology

Academic Appointments

Associate Professor (Research), Neurology
Member, Wu Tsai Neurosciences Institute

Boards, Advisory Committees, Professional Organizations

Committee member, McCormick Fellowship (2012 - Present)
Editorial board, Redox Biology (2013 - Present)
Review Editor, Frontiers in Aging Neuroscience (2015 - Present)
Review Editor, Frontier in Physiology - Redox Biology (2021 - Present)

Professional Education

B.S., Taipei Medical College, Medical Technology (1981)
M.S., University of Oklahoma HSC, Microbiol. and Immunol. (1985)
Ph.D., University of Oklahoma HSC, Microbial Genetics (1988)

2023-24 Courses

Independent Studies
- Directed Reading in Neurology and Neurological Science
  NENS 299 (Aut, Win, Spr, Sum)
- Directed Reading in Neurosciences
  NEPR 299 (Aut, Sum)
- Early Clinical Experience in Neurology and Neurological Sciences
  NENS 280 (Aut, Win, Spr, Sum)
- Graduate Research
  NENS 399 (Aut, Win, Spr, Sum)
- Graduate Research
  NEPR 399 (Aut, Sum)
- Medical Scholars Research
  NENS 370 (Aut, Win, Spr, Sum)
- Undergraduate Research
  NENS 199 (Aut, Win, Spr, Sum)

Graduate and Fellowship Programs

Neurosciences (Phd Program)

All Publications

Profiles With Related Publications

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Anne Brunet

Michele and Timothy Barakett Endowed Professor
Research Interests
Our lab studies the molecular basis of longevity. We are interested in the mechanism of action of known longevity genes, including FOXO and SIRT, in the mammalian nervous system. We are particularly interested in the role of these longevity genes in neural stem cells. We are also discovering novel genes and processes involved in aging using two short-lived model systems, the invertebrate C. elegans and an extremely short-lived vertebrate, the African killifish N. furzeri.

153 Total Publications
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Howard Y. Chang, MD, PhD

Virginia and D. K. Ludwig Professor of Cancer Research and Professor of Genetics
Clinical Focus
Cancer > Cutaneous (Dermatologic) Oncology, Dermatology, General Dermatology
Research Interests
Our research is focused on how the activities of hundreds or even thousands of genes (gene parties) are coordinated to achieve biological meaning. We have pioneered methods to predict, dissect, and control large-scale gene regulatory programs; these methods have provided insights into human development, cancer, and aging.

461 Total Publications
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Gerald Crabtree

David Korn, MD, Professor of Pathology and Professor of Developmental Biology
Research Interests
Chromatin regulation and its roles in human cancer and the development of the nervous system. Engineering new methods for studying and controlling chromatin and epigenetic regulation in living cells.

262 Total Publications
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Dean W. Felsher

Professor of Medicine (Oncology) and of Pathology
Research Interests
My laboratory studies the molecular basis of cancer with a focus on understanding when cancer can be reversed through targeted oncogene inactivation.

217 Total Publications
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Amato J. Giaccia

Jack, Lulu and Sam Willson Professor, Professor of Radiation Oncology, Emeritus
Research Interests
During the last five years, we have identified several small molecules that kill VHL deficient renal cancer cells through a synthetic lethal screening approach. Another major interest of my laboratory is in identifying hypoxia-induced genes involved in invasion and metastases. We are also investigating how hypoxia regulates gene expression epigenetically.

403 Total Publications
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Rona Giffard

Professor of Anesthesiology, Perioperative and Pain Medicine, Emerita
Research Interests
Astrocytes, microglia and neurons interact, and have unique vulnerabilities to injury based on their patterns of gene expression and their functional roles. We focus on the cellular and molecular basis of brain cell injury in stroke. We study the effects of altering miRNA expression, altering levels of heat shock and cell death regulatory proteins. Our goal is to improve outcome by improving mitochondrial function and brain cell survival, and reducing oxidative stress and inflammation.

179 Total Publications
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Livnat Jerby

Assistant Professor of Genetics
Research Interests
Immune responses are highly orchestrated processes that span various interconnected regulatory modalities within and across cells. My lab develops high-throughput, quantitative, engineering-based, approaches to dissect multicellular immune dynamics at unprecedented scale, resolution, and depth, and identify new immunomodulating interventions at an accelerated pace.

25 Total Publications
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Aslam Khan

Clinical Assistant Professor, Pediatrics - Infectious Diseases
Clinical Focus
Pediatric Infectious Diseases

17 Total Publications
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Seung K. Kim M.D., Ph.D.

KM Mulberry Professor, Professor of Developmental Biology, of Medicine (Endocrinology) and, by courtesy, of Pediatrics (Endocrinology)
Research Interests
We study the development of pancreatic islet cells using molecular, embryologic and genetic methods in several model systems, including mice, pigs, human pancreas, embryonic stem cells, and Drosophila. Our work suggests that critical factors required for islet development are also needed to maintain essential functions of the mature islet. These approaches have informed efforts to generate replacement islets from renewable sources for diabetes.

89 Total Publications
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Pei Yi Lin

Postdoctoral Scholar, Molecular and Cellular Physiology

16 Total Publications
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Frank M. Longo, MD, PhD

George E. and Lucy Becker Professor of Medicine and Professor, by courtesy, of Neurosurgery
Clinical Focus
Alzheimer's Disease, Huntington Disease, Neurology
Research Interests
Clinical interests include Alzheimer's disease and Huntington's disease and the development of effective therapeutics for these disorders. Laboratory interests encompass the elucidation of signaling mechanisms relevant to neurodegenerative disorders and the development of novel small molecule approaches for the treatment of neurodegenerative and other neurological disorders.

188 Total Publications
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Susan K. McConnell

Susan B. Ford Professor, Emerita
Research Interests
Susan McConnell has studied the cellular and molecular mechanisms that underlie the development of the mammalian cerebral cortex. Her work focused on the earliest events that pattern the developing forebrain, enable neural progenitors to divide asymmetrically to generate young neurons, propel the migration of postmitotic neurons outward into their final positions, and sculpt the fates and phenotypes of the neurons as they differentiate.

87 Total Publications