Ting-Ting Huang

Associate Professor (Research) of Neurology (Adult Neurology), Emerita

Academic Appointments

Emeritus Faculty, Acad Council, Neurology & Neurological Sciences
Member, Wu Tsai Neurosciences Institute

Boards, Advisory Committees, Professional Organizations

Committee member, McCormick Fellowship (2012 - Present)
Editorial board, Redox Biology (2013 - Present)
Review Editor, Frontiers in Aging Neuroscience (2015 - Present)
Review Editor, Frontier in Physiology - Redox Biology (2021 - Present)

Professional Education

B.S., Taipei Medical College, Medical Technology (1981)
M.S., University of Oklahoma HSC, Microbiol. and Immunol. (1985)
Ph.D., University of Oklahoma HSC, Microbial Genetics (1988)

Current Research and Scholarly Interests

We study the role of oxygen free radicals in oxidative tissue damage and degeneration. Our research tools include transgenic and knockout mice and tissue culture cells for in vitro gene expression.

2024-25 Courses

Independent Studies
- Directed Reading in Neurology and Neurological Science
  NENS 299 (Aut, Win, Spr, Sum)
- Directed Reading in Neurosciences
  NEPR 299 (Aut, Win, Spr, Sum)
- Early Clinical Experience in Neurology and Neurological Sciences
  NENS 280 (Aut, Win, Spr, Sum)
- Graduate Research
  NENS 399 (Aut, Win, Spr, Sum)
- Graduate Research
  NEPR 399 (Aut, Win, Spr, Sum)
- Medical Scholars Research
  NENS 370 (Aut, Win, Spr, Sum)
- Undergraduate Research
  NENS 199 (Aut, Win, Spr, Sum)

Graduate and Fellowship Programs

Neurosciences (Phd Program)

All Publications

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Our lab studies the molecular basis of longevity. We are interested in the mechanism of action of known longevity genes, including FOXO and SIRT, in the mammalian nervous system. We are particularly interested in the role of these longevity genes in neural stem cells. We are also discovering novel genes and processes involved in aging using two short-lived model systems, the invertebrate C. elegans and an extremely short-lived vertebrate, the African killifish N. furzeri.

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Howard Y. Chang, MD, PhD

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Mei-Sze Chua

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Gerald Crabtree

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Aly Elezaby, MD PhD

Instructor, Medicine - Cardiovascular Medicine
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Dean W. Felsher

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My laboratory studies the molecular basis of cancer with a focus on understanding when cancer can be reversed through targeted oncogene inactivation.

221 Total Publications
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Rona Giffard

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Astrocytes, microglia and neurons interact, and have unique vulnerabilities to injury based on their patterns of gene expression and their functional roles. We focus on the cellular and molecular basis of brain cell injury in stroke. We study the effects of altering miRNA expression, altering levels of heat shock and cell death regulatory proteins. Our goal is to improve outcome by improving mitochondrial function and brain cell survival, and reducing oxidative stress and inflammation.

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Kevin Kelley

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Aslam Khan

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Seung K. Kim M.D., Ph.D.

KM Mulberry Professor, Professor of Developmental Biology, of Medicine (Endocrinology) and, by courtesy, of Pediatrics (Endocrinology)
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We study the development of pancreatic islet cells using molecular, embryologic and genetic methods in several model systems, including mice, pigs, human pancreas, embryonic stem cells, and Drosophila. Our work suggests that critical factors required for islet development are also needed to maintain essential functions of the mature islet. These approaches have informed efforts to generate replacement islets from renewable sources for diabetes.

89 Total Publications
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Frank M. Longo, MD, PhD

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Alzheimer's Disease, Huntington Disease, Neurology
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195 Total Publications
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Susan K. McConnell

Susan B. Ford Professor, Emerita
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Susan McConnell has studied the cellular and molecular mechanisms that underlie the development of the mammalian cerebral cortex. Her work focused on the earliest events that pattern the developing forebrain, enable neural progenitors to divide asymmetrically to generate young neurons, propel the migration of postmitotic neurons outward into their final positions, and sculpt the fates and phenotypes of the neurons as they differentiate.

87 Total Publications