Current Research and Scholarly Interests
My research interests extend over the broad spectrum of pharmacogenomics, personalized medicine, computational biology and bioinformatics. Applications include the development of a pharmcogenomics knowledge base, clinical dosing guidelines for pharmacogenomics, annotation of human genome, de novo modeling and the structural basis of disease.
My current research areas involve the studies of the following:
* development of an integrated knowledge base about how variation in human genetics leads to variation in our response to drugs
* the stability of the collagen triple helix
* the relationship and prediction of lethal mutations for the genetic collagenous disease Osteogenesis imperfecta
