Current Research and Scholarly Interests
My research interests extend over the broad spectrum of pharmacogenetics, computational biology and bioinformatics. Applications include the development of a pharmcogenetics knowledge base, structure-function relationships, de novo modeling and the structural basis of disease. .
My current research areas involve the studies of the following:
* development of an integrated knowledge base about how variation in human genetics leads to variation in our response to drugs
* the stability of the collagen triple helix
* the relationship and prediction of lethal mutations for the genetic collagenous disease Osteogenesis imperfecta